Impulsive Reaction-Diffusion Delayed Models in Biology: Integral Manifolds Approach

In this paper we study an impulsive delayed reaction-diffusion model applied in biology. The introduced model generalizes existing reaction-diffusion delayed epidemic models to the impulsive case. The integral manifolds notion has been introduced to the model under consideration. This notion extends the single state notion and has important applications in the study of multi-stable systems. By means of an extension of the Lyapunov method integral manifolds’ existence, results are established. Based on the Lyapunov functions technique combined with a Poincarè-type inequality qualitative criteria related to boundedness, permanence, and stability of the integral manifolds are also presented. The application of the proposed impulsive control model is closely related to a most important problems in the mathematical biology—the problem of optimal control of epidemic models. The considered impulsive effects can be used by epidemiologists as a very effective therapy control strategy. In addition, since the integral manifolds approach is relevant in various contexts, our results can be applied in the qualitative investigations of many problems in the epidemiology of diverse interest.

Tracking and vibration control of a free-floating space manipulator system with flexible links and joints

The problem of modeling and controlling of a free-floating space manipulator with flexures in both links and joints is addressed in this study. A mathematical model of the system is developed by combining Lagrange’s equations and momentum conservation. The finite element method is introduced to discretize multi-links with complex cross-sections. In order to reduce the dimensions and maintain the precision of a rigid-flexible coupled system, an iterated improved reduction system method is adopted. Then, a novel composite control scheme for the reduced system is presented that uses the concept of integral manifolds and singular perturbation theory. Finally, an augmented computed torque controller is applied to the under-actuated slow subsystem to realize trajectory tracking in joint space, while a linear-quadratic controller is designed to damp out the vibration of joints and links. Numerical simulation results verified that the proposed hybrid controller can successfully suppress vibration and track trajectory at the same time.

On construction of a field of forces along given trajectories in the presence of random perturbations

In this paper, a force field is constructed along a given integral manifold in the presence of random perturbing forces. In this case, two types of integral manifolds are considered separately: 1) trajectories that depend on generalized coordinates and do not depend on generalized velocities, and 2) trajectories that depend on both generalized coordinates and generalized velocities. The construction of the force field is carried out in the class of second-order stochastic Ito differential equations. It is assumed that the functions in the right-hand sides of the equation must be continuous in time and satisfy the Lipschitz condition in generalized coordinates and generalized velocities. Also this functions satisfy the condition for linear growth in generalized coordinates and generalized velocities.These assumptions ensure the existence and uniqueness up to stochastic equivalence of the solution to the Cauchy problem of the constructed equations in the phase space, which is a strictly Markov process continuous with probability 1. To solve the two posed problems, stochastic differential equations of perturbed motion with respect to the integral manifold are constructed. Moreover, in the case when the trajectories depend on generalized coordinates and do not depend on generalized velocities, the second order equations of perturbed motion are constructed, and in the case when the trajectories depend on both generalized coordinates and generalized velocities, the first order equations of perturbed motion are constructed. And further, in both cases by Erugin’s method necessary and sufficient conditions for solving the posed problems are derived.

Decomposition and stability of linear singularly perturbed systems with two small parameters

In the domain $\Omega =\left\{\left(t,\varepsilon _{1}, \varepsilon _{2} \right): t\in {\mathbb R},\varepsilon _{1}>0, \varepsilon _{2} >0\right\}$, we consider a linear singularly perturbed system with two small parameters \[ \left\{ \begin{array}{l} {\dot{x}_{0} =A_{00} x_{0} +A_{01} x_{1} +A_{02} x_{2},} \\ {\varepsilon _{1} \dot{x}_{1} =A_{10} x_{0} +A_{11} x_{1} +A_{12} x_{2},} \\ {\varepsilon _{1} \varepsilon _{2} \dot{x}_{2} =A_{20} x_{0} +A_{21} x_{1} +A_{22} x_{2},} \end{array}\right. \] where $x_{0} \in {\mathbb R}^{n_{0}}$, $x_{1} \in {\mathbb R}^{n_{1}}$, $x_{2} \in {\mathbb R}^{n_{2}}$. In this paper, schemes of decomposition and splitting of the system into independent subsystems by using the integral manifolds method of fast and slow variables are investigated. We give the conditions under which the reduction principle is truthful to study the stability of zero solution of the original system.

Global Stability of Integral Manifolds for Reaction–Diffusion Delayed Neural Networks of Cohen–Grossberg-Type under Variable Impulsive Perturbations

The present paper introduces the concept of integral manifolds for a class of delayed impulsive neural networks of Cohen–Grossberg-type with reaction–diffusion terms. We establish new existence and boundedness results for general types of integral manifolds with respect to the system under consideration. Based on the Lyapunov functions technique and Poincarѐ-type inequality some new global stability criteria are also proposed in our research. In addition, we consider the case when the impulsive jumps are not realized at fixed instants. Instead, we investigate a system under variable impulsive perturbations. Finally, examples are given to demonstrate the efficiency and applicability of the obtained results.

On the theory of integral manifolds for some delayed partial differential equations with nondense domain}

UDC 517.9 Integral manifolds are very useful in studying dynamics of nonlinear evolution equations. In this paper, we consider the nondensely-defined partial differential equation ⅆ u ⅆ t = ( A + B ( t ) ) u ( t ) + f ( t , u t ) , t ∈ R , ( 1 ) where ( A , D ( A ) ) satisfies the Hille – Yosida condition, ( B ( t ) ) t ∈ R is a family of operators in ℒ ( D ( A ) ¯ , X ) satisfying some measurability and boundedness conditions, and the nonlinear forcing term f satisfies ‖ f ( t , ϕ ) - f ( t , ψ ) ‖ ≤ φ ( t ) ‖ ϕ - ψ ‖ 𝒞 , here, φ belongs to some admissible spaces and ϕ , ψ ∈ 𝒞 : = C ( [ - r ,0 ] , X ) . We first present an exponential convergence result between the stable manifold and every mild solution of (1). Then we prove the existence of center-unstable manifolds for such solutions.Our main methods are invoked by the extrapolation theory and the Lyapunov – Perron method based on the admissible functions properties.