Fostering an entrepreneurial mindset: A typology for aligning instructional strategies with three dominant entrepreneurial mindset conceptualizations

Entrepreneurship education in higher education institutions (HEIs) increasingly aims at fostering an entrepreneurial mindset (EM) in students. However, large heterogeneity exists in conceptualizations of EM. This is a challenge for educators as it is difficult to develop instructional strategies to foster students’ EM when there is no clarity about what this mindset is. The purpose of the article is to address this challenge. It does so by analysing and synthesizing current literature in the field of entrepreneurship education in HEIs and develops a taxonomy that depicts three dominant conceptualizations of EM, their theoretical origins and the type of attributes typically associated with each conceptualization. The article goes beyond the integrative literature review by reflecting on the consequences for the design of entrepreneurship education of the simultaneous existence of these three dominant conceptualizations. The author develops a typology for aligning instructional strategies with the EM conceptualizations and thus contributes to practice by providing a better understanding of how to achieve coherence between learning outcomes and instructional choices. The article advances the field’s conceptual knowledge about EM and thereby facilitates future theory generation.

Drawing as a method of researching social representations

This paper explores the possibilities of drawing as a method of researching social representations. The theory of social representations focuses on studying the forms, contents, and functions of socially shared common knowledge. In this paper, we (1) present the central premises of social representations theory, (2) elaborate drawing as a visual research method, and (3) synthesize how the drawing method may promote and diversify our understanding of social representations. We suggest that the drawing method is especially fruitful in the analysis of objectification process (how something abstract is made tangible); cognitive polyphasia (the idea of the simultaneous existence of diverse and contradicting social representations); and the different levels of analysis in which social representations become observable: ontogenesis (individual level), microgenesis (social interaction level), and sociogenesis (societal level). Through these insights, this paper advances the current understanding of the drawing method in qualitative social representations research.

Hamiltonian energy computation and complex behavior of a small heterogeneous network of three neurons: circuit implementation

Brain functions are sometimes emulated using some analog integrated circuits based on the organizational principle of natural neural networks. Neuromorphic engineering is the research branch devoted to the study and realization of such circuits with striking features. In this contribution, a novel small network of three neurons is introduced and investigated. The model is built from the coupling between two 2D Hindmarsh–Rose neurons through a 2D FitzHugh–Nagumo neuron. Thus, a heterogeneous coupled network is obtained. The biophysical energy released by the network during each electrical activity is evaluated. In addition, nonlinear analysis tools such as two-parameter Lyapunov exponent, bifurcation diagrams, the graph of the largest Lyapunov exponent, phase portraits, time series, as well as the basin of attractions are used to numerically investigate the network. It is found that the model can experience hysteresis justified by the simultaneous existence of three distinct electrical activities using the same set of parameters. Finally, the circuit implementation of the network is addressed in PSPICE to further support the obtained results.

Evolutionary adaptation of DHFR via expression of enzyme isoforms with various binding properties and dynamics behavior: a bioinformatics and computational study

We compared the binding properties and dynamics of three experimentally reviewed isoforms of human dihydrofolate reductase (DHFR). The cytoplasmic variants including isoforms1 and 2 (iso1 and iso2) are produced by alternative splicing; while the mitochondrial form is located in the mitochondria. The iso1 as the canonical sequence contains 187 residues, and iso2 differs from the iso1, where it has 1–52 residues missing at the N-terminus of canonical sequence. Here, the structural models of the iso2 and mitochondrial forms were constructed by the MODELLER program using the crystal structure of the iso1 as the template. Bioinformatics analysis on ligand-bearing structures demonstrates that mitochondrial variant forms more stable complex with ligands compared with iso1 and 2, indicating their different binding properties. The root mean square fluctuation (RMSF) data suggest that C-terminus of iso1 contains two representative highly flexible fragments, while iso2 contains a highly flexible fragment at N-terminus end. Interestingly, both ends of mitochondrial variant have a degree of rigidity. Finally, the observation of differences in structural dynamics and binding properties predicts that the simultaneous existence of enzyme isoforms is a way to increase the speed of the enzyme maneuver in response to various environmental conditions. This prediction needs to be tested experimentally.

The State, Crisis, and Working-Class Strategy in Antonio Gramsci’s Prison Notebooks

This article conducts a philological and diachronic reconstruction of the emergence and progressive formation of Gramsci’s theory of the state in the Prison Notebooks, in the process demonstrating its organic nexus with a specific conception of the nature and dynamics of crises, and its implications for working-class strategy in the struggle to construct a hegemonic alternative to the capitalist state. On the basis of this analysis, it seeks to extract the contemporary relevance of Gramsci’s theory of the integral state, political crises and his strategic proposal of the war of position for our contemporary global conjuncture, defined by the simultaneous existence of multiple interlocking crises – economic, public health, ecological and social.

