Investigation of factors of the appearance of odor in river water at the water intake of Rostov-On-Don

The paper presents a study of quality of natural waters and water in a centralized water supply system during the period of an increase in the “Smell” indicator in the spring of 2021. The chemical and physical properties of water, the results of quality and quantity of studying the variety I phytoplankton in the most difficult period of deterioration in quality of river water. Low water and exceeding MPC concentrations of organic substances in river water. The Don River causes altered form odorant substance as evidenced by the results of determination in water 1,2,3- t rihlorbenzol and geosmin, hexachloroethane and aniline shown in operation. Barrier function of reagent treatment methods used at water treatment plants in the lower reaches of the river. The Don River, even when combined with carbonated water, is deficient in odor-producing substances.

Modulating amygdala activation to traumatic memories with a single ketamine infusion

NMDA receptor antagonists have a vital role in extinction, learning, and reconsolidation processes. During the reconsolidation window, memories are activated into a labile state and can be stored in an altered form. This concept might have significant clinical implications in treating PTSD. Using amygdala activity as a major biomarker of fear response, we tested the potential of a single subanesthetic intravenous infusion of ketamine (NMDA receptor antagonist) to enhance post-retrieval extinction of PTSD trauma memories. Post-extinction, ketamine recipients (vs midazolam) showed a lower amygdala and hippocampus reactivation to trauma memories. Post-retrieval ketamine administration was also associated with decreased connectivity between the amygdala and hippocampus, with no change in amygdala-vmPFC connectivity, which suggests that ketamine may enhance post-retrieval extinction of PTSD trauma memory in humans. These findings demonstrate the capacity to rewrite human traumatic memories and to modulate the fear response for at least 30 days post-extinction.

THE MOTIF OF THE PRODIGAL SON IN THE PLOT OF IVAN BUNIN’S NOVEL THE LIFE OF ARSENIEV

The article is devoted to the research of the reception and transformation of the subject of the Gospel Parable of the Prodigal Son in the novel The Life of Arseniev by Ivan Bunin. The key events in the Parable of the Prodigal Son are present in the structure of The Life of Arseniev: leaving the ancestral home — leaving God behind; temptations of the spirit and flesh, dissolute life, spiritual lust, spiritual death; confession; return to the ancestral home — return to God, to the Heavenly Father’s Home. Arseniev's departure from his ancestral home differs from the departure of the Gospel Parable’s hero, yet this event is one of the landmarks in the main character’s life path of life. Unlike the prodigal son, Aleksey Arseniev leaves his home seeking the highest meaning and purpose of life as the key aim; the sense of God’s presence had been present in his soul since his very childhood. However, the youthful thirst for glory and pleasures of life led Bunin's hero to the abandonment of the Heavenly Father and to immersion in sinful life. The tropes of sensuality, temptation, desire, degradation, sins, unfaithfulness, adultery are the key motifs in the description of the hero’s dissolute life. Arsenyev’s immoral life became the main reason for the damage to his relationship with Lika and her breakup with him. The most important events in the Gospel Parable of the Prodigal Son are repentance of sins, penance before his father and before God — these events appear in Bunin’s novel in an altered form. Since Arseniev did not experience deep repentance before God for his sinful youth, the resurrection of his soul and his return to the Home of the Heavenly Father were impossible. Bunin demonstrates that an entire life is required for the hero to experience true repentance and his final return to God, thus Bunin leaves Arseniev on the path to God. Scenes from the Gospel Parable of the Prodigal Son, such as departure from the ancestral home, dissolute life and spiritual death are recreated most completely in Bunin’s novel The Life of Arseniev; while repentance and return to God, which take up the remainder of the hero’s life, are described by the author in a complex altered form.

