A case of reactivation of hepatitis B presenting with exudative ascites

Hepatitis B virus infection is a global problem and causes several liver diseases including acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Though uncommon, some immune mediated extra-hepatic manifestations may develop during the infection. Exudative ascites during HBV infection is one such.

Assessment of Hepatitis C virus genotypes in regular dialysis patients of Khyber Pakhtunkhwa, Pakistan

Globally viral hepatitis is a major health problem. HCV is a causative agent of hepatitis and is responsible for acute and chronic hepatitis leads to cirrhosis and hepatocellular carcinoma. This study was carried out to know the HCV genotypes in Dialysis patients in NWFP (Pakistan). The age ranged from 15-65 years. During this study a total of 63 samples were collected and were analyzed for HCV genotypes. RNA was extracted from whole blood; reverse transcribed into cDNA and was subjected to multiplex PCR. Of these 63 samples, 14 were genotyped as genotype 3a was found in 9(64.28%) patients, followed by genotype 3b (21.42%) in 3 and 2a in 2(14.28%) patients. Three positive samples remained untyped. In age group 31 to 40 years, the number of positive patients were comparatively greater.

Autoimmiune Hepatitis in Children: Two Case Report

Autoimmune hepatitis (AIH) is the disease of immune mediated inflammation of liver. Presentation of AIH in children is variable, ranging from acute hepatitis to cirrhosis of liver and also as only asymptomatic raised ALT. AIH can present at any age and female are more affected. Here we are presenting two cases. Case 1 presented with jaundice and H/O epistaxis, having cutaneous echymosis, hepato-splenomegaly and ascites. Case 2 was a diagnosed case of Systemic Lupus Erythematosus (SLE) presented with only persistent raised of serum ALT. Both were diagnosed as autoimmune hepatitis on the basis of positive auto antibodies, histopathology of liver tissues and exclusion of all other causes of acute and chronic hepatitis. Bangladesh Med J. 2020 Jan; 49 (1): 45-50