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2021 ◽  
Vol 1 (3) ◽  
pp. 95-101
Author(s):  
Burcu İleri Fikri ◽  
Ezgi Direnç Kulunk ◽  
Güldem Turan

2021 ◽  
Vol 12 ◽  
Author(s):  
Jinghao Li ◽  
Senhui Weng ◽  
Sen Lin ◽  
Linwen Huang ◽  
Xiaojun Yang ◽  
...  

Introduction: The quantitative myasthenia gravis score is a commonly used scale for evaluating muscle weakness associated with myasthenia gravis (MG). It has been reported that some items used in the scale have low discriminative properties. However, there has been no research investigating the applicability of the quantitative MG score (QMGS) in Chinese patients with MG. In addition, the scoring method and ranges of grip strength items in QMGS need to be further evaluated.Methods: This study included 106 Chinese patients with MG, enrolled between September 2020 and February 2021, who were evaluated using the QMGS. Each item in the QMGS was analyzed for distribution. Three methods of evaluating grip strength, grip strength decrement, maximum grip strength, and relative grip strength, were compared. The correlation between the QMG total score minus grip strength score, and three evaluating methods, was analyzed.Results: The grip strength, swallowing, speech, diplopia, ptosis, and facial muscles items showed a clustered distribution. Most patients (94%) presented their maximum grip strength in the first four grip strength measurements. The QMG total score minus the grip strength score had a weak correlation with grip strength decrement (R grip r = 0.276; L grip r = 0.353, both p < 0.05) and moderate correlations with maximum grip strength (R grip r = −0.508; L grip r = −0.507; both p < 0.001) and relative grip strength (R grip r = −0.494; L grip r = −0.497, both p < 0.001).Conclusions: This study suggested that partial items in the QMGS have low discriminative properties for Chinese populations and the maximum grip strength value is the better method to evaluate grip strength compared to the other two scoring methods. Based on the quartiles of maximum grip strength, we propose new scoring ranges for the grip strength items.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Masahiro Shirata ◽  
Isao Ito ◽  
Tadashi Ishida ◽  
Hiromasa Tachibana ◽  
Naoya Tanabe ◽  
...  

AbstractThe discriminative power of CURB-65 for mortality in community-acquired pneumonia (CAP) is suspected to decrease with age. However, a useful prognostic prediction model for older patients with CAP has not been established. This study aimed to develop and validate a new scoring system for predicting mortality in older patients with CAP. We recruited two prospective cohorts including patients aged ≥ 65 years and hospitalized with CAP. In the derivation (n = 872) and validation cohorts (n = 1,158), the average age was 82.0 and 80.6 years and the 30-day mortality rate was 7.6% (n = 66) and 7.4% (n = 86), respectively. A new scoring system was developed based on factors associated with 30-day mortality, identified by multivariate analysis in the derivation cohort. This scoring system named CHUBA comprised five variables: confusion, hypoxemia (SpO2 ≤ 90% or PaO2 ≤ 60 mmHg), blood urea nitrogen ≥ 30 mg/dL, bedridden state, and serum albumin level ≤ 3.0 g/dL. With regard to 30-day mortality, the area under the receiver operating characteristic curve for CURB-65 and CHUBA was 0.672 (95% confidence interval, 0.607–0.732) and 0.809 (95% confidence interval, 0.751–0.856; P < 0.001), respectively. The effectiveness of CHUBA was statistically confirmed in the external validation cohort. In conclusion, a simpler novel scoring system, CHUBA, was established for predicting mortality in older patients with CAP.


Author(s):  
William R. Koski ◽  
Brent G Young

Effective management of animal populations requires knowledge of life history parameters and estimates of population abundance. One method commonly used to estimate abundance is capture/recapture analyses of photographs. Small, relatively inexpensive, rotary-wing drones have become an effective platform for obtaining high-quality aerial photographs of whales. To conduct capture/recapture analyses the animal needs to be defined as marked or unmarked and the photographs must be of high quality. While a system for scoring quality and markedness has previously been developed for bowhead whales (Balaena mysticetus) (Rugh et al. 1998), a revised scoring system was needed to incorporate increased information in photographs taken by drones. We present a revised scoring system that enlarges two of the previously defined areas of the whale examined for markings and incorporates smaller markings into the definition of marked whales. We scored 30 whales using the previous criteria and the revised criteria developed in this paper. More whales were identified as marked (23%) and mark scores were higher for 30% of the zones scored using the new system. Increasing the number of marked whales during capture/recapture studies increases the precision of estimated parameters and permits us to make those estimates with smaller samples of photographs.


2021 ◽  
Vol 267 ◽  
pp. 350-357
Author(s):  
Teppei Kamada ◽  
Eisaku Ito ◽  
Hironori Ohdaira ◽  
Junji Takahashi ◽  
Hideyuki Takeuchi ◽  
...  

2021 ◽  
Vol 8 (5) ◽  
pp. 37
Author(s):  
Michael Freunek ◽  
André Bodmer

In this paper we present a method to concatenate patent claims to their own description. By applying this method, bidirectional encoder representations from transformers (BERT) train suitable descriptions for claims. Such a trained BERT could be able to identify novelty relevant descriptions for patents. In addition, we introduce a new scoring scheme: relevance score or novelty score to interprete the output of BERT. We test the method on patent applications by training BERT on the first claims of patents and corresponding descriptions. The output is processed according to the relevance score and the results compared with the cited X documents in the search reports. The test shows that BERT score some of the cited X documents as highly relevant.


2021 ◽  
Vol 8 (24) ◽  
pp. 297-301
Author(s):  
Jonas Brehmer

Proper scoring rules enable decision-theoretically principled comparisons of probabilistic forecasts. New scoring rules can be constructed by identifying the predictive distribution with an element of a parametric family and then applying a known scoring rule. We introduce a condition which ensures propriety in this construction and thereby obtain novel proper scoring rules.


PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0257738
Author(s):  
Claudia Picard-Deland ◽  
Tore Nielsen ◽  
Michelle Carr

The phenomenon of dreaming about the laboratory when participating in a sleep study is common. The content of such dreams draws upon episodic memory fragments of the participant’s lab experience, generally, experimenters, electrodes, the lab setting, and experimental tasks. However, as common as such dreams are, they have rarely been given a thorough quantitative or qualitative treatment. Here we assessed 528 dreams (N = 343 participants) collected in a Montreal sleep lab to 1) evaluate state and trait factors related to such dreams, and 2) investigate the phenomenology of lab incorporations using a new scoring system. Lab incorporations occurred in over a third (35.8%) of all dreams and were especially likely to occur in REM sleep (44.2%) or from morning naps (48.4%). They tended to be related to higher depression scores, but not to sex, nightmare-proneness or anxiety. Common themes associated with lab incorporation were: Meta-dreaming, including lucid dreams and false awakenings (40.7%), Sensory incorporations (27%), Wayfinding to, from or within the lab (24.3%), Sleep as performance (19.6%), Friends/Family in the lab (15.9%) and Being an object of observation (12.2%). Finally, 31.7% of the lab incorporation dreams included relative projections into a near future (e.g., the experiment having been completed), but very few projections into the past (2.6%). Results clarify sleep stage and sleep timing factors associated with dreamed lab incorporations. Phenomenological findings further reveal both the typical and unique ways in which lab memory elements are incorporated de novo into dreaming. Identified themes point to frequent social and skillful dream scenarios that entail monitoring of one’s current state (in the lab) and projection of the self into dream environments elaborated around local space and time. The findings have implications for understanding fundamental dream formation mechanisms but also for appreciating both the advantages and methodological pitfalls of conducting laboratory-based dream collection.


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