thioredoxin h
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2022 ◽  
Author(s):  
Zhihao Jiang ◽  
Xuejiao Jin ◽  
Meng Yang ◽  
Qinglin Pi ◽  
Qing Cao ◽  
...  

Salicylic acid (SA) acts as a signaling molecule to perceive and defend against pathogen infections. Accordingly, pathogens evolve versatile strategies to disrupt the SA-mediated signal transduction. However, it is necessary to further characterize how plant viruses manipulate the SA-dependent defense responses. Here, we show that Barley stripe mosaic virus (BSMV) infection activates SA-mediated defense signaling pathway and upregulates the expression of Nicotiana benthamiana thioredoxin h-type 1 (NbTRXh1). The γb protein interacts directly with NbTRXh1 in vivo and in vitro. Overexpression of NbTRXh1, but not a reductase-defective mutant, impedes BSMV infection, whereas low NbTRXh1 expression level results in increased viral accumulation. Similar with its orthologues in Arabidopsis, NbTRXh1 also plays an essential role in SA signaling transduction in N. benthamiana. To counteract NbTRXh1-mediated defenses, the BSMV ?b protein targets NbTRXh1 to dampen its reductase activity and thereby impairing downstream SA defense genes expression to optimize viral cell-to-cell movement. We also found that NbTRXh1-mediated resistance defends against Lychnis ringspot virus, Beet black scorch virus, and Beet necrotic yellow vein virus. Taken together, our results reveal a novel role for the multifunctional γb protein in counteracting plant defense responses, and broadens the broad-spectrum antibiotic role of SA signaling pathway.


2021 ◽  
Vol 11 (15) ◽  
pp. 6865
Author(s):  
Eun Seon Lee ◽  
Joung Hun Park ◽  
Seong Dong Wi ◽  
Ho Byoung Chae ◽  
Seol Ki Paeng ◽  
...  

The thioredoxin-h (Trx-h) family of Arabidopsis thaliana comprises cytosolic disulfide reductases. However, the physiological function of Trx-h2, which contains an additional 19 amino acids at its N-terminus, remains unclear. In this study, we investigated the molecular function of Trx-h2 both in vitro and in vivo and found that Arabidopsis Trx-h2 overexpression (Trx-h2OE) lines showed significantly longer roots than wild-type plants under cold stress. Therefore, we further investigated the role of Trx-h2 under cold stress. Our results revealed that Trx-h2 functions as an RNA chaperone by melting misfolded and non-functional RNAs, and by facilitating their correct folding into active forms with native conformation. We showed that Trx-h2 binds to and efficiently melts nucleic acids (ssDNA, dsDNA, and RNA), and facilitates the export of mRNAs from the nucleus to the cytoplasm under cold stress. Moreover, overexpression of Trx-h2 increased the survival rate of the cold-sensitive E. coli BX04 cells under low temperature. Thus, our data show that Trx-h2 performs function as an RNA chaperone under cold stress, thus increasing plant cold tolerance.


Italus Hortus ◽  
2020 ◽  
Vol 27 (3) ◽  
pp. 31-40
Author(s):  
Anna Rana ◽  
Annalisa Imperato ◽  
Rosa Rao ◽  
Giandomenico Corrado

2019 ◽  
Vol 50 (1) ◽  
Author(s):  
Bi-ying Wang ◽  
Hui-qin Huang ◽  
Shuang Li ◽  
Ping Tang ◽  
Hao-fu Dai ◽  
...  

2018 ◽  
Vol 120 ◽  
pp. 2545-2551 ◽  
Author(s):  
Raheem Haddad ◽  
Reza Heidari-Japelaghi ◽  
Nadiya Eslami-Bojnourdi

2017 ◽  
Vol 22 (2) ◽  
pp. 129-135 ◽  
Author(s):  
Seong-Cheol Park ◽  
Young Jun Jung ◽  
Il Ryong Kim ◽  
Yongjae Lee ◽  
Young-Min Kim ◽  
...  

2016 ◽  
Vol 1864 (8) ◽  
pp. 974-982 ◽  
Author(s):  
Per Hägglund ◽  
Christine Finnie ◽  
Hiroyuki Yano ◽  
Azar Shahpiri ◽  
Bob B. Buchanan ◽  
...  
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