Potential Health Benefits of Fenugreek With Multiple Pharmacological Properties

Fenugreek is one of the familiar spices found in human food and has been used extensively for curing numerous disorders. It provides natural food fibers and other nutrients required in the human body. It is used in functional foods, traditional foods, and nutraceuticals as well as in physiological uses such as antidiabetic agent, antibacterial, hypocholesterolemic, hypoglycemic, antioxidant, enzymatic pathway, and modifier gastric stimulant. It has a valuable influence on digestion and also has the capability to modify food texture. In modern food technology, it is used as a food stabilizer, adhesive, and emulsifying agent due its fiber, protein, and gum content. Recent pharmocological exploration of the seed extract of this plant discovered anticancer properties. Although it has many potential effects, there are some side effects as well; therefore, there is a greater need to study the pharmacological and toxicological effects of fenugreek to examine its clinical efficacy and safety.

Fenugreek Seed

Fenugreek (Trigonella foenum graecum), native to southern Europe and Asia, is anannual herb with white flowers and hard, yellowish brown and angular seeds,known from ancient times, for nutritional value beside of it medicinal effects. Fenugreek seeds are rich source of gum, fiber, alkaloid, flavonoids, saponin and volatile content. Due to it's high content of fiber, fenugreek could be used as food stabilizer, adhesive and emulsifying agent to change food texture for some special purposes. Some evidences suggest that fenugreek may also be regarded as antidiabetic, anticarcinogenic, remedy for hypocholesterolemia and hypoglycemia, antioxidant, antibacterial agent, gastric stimulant, and anti-anorexia agent. The present article is aimed to review the potential applications of fenugreek as a functional food and nutraceutical. Keywords: Chemical composition, Fenugreek gum, Fenugreek, Health benefits

Global Status and Novel Applications of Natural Gums: An Overview

Natural gums are extracted from different types of natural origins. It is found in the woody elements of plants or seed coatings in the terrestrial environment and also found in seaweeds in the marine environment. Natural gums are otherwise called polysaccharides. Nowadays, there has been a remarkable development in natural products, especially in natural gums that have been used for a variety of purposes such as binders, emulsifying agent suspending agents, etc. In recent years, researchers are focused to produce biodegradable, non-toxic, and low-cost natural materials as these products help in the improvement of human health and provide novel beneficial manner. Moreover, natural polymers were used as a functional food in ancient peoples. In this review, the recent investigations and developments of natural gums have been discussed.

Formulasi Spray Gel Minyak Atsiri Kayu Cendana (Santalum album L.)

Secara empiris Cendana (Santalum album L.) digunakan sebagai antidepresan, antiinflamasi, antijamur, astringent, obat penenang, insektisida, dan antiseptik. Penggunaan tanaman obat dapat ditingkatkan kenyamanannya dengan memformulasikan dalam bentuk sediaan obat. Salah satu sediaan topikal yang cocok untuk inflamasi adalah spray gel. Sediaan spray ini lebih praktis dalam penggunaannya dan juga lebih aman sebab tingkat kontaminasi mikroorganisme lebih rendah karena penggunaannya yang disemprotkan tanpa kontak langsung dengan tangan seperti halnya sediaan topikal lainnya. Konsistensi gel yang memiliki daya lekat cukup tinggi membuat waktu kontak obat yang relatif lebih lama dibanding sediaan lainnya. Pada pembuatan spray gel dengan kandungan minyak atsiri diperlukan adanya emulsifying agent. Carbopol sebagai emulsifying agent yang dipilih dalam formulasi spray gel minyak atsiri cendana, akan dapat menstabilkan zat aktif berbentuk minyak dalam basis berair dengan cara menurunkan tegangan permukaan fase air dan fase minyak. Penelitian ini merupakan penelitian laboratorium murni dengan observasional eksperimental. Teknik pengumpulan data dilakukan dengan skala pengamatan dan pengukuran. Pengamatan diakukan terhadap organoleptik dan homogenitas sediaan, serta pengukuran dilakukan terhadap pH, pola penyemprotan, daya sebar lekat dan stabilitas mekanik. Dilakukan analisis statistik terhadap data hasil uji bobot pola penyemprotan dan dilanjutkan dengan uji independent t-test. Berdasarkan hasil penelitian dapat disimpulkan bahwa formulasi spray gel minyak atsiri kayu cendana (Santalum album L.) dengan variasi carbopol 0,1% (F1) memiliki pola penyemprotan yang baik, dan dengan carbopol 0,3% (F2) memiliki daya lekat yang baik.

