Spyglass Ds
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2021 ◽  
Vol 32 (5) ◽  
pp. S94-S95
J. Xu ◽  
M. Darcy ◽  
D. Picus ◽  
N.B. Mani ◽  
J. Marlow ◽  

Endoscopy ◽  
2021 ◽  
Lingjian Kong ◽  
Dan Liu ◽  
Jiyu Zhang ◽  
Ullah Saif ◽  
Lixia Zhao ◽  

Objective: To investigate the diagnostic and therapeutic value of the SpyGlass DS (single-operator cholangioscopy system) for endoscopic management of acute appendicitis. Methods: Fourteen patients with acute uncomplicated simple or supportive appendicitis were evaluated between November 2018 and September 2020. The diagnosis of acute appendicitis was confirmed by colonoscopy direct vision imaging and Spyglass imaging. The successful rate of the Spy-Glass DS assisted endoscopic retrograde appendicitis therapy, the procedure time, post-operative length of hospital stay, complications, and recurrence rate were recorded Results: The procedure technical success rate was 100% with high quality imaging of the appendiceal cavity of all 14 patients using SpyGlass DS. The average procedure time was 37.8 ± 22 min. Abdominal pain was relieved immediately after the procedure in all patients. The average post-operative hospital was 1.9 ± 0.7 days. No recurrence occurred during 2 to 24 months of follow-up. Conclusion: Spyglass-assisted endoscopic retrograde appendicitis therapy provides a feasible, safe, effective alternative approach to diagnose and management of acute uncomplicated appendicitis without the need for X-ray or ultrasonic guidance.  

2021 ◽  
Vol 60 (1) ◽  
pp. 47-52
Katsuyuki Miyabe ◽  
Kenji Notohara ◽  
Go Asano ◽  
Akihisa Kato ◽  
Naruomi Jinno ◽  

2020 ◽  
Vol 52 ◽  
pp. S182-S183
R. Gabbiadini ◽  
A. Fugazza ◽  
M. Colombo ◽  
S. Carrara ◽  
R. Maselli ◽  

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 666
Li-Jia Wen ◽  
Jun-Hong Chen ◽  
Hong-Ji Xu ◽  
Qiong Yu ◽  
Kai Liu

Background: Biliary strictures are frequently encountered in clinical practice. The determination of their nature is often difficult. This study aims to systematically evaluate the efficacy and safety of the second generation of digital single-operator cholangioscopy (SpyGlass DS, DSOC) in indeterminate biliary strictures (IBDS) through biopsies. Methods: All relative studies published in Medline, the Cochrane Library, Web of Science, and EMBASE were included. The diagnostic tests for IBDS were compared to the surgical histology, autopsy, or long-term clinical follow-up. The methodological quality of the included studies was evaluated by the Quality Assessment of Studies of Diagnostic Accuracy Included in Systematic Reviews (QUADAS-2). Results: A total of 11 studies, which involved 356 patients diagnosed through biopsies, were included. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio were 0.74 (95% CI: 0.67–0.80), 0.98 (95% CI: 0.95–1.00), 10.52 (95% CI: 5.45–20.32), 0.31 (95% CI: 0.23–0.41), and 65.18 (95% CI: 26.79–158.61), respectively. The area under the curve (AUC) was 0.9479, and the pooled adverse event rate was 7%. The sensitivity and specificity in the heterogeneity analysis were I2 = 48.1% and I2 = 25.4%, respectively. Conclusion: SpyGlass DS is a safe and effective technique for IBDS. However, future randomized trials are needed to determine optimal number of biopsies.

2020 ◽  
Vol 59 (16) ◽  
pp. 1925-1930
Toji Murabayashi ◽  
Takahisa Ogawa ◽  
Shinsuke Koshita ◽  
Yoshihide Kanno ◽  
Hiroaki Kusunose ◽  

Lijia Wen ◽  
Junhong Chen ◽  
Liang Guo ◽  
Kai Liu

Castleman disease (CD) rarely presents with obstructive jaundice, which poses a diagnostic and therapeutic challenge to the management of the disease. A 40-year-old man was referred to our hospital for emergent management of upper abdominal pain. An abdominal mass was removed, and the postoperative pathology showed retroperitoneum CD, which was subsequently managed by adjuvant therapy of combination chemotherapy and steroids. One month later, a biliary metal stent was placed due to the presentation of obstructive jaundice. After approximately 3 months, the patient experienced another episode of obstructive jaundice, and SpyGlass DS cholangioscopy (Boston Scientific, Natick, Mass, USA) was performed via the biliary track for biopsy, which pathologically showed biliary malignancies. Radiofrequency ablation was performed with a probe (EMcision, Montreal, Canada), and another uncovered metal stent was placed within the existing metal stent. No stent occlusion occurred during a 6-month follow-up period. In conclusion, CD rarely presents with obstructive jaundice, and a combination of radiofrequency ablation with metal stent implantation under cholangioscopy can prolong the stent patency time and the survival time of patients.

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