The simultaneous existence of modernist and neo-avant-garde tendencies in nonconformist art of Ukraine in the 1980s

In the early 1980s, the nonconformist art movement in Odesa, which had been developing since the mid-1950s, was widened by a new generation of artists. Their art searches differed significantly from their senior colleagues, which led to the formation of a separate movement within nonconformism, which later became known as APTART. The differences were mainly in the worldview of artists, aesthetics, themes, artistic techniques. The art of the new generation was closer to the Western neo-avant-garde, while their older colleagues tended toward modernism. The presence of two different well-defined movements within the nonconformism, a phenomenon in itself countercultural to official culture, distinguished the artistic process in Odesa in the 1980s from other cities in Ukraine. It is these features of the artistic life of that time, still insufficiently covered and analysed. The text considers the part of the work of the Odesa APTART artists, which the most clearly displays the elements of neo-avant-garde aesthetics, that, accordingly, affected the artistic means: acts, performances happenings; the differences between the two groups of artists belonging to the nonconformist subculture were analysed. Specific acts, works of the APTART artists opposed to the background of creative activity of their colleagues are considered. The stages of the APTART artists’ creativity development are traced. Within the disclosure of the research theme, the text highlights the processes of nonconformist artistic life in the main cities of Ukraine, traces parallels to similar phenomena in world art. Due to the experience of recent researches, the terms that directly affect the subject of the paper are specified: nonconformism, informal art, avant-garde, modernism, neo-avant-garde.

Direct, inverse and mirror wave modes of coupled displacements and microrotations monochromatic plane waves in hemitropic micropolar media

В статье обсуждаются вопросы распространения монохроматических волн в гемитропном микрополярном континууме. Сформулированы уравнения динамики гемитропного микрополярного упругого тела в терминах псевдотензоров с 9-ю определяющими псевдоскалярами. Рассмотрены преобразования указанных уравнений в случаях инверсии пространства и зеркального отражения относительно заданной плоскости. Показано наличие инверсных волновых мод (наряду с прямыми) в распространяющейся плоской волне. Получены формулы преобразования прямых волновых мод перемещений и микровращений в инверсные и зеркально отраженные моды. Приводятся соответствующие формулы. The paper deals with the propagation of monochromatic plane waves in a hemitropic micropolar continuum. The dynamics equations of a hemitropic micropolar elastic solid in terms of pseudotensors with 9 constitutive pseudoscalars are derived and discussed. Formulae for the cases of space inversion and mirror reflection relative to a given plane are obtained and considered. The simultaneous existence of the direct, inverse and mirror reflected wave modes in propagating plane waves is established. Formulae for direct wave modes of displacements and microrotations in inverse and mirror modes are given.

Coexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report

The coexistence of dual hematological neoplasms is an unusual and challenging presentation due to the different combination of etiopathology. The presentation of synchronous dual hematological malignancies can be one of the 3 types: myeloid + lymphoid or dual lymphoid or dual myeloid. Here, we are reporting a case of a 53-year-old male with simultaneous presence of JAK<i>2 V617F</i>-positive myeloproliferative neoplasm with features favoring prefibrotic phase of primary myelofibrosis (pre-PMF) in combination with monoclonal gammopathy of undetermined significance (MGUS). In such cases of simultaneous existence of dual hematological neoplasm management, it is recommended to treat the more aggressive one. Currently, our management plan is focusing on treating the pre-PMF and observation of MGUS with regular monitoring for transformation to MM.

Unique Peptide Signatures Of SARS-CoV-2 Against Human Proteome Reveal Variants’ Immune Escape And Infectiveness

SummarySARS-CoV-2 pandemic has emerged the necessity of the identification of sequences sites in viral proteome appropriate as antigenic sites and treatment targets. In the present study, we apply a novel approach for deciphering the virus-host organism interaction, by analyzing the Unique Peptides of the virus with a minimum amino acid sequence length defined as Core Unique Peptides (CrUPs) not of the virus per se, but against the entire proteome of the host organism. The result of this approach is the identification of the CrUPs of the virus itself, which do not appear in the host organism proteome. Thereby, we analyzed the SARS-CoV-2 proteome for identification of CrUPs against the Human Proteome and they are defined as C/H-CrUPs. We found that SARS-CoV-2 include 7.503 C/H-CrUPs, with the SPIKE_SARS2 being the protein with the highest density of C/H-CrUPs. Extensive analysis indicated that the P681R mutation produces new C/H-CrUPs around the R685 cleavage site, while the L452R mutation induces the loss of antigenicity of the NF9 peptide and the strong(er) binding of the virus to ACE2 receptor protein. The simultaneous existence of these mutations in variants like Delta results in the immune escape of the virus, its massive entrance into the host cell, a notable increase in virus formation, and its massive release and thus elevated infectivity.

“Consent Is F#@king Required”: Hashtag Feminism Surrounding Sexual Consent in a Culture of Postfeminist Contradictions

Hashtag feminism exists in a time of postfeminist contradictions marked by the simultaneous existence of popular feminism and popular misogyny. In one such contradiction, popular feminism has led women to expect the successful negotiation of sexual consent, while popular misogyny permits the circulation of traditional sexual scripts that disregard the necessity of consent. In this study, we analyze messages conveyed through digitized narratives of sexual consent posted on Tumblr, a social media site that is popular among feminist activists, to identify the ways that users construct meaning around the dissonance between expectations for consent and the inequalities that inhibit its negotiation. We specifically explore whether hashtag feminism navigates postfeminist contradictions in a way that simultaneously calls out misogyny and calls on feminism. We find that the Tumblr posts in our sample did both, albeit in a manner that failed to offer tangible solutions to the problem at hand. Calls on feminism were largely limited to tagging feminist allies and recirculating existing feminist campaigns. Thus, we argue that the hashtag ultimately became a handoff to a larger feminist abstraction. Future research should explore conditions under which activists link tangible issues, actors, and agendas to an otherwise abstract popular feminism.