PITTAJA ARTAVADUSHTI AND ITS TREATMENT: A CASE STUDY

In order to give rise to new offspring, female body undergoes menstrual cycle. It involves the shedding of endometrium manifested as Māsānumāsika Rajaḥ Pravṛtti i.e., Ārtava Pravṛtti. Due to changes in life style of women in terms of Āhāra, Vihāra, there is more physical and emotional stress and this may result in Ārtavaduṣṭi, where the normal menstrual cycle gets disturbed or presented in altered form. Background: A married Hindu female patient of 35 years came to NIA Prasuti-stree Roga OPD on 25th July, 2019 with complaints of painful menstruation since last 14 years, heavy bleeding during menstruation since last 10 years and mild burning micturition with increased frequency of micturition (on/off) since last 2 years. Methodology: Mainly Pitta Doṣa vitiation symptoms were observed in the patient. Her complete Nidāna Parivarjana and Prakṛti Vighāta was done and Pitta Doṣa Śāmaka Dravyas were used in treatment including specific Pittaja Ārtavaduṣṭi line of treatment mentioned in Ayurvedic classics. She was given combination of Yaṣṭīmadhu Cūrṇa, Miśi (Fennel), Munakkā (dried Vitis vinifera), Goghṛta twice a day in the form of Kalka with warm water, Kuṭakī Cūrṇa, Munakkā, Dhāgā Miśrī in equal parts in the form of pea sized Guṭikā twice a day with cold water, Gokṣura Cūrṇa, Copcīnī Cūrṇa twice a day with water, Avipattikara Cūrṇa before meal, twice a day with water. The treatment was continued for 2 months. Result: There was relief in menstrual and urinary symptoms after 2 months of treatment.

ON THE CHANGE OF VALUES OF POSTNOMINATIVE APPENDICES IN THE PROCESS OF TRANSFORMATION IN THE MODERN ENGLISH

Article deals with the changes of the meanings of the post nominal adjectives in the process of transformation in the modern English language. On the basis of the linguoculturological approach and the method of linguistic analysis, the characteristic features of the change in the meanings of post-nominative adjectives in the English language have been revealed. In the English language the adjectives can perform the function of predicative. For the semantics of the adjectives which have the predicative function, these adjectives are characterized by inner qualitative diversity. Mainly, qualitative adjectives refer to classical predication and denote the feature of the object directly. Such adjectives have more features of predication. The predicative sign of the adjective, the presence of a connotation of subjective assessment determines its semantics and use. There are differences between the constructions used in the predicate function in phrases that perform the function of the subject and in the altered form of word phrases related attributively and predicatively. The predicative relation is the immunest form of syntactic connection and in predicative connectives the structural restriction in comparison with attributive constructions is extremely limited. Adjectives as predicative words do not have denotation and reference, they have no denoter, there is a signification. Basing on their indicative characteristics, it is possible to present all the possible semantic features. For the English language it is characteristic the use of the attribute before the defined word. The development from a special sign of thought to a general concept is characteristic for the whole structure of the English language; it is even possible to observe it in word formation. In most cases, taking into account the use of the adjective in the function of an attribute, the terms like postpositional (post nominal) and prepositional (prenominal) adjectives are used. The reasons for the change in the position of adjectives should be sought not always in the nature of the adjective, but in the degree to which it determines its referent. The semes that make up the meaning of the word are at different levels and are more or less stable. In adjectives, the nuclear seme, or subseme, is always found next to the differential seme. In other words, the adjective cannot be combined with nouns in all semantic groups. When an adjective is combined with a noun, a background is formed that allows or prevents the actualization of a particular seme. This causes the activation of a specific seme associated with the semantics of the given name in combination with the given name. Such semes are reflected in the join semantics. The opposite can also be said. The adjective itself chooses the noun for word formation. After all, the same adjective behaves differently in relation to transformation into different attributive complexes. In our opinion, adjectives act as an important restrictive informative element at the content level.

“New Kids on the Block?” Reappraising Pottery Styles, aDNA, and Chronology from Western Iberia Early Neolithic

Western Iberia Early Neolithic has been described as an ultimate and very altered form of the Mediterranean Neolithisation process. Despite its Atlantic position, this territory – corresponding mainly to Central/Southern Portugal – is, in its physical and cultural geography, a Mediterranean landscape deeply connected to a historical process arriving from beyond the Strait of Gibraltar. The presence of cardial pottery led archaeologists to ascribe Portuguese Early Neolithic to a Mediterranean impressed Pottery cultural area, and according to demic diffusion models, small pioneer groups carrying the Neolithic package originated there. Recently, the archaeological record for the Western Mediterranean Neolithisation is becoming more complex and longer lasting cardial dominance over the seas has been disputed. Previous Neolithic groups seafaring the Mediterranean coasts with Impressa style pottery could have reached Iberian Peninsula by 5600–5400 cal BC, proving that by the mid-sixth millennium, different cultural entities were moving in the Western Mediterranean regardless of their genetic features. The main goal of this study is to disclose this cultural diversity in Western Iberia using a robust chronological database and debating how different proxies, like pottery styles and ancient DNA (aDNA), reveal it in Western Iberia. While recognising the Mediterranean input to Western Iberia groups, mapping the variability and the significance of different decoration techniques, such as cardial, false acacia leaf, impressed stripes, and using the aDNA to identify continuities/changes in ancient populations are here as tools to understand when, who, and how new kids came to the block. To do so, different disciplinary boundaries are crossed, and some transdisciplinary critical aspects are also commented.

