ethanol injection method
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2019 ◽  
Vol 18 (1) ◽  
pp. 103-111 ◽  
Author(s):  
Sayani Bhattacharyya ◽  
Bharani S Sogali

In the present study custom screening design was employed to observe the effect of four critical process parameters on particle size and polydispersity index of the liposomal formulation made by ethanol injection method. The four process parameters selected were lipid ratio, rate of injection, phase volume ratio and rotational speed of magnetic stirring. Eight different liposomal formulations were prepared using the design. The formulations were subjected to particle size analysis. The analysis was done at a significance level p<0.05 and found that the process parameters had significant effect on the particle size and polydispersity index of the formulations. The design was optimized for the individual responses with an overall desirability of more than 50%. Three batches of liposomes were formulated at optimized process parameters which matched the target as predicted by the design. Therefore, it can be concluded that the design was effective in production of nano sized stable monodisperse liposomes by ethanol injection method. Dhaka Univ. J. Pharm. Sci. 18(1): 103-111, 2019 (June)


2017 ◽  
Vol 12 (5) ◽  
pp. 346 ◽  
Author(s):  
Sherif Shaker ◽  
AhmedRifaat Gardouh ◽  
MamdouhMostafa Ghorab

2016 ◽  
Vol 15 ◽  
pp. 1-10 ◽  
Author(s):  
Carine Sebaaly ◽  
Hélène Greige-Gerges ◽  
Serge Stainmesse ◽  
Hatem Fessi ◽  
Catherine Charcosset

2016 ◽  
Vol 27 (4) ◽  
pp. 249-263 ◽  
Author(s):  
Micaela Tamara Vitor ◽  
Patrícia Cruz Bergami-Santos ◽  
Rafael Henrique Freitas Zômpero ◽  
Karen Steponavicius Piedade Cruz ◽  
Mariana Pereira Pinho ◽  
...  

2015 ◽  
Vol 94 ◽  
pp. 508-515 ◽  
Author(s):  
Catherine Charcosset ◽  
Audrey Juban ◽  
Jean-Pierre Valour ◽  
Sébastien Urbaniak ◽  
Hatem Fessi

2013 ◽  
Vol 61 (46) ◽  
pp. 11119-11126 ◽  
Author(s):  
Gye Hwa Shin ◽  
Seoung Kyun Chung ◽  
Jun Tae Kim ◽  
Hee Joung Joung ◽  
Hyun Jin Park

2009 ◽  
Vol 20 (3) ◽  
pp. 228-243 ◽  
Author(s):  
Chiraz Jaafar-Maalej ◽  
Roudayna Diab ◽  
Véronique Andrieu ◽  
Abdelhamid Elaissari ◽  
Hatem Fessi

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