Albuminuria intensifies the link between urinary sodium excretion and central pulse pressure in the general population: the Wakuya study

Background Central pulse pressure is responsible for the hemodynamics of vital organs, and monitoring this parameter is important for cardiovascular disease prevention. Excess sodium intake and (micro)albuminuria (a manifestation of renal microvascular damage) are known to be strong predictors of cardiovascular disease. We sought to investigate the cross-sectional relationships among dietary sodium intake, albuminuria, and central pulse pressure in a general population cohort. Methods The subjects were 933 apparently healthy adults (mean age, 56 ± 10 years). Radial pressure waveforms were recorded with applanation tonometry to estimate mean arterial pressure, central pulse pressure, forward and backward pressure amplitudes, and augmentation index. The urinary sodium/creatinine and albumin/creatinine ratios were measured in spot urine samples. Results Both the urinary sodium/creatinine and albumin/creatinine ratios were positively correlated with central pulse pressure, even after adjusting for mean arterial pressure (P < 0.001). Moreover, both ratios had a synergistic influence on increasing the central pulse pressure independent of age, sex, estimated glomerular filtration rate, hyperlipidemia, and diabetes (interaction P = 0.04). A similar synergistic influence was found on the forward pressure amplitude, but not on the backward pressure amplitude or augmentation index. The overall results were not altered when the urinary albumin/creatinine ratio was replaced with the existence of chronic kidney disease. Conclusion (Micro)albuminuria strengthens the positive association between urinary sodium excretion and central pulse pressure and systolic forward pressure. Excess sodium intake may magnify the cardiovascular risk by widening the aortic pulsatile pressure, particularly in the presence of concomitant chronic kidney disease.

Estimation of sodium and potassium intakes assessed by two 24-hour urine collections in a city of Indonesia

Intakes of excess sodium [Na] and insufficient potassium [K] are two major contributors of heart diseases and stroke development. However, no precise study has existed on Na and K intakes among Indonesian adults. This study aimed to estimate the Na and K intakes using two consecutive 24-h urine collections. Participants were community-dwelling adults aged between 20 and 96 years, randomly selected from a pool of resident registration numbers. Of the 506 participants, 479 (240 men and 239 women) completed urine collections. The mean Na excretion was 102.8 and 100.6 mmol/d, while the mean K excretion was 25.0 and 23.4 mmol/d for men and women, respectively. Na and K excretions were higher in participants with a higher body mass index (BMI). A higher K excretion was associated only with younger age. More than 80% of the participants consumed more than 5 g/d of salt (the upper limit recommended by the Indonesian government). Whereas none of them consumed more than 3,510 mg/d of K (the lower limit). The high Na and low K intakes, especially high Na among participants with high BMI, should be considered when the intervention programs are future planned in this country.

Policy Progress in Reducing Sodium in the American Diet, 2010–2019

Most Americans consume dietary sodium exceeding age-specific government-recommended targets of 1,500–2,300 mg/day per person. The majority (71%) of US dietary sodium comes from restaurant and packaged foods. Excess sodium intake contributes to hypertension and cardiovascular disease, which is the leading cause of death in the United States. This review summarizes evidence for policy progress to reduce sodium in the US food supply and the American diet. We provide a historical overview of US sodium-reduction policy (1969–2010), then examine progress toward implementing the 2010 National Academy of Medicine (NAM) sodium report's recommendations (2010–2019). Results suggest that the US Food and Drug Administration made no progress in setting mandatory sodium-reduction standards, industry made some progress in meeting voluntary targets, and other stakeholders made some progress on sodium-reduction actions. Insights from countries that have significantly reduced population sodium intake offer strategies to accelerate US progress toward implementing the NAM sodium-reduction recommendations in the future.

Leaves contents of nutrients in Cryptostegia madagascariensis in different salinized soils

The species C. madagascariensis occurs in humid and arid areas, thus, the species has been standing out as an invasive plant. An experiment was developed in greenhouse with the objective of evaluating the leaf contents (nutritional status) of plants of these invasive plants subjected to different levels of salinity and humidity. The treatments were arranged in randomized blocks, with four repetitions, following the factorial arrangement of 4x4x2, corresponding to the five levels of salinity or incubations (0.3; 1.0; 2.0 and 4.0 dS m-1), four moisture contents (20% of CC; 40% of CC; 70% of CC and 110% of CC) maintained until the end of the test and with two types of soils (Floss Neossol and Vertisolo). Initially, two soils were used, a Floss Neossol and a Vertisol. Leaf samples were analyzed to determine the levels of N, P, K and Na. The soils were placed in pots with a capacity of 21 liters, where each pot contained 19 kg of soil and 4 plants per plot in randomized blocks with 4 repetitions. After elapsed 152 days after sowing, samples of plant tissue (leaves) were taken for chemical analysis. At the end of the experiment, the following leaf variables were carefully evaluated: Nitrogen (N); Phosphorus (P), Potassium (K+) and Sodium (Na+). The increase in humidity in both soils under growth of young plants increased sodium levels and reduced potassium levels in plant tissue resulting from excess sodium in the two soils as a function of salinity and humidity.

From insulator to oxide-ion conductor by a synergistic effect from defect chemistry and microstructure: acceptor-doped Bi-excess sodium bismuth titanate Na0.5Bi0.51TiO3.015

Low levels of acceptor-type dopants can introduce appreciable levels of oxide-ion conductivity into NB0.51T due to a synergistic effect from defect chemistry and ceramic microstructure.

Facile simultaneous synthesis of tetraaniline nanostructures/silver nanoparticles as heterogeneous catalyst for the efficient catalytic reduction of 4-nitrophenol to 4-aminophenol

Nanocomposites of tetraaniline/silver nanoparticles were synthesised using an interfacial polymerisation method. The catalytic activity was investigated for the model reduction of 4-nitrophenol to 4-aminophenol in the presence of excess sodium borohydride.

Nutritional profile of sugar-sweetened beverages destined to the youngsters marketed in Brazil and Portugal

ABSTRACT Objective To analyze and compare the sugar content in sugar sweetened beverages in Brazil and Portugal, according to the Pan American Health Organization nutritional profile model. Methods One hundred six equivalent sugary beverages were selected in the markets of São Paulo, Brazil and Porto, Portugal. Nutritional information reported on the labels was reviewed, according to the Pan American Health Organization nutritional profile model, regarding the critical content of free sugars, salt, total saturated fats and trans fatty acids. Results The Brazilian nectars presented higher amounts of sugar and vitamin C compared to Portuguese nectars that contained more protein. The juices in Portugal contained a higher content of vitamin C and Portuguese dairy beverages had higher levels of protein and sodium, while the Brazilian ones had more total fats. According to the critical nutrients proposed by the Pan American Health Organization, Brazil had excess sodium in dairy beverages and soft drinks, while in Portugal excess sodium was found in nectars and dairy beverages. In both countries, excess free sugars were present in all beverages. Conclusion The amount of sugar in the beverages represents an important contribution of added sugar, especially in the Brazilian nectars. The identification of this component in sugary beverages is fundamental for the adoption of strategies of food education to control obesity.