Between Tradition and Innovation : the sepulchral monument of Adam Easton at S. Cecilia in Trastevere

This chapter discusses the original setting, appearance and authorship of the sepulchral monument of Cardinal Adam Easton, which survives in considerably reduced form in the church of S. Cecilia in Trastevere, Rome. A re-examination of both visual and written sources, including a muchdebated drawing of the tomb in an already partially altered form, leads to new hypotheses about the original location, appearance and significance of the monument within the sacred topography of the church. Renewed visual and technical analysis will shed new light on the commission and its artists. Parallels are also drawn with the tomb of Cardinal Philippe d’Alençon in S. Maria in Trastevere in order to think about ‘portraiture’ in late-Trecento Rome. The reconstructed original tomb, alongside the extant effigy, bier and laudatory inscription, are then used to offer further insights into the life of Easton, his supporters and his desire for perpetual remembrance.

Unconventional immunotherapy with an unconventional target

Pritumumab, a natural human IgG1 kappa antibody was obtained from a regional draining lymph node of a patient with cervical carcinoma through traditional hybridoma technology. Specificity analysis of the target antigen, an altered form of vimentin called, ecto-domain vimentin (EDV), shows it to be limited to cell surface expression on cancer cells. Clinically, 249 brain cancer patients were treated with a low dose pritumumab regimen, either at 1 mg once a week or 1 mg twice a week, and of those evaluated overall response rates of between 25–30% were seen with several complete and partial responses. A clinical trial assessing higher doses of pritumumab as a therapeutic for brain cancer is expected to begin this year. Overall, these data together suggest pritumumab is suitable for further development as an anti-tumor therapeutic.

Online celebrity discourses on Facebook

The web 2.0 phenomenon and social media – without question – have reshaped our everyday experiences. These changes that they have generated affect how we consume, communicate and present ourselves, just to name a few aspects of life, and moreover, opened up new perspectives for sociology. Though many social practices persist in a somewhat altered form, brand new types of entities have emerged on different social media platforms: one of them is the video blogger. These actors have gained great visibility through so-called micro-celebrity practices and have become potential large-scale distributors of ideas, values and knowledge. Celebrities, in this case micro-celebrities (video bloggers), may disseminate such cognitive patterns through their constructed discourse which is objectified in the online space through a peculiar digital face (a social media profile) where fans can react, share and comment according to the affordances of the digital space. Most importantly, all of these interactions are accessible for scholars to examine the fan and celebrity practices of our era. This research attempts to reconstruct these discursive interactions on the Facebook pages of ten top Hungarian video bloggers. All findings are based on a large-scale data collection using the Netvizz application. As part of the interpretation of the results, a further consideration was that celebrity discourses may be a sort of disciplinary force in (post)modern society, which normalizes the individual to some extent by providing adequate schemas of attitude, mentality and ways of consumption.

PRÍONS E DOENÇAS PRIÔNICAS: UMA REVISÃO

The name príon is given to an altered form of a protein present at the surface of neurons. Prions are remarkable for been able to induct their normal counterpart to assume the pathological configuration on a kind of chain reaction, with the possibility of trasmission between subjects and even through different species. Prions can cause a series of neurodegenerative disorders affecting humans (Creutzfeldt-Jakob disease, Gerstmann-Straussler-Scheinker syndrome, fatal familial insomnia, kuru), and animals such cattle (bovine spongiform encephalopathy or “mad cow disease”), deer (chronic wasting disease) and sheep (scrapie). This article is a non-systematic review, obtained on PubMed, SciELO and Google Scholar databases, with the aim to give a general view about the nature of prions, followed by a brief discussion of the human diseases caused by prions.