Composition of the gas-plasma phase in the radioactive graphite - water vapor system

In this work, the composition and thermophysical properties of the “Reactor graphite-H2O” system at temperatures from 2123 to 3223 K are calculated. It was found that the main components of the vapor phase at a temperature of 2123-2923 K: carbon dioxide, carbon monoxide, water vapor, hydroxide, hydrogen, atomic hydrogen. At temperatures above 3223 K, oxygen and atomic oxygen are added to the gases present. The balances of uranium and plutonium are considered. Uranium at temperatures above 2123 K is present in the system in the form of gaseous and ionized uranium dioxide and trioxide. Plutonium at temperatures above 2123 K is present in the system in the form of gaseous and ionized plutonium oxide, gaseous plutonium dioxide. The calculation of thermophysical properties for the considered system is carried out.

Ultrafast electron holes in plasma phase space dynamics

Electron holes (EH) are localized modes in plasma kinetic theory which appear as vortices in phase space. Earlier research on EH is based on the Schamel distribution function (df). A novel df is proposed here, generalizing the original Schamel df in a recursive manner. Nonlinear solutions obtained by kinetic simulations are presented, with velocities twice the electron thermal speed. Using 1D-1V kinetic simulations, their propagation characteristics are traced and their stability is established by studying their long-time evolution and their behavior through mutual collisions.

Antithrombin glycoforms from type II antithrombin deficient patients selectively adsorb onto the surface of plasma extracellular vesicles

AT is a glycoprotein produced by the liver and acts as the most important antagonist of clotting factors. A deficit in AT production or function leads to coagulation disorders. Two kinds of AT deficiencies are reported, named quantitative (or type I) and qualitative (or type II) defects. The first is characterized by low levels of AT in the bloodstream, the latter by impaired AT activity related to dysfunctional domains of AT and it is challenging to diagnose. Although being a soluble protein, evidence of AT transported by plasma EVs has been found but the physicochemical features of the association of AT to EVs are missing. We separated and characterized EVs from the plasma of healthy subjects, focusing on AT association. We found AT is localized on the external leaflet of the EV membrane. Furthermore, 2D-electrophoresis conducted on plasma and EVs of healthy subjects highlighted that specific AT glycoforms are selectively enriched onto the EVs with respect to whole plasma, suggesting that glycosylation plays a role in the partitioning of AT between the EV surface and liquid plasma phase, and ultimately on the EV exofacial topology. Finally, we separated EVs from the plasma of 8 patients affected by type II AT defect. The comparison of the AT 2D-electrophoretic pattern of patients and healthy subjects highlighted a difference in AT adsorption onto EV surface, supporting the role of EVs in coagulation and suggesting a promising approach to improve diagnosis and management of type II AT deficiencies.

Study and analysis of the coagulation factors and their natural inhibitors levels in apheresis derived platelet concentrate units over a five-day storage period

Background: The possibility of utilizing clotting factors in the plasma phase of apheresis platelet concentrates, as a supplement to the standard FFP transfusion for clotting factor replacement needs to be explored. In this study, it was proposed to assess the effect of storage on clotting factors and inhibitors in stored apheresis platelet concentrates. This would give an insight into the hemostatic potential of the plasma phase of the apheresis platelet concentrates.Methods: This study was conducted on a sample size of 45 apheresis platelet concentrate units harvested on Amicus cell separator. Basic coagulation workup along with various coagulation factors and their natural inhibitors were studied in the apheresis platelet concentrates on day ‘0’ and day ‘5’ of the collection.Results: Prothrombin time and activated partial thromboplastin time of the apheresis platelet concentrates was increased on day ‘5’ of the collection but were within the normal range. Fibrinogen, Factor XII, and VWF: Ag showed an increase on day ‘5’ of collection. Protein C, protein S activity, and antithrombin decreased on day ‘5’ of collection. Also, Factors II, VII, IX, X, XI decreased on day ‘5’. The highest fall in activity was seen in the case of Factors V and VIII. Despite the fall, all the clotting factors were maintained within their normal range.Conclusions: Although the activity of most of the coagulation factors showed a decrease, it was maintained within their normal range and efficacy. Therefore, a reasonable hemostatic potential of the clotting factors is expected to be maintained in apheresis platelet concentrates after a storage period of five days at room temperature.

Theoretical Study of the Photons Production Kinetic In Hot Quark-Gluon Plasma Matter

In this paper, we study flow of photons rate production in a quark-gluon QG plasma. General theory of this study is based on the field theory for hard interaction. The kinetic of photons production from hard interaction in charm with anti-top to production photons with gluon due to plasma phase at high temperatures (150, 200,250,300 and 350 MeV) .It has been investigated and studied using the postulate of quantum chromodynamic theory QCD .The photons production rate of hard photons with( GeV) are insensitive to strength coupling and depend mainly on the temperature of system T . Despite the different critical temperature (150 and 190MeV) comes, we find that same order of flow rate photons magnitude in both cases. In both cases, the flow rate of photons production in the QG plasmais increased with increased temperature of system and photons energy and decreases with increases the strength coupling strength.