control variation
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2021 ◽  
Vol 10 ◽  
Author(s):  
Peter W H Holland ◽  
Chris D Jiggins ◽  
Miriam Liedvogel ◽  
Graham Warren ◽  
Yannick Wurm

Supergenes are regions of suppressed recombination that may span hundreds of genes and can control variation in key ecological phenotypes. Since genetic analysis is made impossible by the absence of recombination between genes, it has been difficult to establish how individual genes within these regions contribute to supergene-controlled phenotypes. The white-throated sparrow is a classic example in which a supergene controls behavioral differences as well as distinct coloration that determines mate choice. A landmark study now demonstrates that differences between supergene variants in the promoter sequences of a hormone receptor gene change its expression and control changes in behavior. To unambiguously establish the link between genotype and phenotype, the authors used antisense oligonucleotides to alter the level of gene expression in a focal brain region targeted through a cannula. The study showcases a powerful approach to the functional genomic manipulation of a wild vertebrate species.


Entropy ◽  
2020 ◽  
Vol 22 (10) ◽  
pp. 1076 ◽  
Author(s):  
Paolo Abiuso ◽  
Harry J. D. Miller ◽  
Martí Perarnau-Llobet ◽  
Matteo Scandi

Differential geometry offers a powerful framework for optimising and characterising finite-time thermodynamic processes, both classical and quantum. Here, we start by a pedagogical introduction to the notion of thermodynamic length. We review and connect different frameworks where it emerges in the quantum regime: adiabatically driven closed systems, time-dependent Lindblad master equations, and discrete processes. A geometric lower bound on entropy production in finite-time is then presented, which represents a quantum generalisation of the original classical bound. Following this, we review and develop some general principles for the optimisation of thermodynamic processes in the linear-response regime. These include constant speed of control variation according to the thermodynamic metric, absence of quantum coherence, and optimality of small cycles around the point of maximal ratio between heat capacity and relaxation time for Carnot engines.


2020 ◽  
Vol 16 (4) ◽  
pp. 1663-1683
Author(s):  
Ying Zhang ◽  
◽  
Changjun Yu ◽  
Yingtao Xu ◽  
Yanqin Bai ◽  
...  

2019 ◽  
Vol 11 (3) ◽  
pp. 66
Author(s):  
Clodoaldo Valverde ◽  
Basilio Baseia

In the present work, we theoretically study the entropy of a Cooper pair box coupled to a one-dimensional transmission line resonator. The proposed scheme uses the Jaynes-Cummings model in presence of losses to study the time avolution of the system entropy. The coupling of these two subsystems provides an important indication of the influence of Cooper pair box on the evolution of system entropy. Decaying CPB allows us to control variation of entropy at certain times.


Author(s):  
Humberto Valadez Rangel ◽  
Alexander G. Loukianov ◽  
B. Castillo-Toledo ◽  
Eduardo Bayro-Corrochano

Automatica ◽  
2013 ◽  
Vol 49 (9) ◽  
pp. 2652-2664 ◽  
Author(s):  
Ryan Loxton ◽  
Qun Lin ◽  
Kok Lay Teo

2011 ◽  
Vol 7 (1) ◽  
pp. 016006 ◽  
Author(s):  
Sebastian Riese ◽  
Andre Seyfarth
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