Basic Concepts of Nanoemulsion and its Potential application in Pharmaceutical, Cosmeceutical and Nutraceutical fields

One of the widely efficient and noteworthy nanocarriers that could draw a great attention toward pharmaceutical fields is nanoemulsions (NEs). NEs are thermodynamically stable colloidal dispersions composed of two immiscible liquids, oil and water that mixed together using emulsifying agent (surfactant and co-surfactant). It regarded as pharmaceutical dosage form having droplet size within a nanometer range, hence it has extensively considered as carrier for delivering active agents. Such carrier is fabricated in order to overcome some obstacles associated with conventional drug delivery systems especially low bioavailability. The objective of this review is to present an overview about NE and its latest applications in diverse areas such as drug delivery, cosmeceutical and nutraceutical. Clarifications about different mechanisms of NEs development that are frequently used were provided. Correspondingly, popular characterization techniques for NEs such as determination of particle size, polydispersity index (PDI), zeta potential and viscosity were reviewed. Eventually, summary of physical and chemical instability in addition to the regulatory aspects of NE were provided.

The Effect of Weighting Materials on the Rheological Properties of Iraqi and Commercial Bentonite in Direct Emulsion

Numerous drilling additives and materials are used continuously because they are necessary to support and give the required properties of the drilling fluid so that to ensure the stability of the borehole. This paper aspires to evaluate the rheological properties of bentonite (montmorillonite) Trefawey as an alternative to using commercial bentonite. Monitoring and evaluating of the rheological and filtration properties were prepared. This exertion aims to focus on the effect of hematite, and barite on the rheological properties of the three aforementioned bentonite types. An improvement in the rheological properties of bentonite (montmorillonite). Trefawey was observed after adding the previous heavy materials. Hematite has by some means better ability to improve rheological properties compared to other heavy materials. The emulsifying agent used was Carboxyl Methyl Cellulose (HOCH2COONA), as it has provided excellent results parallel to the lignite. The rheological properties of bentonite (montmorillonite) Trefawey are enhanced by doubling the amount of carboxyl methyl cellulose (HOCH2COONA). The results have proved that the use of weighting materials and emulsifying agent affected the rheological properties of bentonite (montmorillonite) Trefawey in a direct emulsion. The results have shown that it is more appropriate to use carboxyl methyl cellulose as an emulsifying agent to prepare a direct emulsion than bentonite (montmorillonite) Trefawey due to its excellent effect in improving the rheological properties of bentonite (montmorillonite) Trefawey. And it can be said that this effort has succeeded in studying two effects simultaneously. In other words, both heavy substances and emulsifying agent have effects on bentonite (montmorillonite) Trefawey, in order to obtain a stable emulsion and a clearer view of the behavior of Iraqi bentonite. The above effort has focused on making bentonite (montmorillonite) Trefawey suitable for the nature of geological layers such as oil shale, limestone and sandstone. This means preparing drilling fluid using bentonite (montmorillonite) Trefawey to drill the above structures. The study has concluded that it is better to use bentonite (montmorillonite) Trefawey in preparing direct oil emulsions as a stable and successful alternative of imported bentonite.

A Short Review on skin cares Cream

In this article we studied in creams are topical preparation for the applied on the skin. “viscous liquid or semisolid emulsion is called as cream" The topical formulation is used to introduced the drug into the skin or mucous membrane of skin. And also for the different skin disorders. In this article we also discussed in the types of creams and there examples. Then studied the creams is pharmaceutical product because they prepared on the basis of technology in pharmaceutical industry. They may be medicated or non medicated or they are herbal, ayurvedic & allopathic. Skin reflects origins, lifestyle, age and state of health. Skin creams are mainly classified as O/W & W/O. Then they will be emmulsified by emulsifying agent. In the skin creams various vitamins are used like vit A, E, & D3 are the synthetic and fatty acid (EFA) are used. In which also used the water, oil, fat, Waxes, colours, glycol and etc. Creams have the number of advantages like easy apply, more effective compares to other avoid risk, drugs are absorb perfectly but in which disadvantages also present like, skin irritation can occur due to adjuent, large size drug are not absorb perfectly and etc.