real time ultrasonography
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2021 ◽  
Vol 14 (2) ◽  
pp. 30-41
Author(s):  
Rozh Muhammad ◽  
Dhafer Aziz

The study was aimed to estimate the gestational age of Shami does by transabdominal ultrasonographic measurement of maternal parameters. Thirty-three Shami does aged 2-2.5 years with confirmed conception dates were used. The does were examined in a standing position using a transabdominal 3.5 MHz convex sector probe of real-time ultrasonography. The does were examined weekly starting from 21 days of pregnancy until parturition. Measurements of the maternal parameters that include; the uterine diameter, placental width, and placental height were obtained from the ultrasonographic images using the software Screen Calipers. Results showed that the gestational sac and embryos were observed early on 21 and 35 days of pregnancy. The litter size of Shami does was 2-3 kids. Uterine diameter ranged between 27±1.4 and 136.9±4.2 mm between 21-130 days, placentomes width was 17.6±0.6 – 38.5±2.1 mm, placentomes height was 9.5 ± 1.8 – 24.5 ± 1.4 mm on 51-150 days of gestation. The highest positive correlations were obtained between the gestational age and the measurements of uterine diameter (r=0.943). The least positive correlations were between the gestational age and the values of placenta width (r=0.715) and placentom height (r=0.615). In conclusion, transabdominal ultrasonography is a practical method for pregnancy diagnosis and monitoring of embryo in Shami goats. Also, it is reliable to estimate gestation age from 21 days of pregnancy. The uterine diameter was the best maternal parameter that can be used for the longest period for estimation of Shami goats gestational age.


2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 351.2-352
Author(s):  
L. Van de Stadt ◽  
F. Kroon ◽  
M. Reijnierse ◽  
D. Van der Heijde ◽  
F. Rosendaal ◽  
...  

Background:Ultrasound (US) is used in rheumatic musculoskeletal diseases (RMDs) such as hand osteoarthritis (OA) as outcome measure. Traditionally scoring is performed real-time, but central reading of static US images could avoid issues of inter-rater reliability. However, agreement between real-time and static assessment has not been studiedObjectives:To study the agreement between real-time and static scoring of US in inflammatory hand OA.Methods:Ultrasound was performed of 30 joints obtained in 75 patients with hand osteoarthritis, treated with prednisolone or placebo in a randomized double-blind trial. Hand joints were assessed for synovial thickening, effusion, Doppler signal and osteophytes by ultrasound (score 0-3 per joint) at baseline and after treatment. Two ultrasonographers blinded for clinical data scored the live images together (simultaneously) in real-time. A consensus score for each joint was recorded. Representative images stored during scanning were scored by one ultrasonographer minimally 6 months after real-time scoring. For each patient, images of each visit were scored paired, with known chronological order.Agreement between scoring methods was studied at joint level with quadratic weighted kappa. At patient level, intra-class correlations (ICC; mixed effect model, absolute agreement, with clustering taken into account) were calculated at both timepoints. ICCs were also calculated for the delta of sum scores. Responsiveness of scoring methods was analyzed with generalized estimating equations (GEE) with treatment as independent and ultrasonography findings as dependent variable.Results:Thirty-nine patients (52%) were treated with prednisolone and 36 (48%) were treated with placebo. Patient characteristics were well-balanced between treatment groups.All patients had signs of synovial thickening and osteophytes as assessed by real-time ultrasonography, and almost all signs of effusion (99%) or a positive Doppler signal (95%) in at least one joint. Total ultrasonography sum score for osteophytes was high (mean 45 ±SD 12), whereas sum score was low for positive Doppler signal (mean 5.9 ±SD 4.4), with intermediate sum scores for synovial thickening and effusion (mean 16 ±SD 6.3 and 11 ±SD 6.0 respectively). Static sum scores were overall slightly higher (osteophytes mean 48 ±SD 10; Doppler mean 6.9 S±D 5.0; synovial thickening mean 20 ±SD 7.0 and effusion 13 ±SD 6.5)Agreement at baseline was good to excellent at joint level (kappa 0.72-0.88) and moderate to excellent at patient level (ICC 0.59-0.86). Agreement for delta sum scores was poor to fair for synovial thickening and effusion (ICC 0.18 and 0.34 respectively), but excellent for Doppler signal (ICC 0.80) (Table 1).Real-time ultrasonography showed responsiveness to prednisolone with a mean between-group difference of synovial thickening sum score of -2.5 (CI:-4.7 to-0.3). Static ultrasonography did not show a decrease in synovial thickening (Figure 1). No difference in ultrasonography scores was seen for the other ultrasonography features, neither with real-time nor static scoring.Conclusion:While cross-sectional agreement between real-time and static ultrasonography was good, agreement of delta sum scores was not and paired static ultrasonography measurement of synovial thickening did not show responsiveness to prednisone therapy where real-time ultrasonography did. Therefore, when using ultrasonography in clinical trials, real-time dynamic scoring should remain the standard.Table 1.Agreement on patient levelBaselineWeek 6Delta W6-BLICC (95% CI)ICC (95% CI)ICC (95% CI)Synovitis0.59 (0.26-0.76)0.58 (0.24-0.77)0.18 (0 - 0.40)Effusion0.84 (0.66-0.92)0.84 (0.75-0.89)0.34 (0.12-0.53)Osteophytes0.82 (0.50-0.92)0.78 (0.56-0.88)NDDoppler0.86 (0.75-0.92)0.91 (0.85-0.94)0.80 (0.70 -0.87)ICC: intra-class correlation coefficient linear mixed model (random patient, fixed rating), absolute agreement. ND: Not DerterminedDisclosure of Interests:Lotte van de Stadt: None declared, Féline Kroon: None declared, Monique Reijnierse Grant/research support from: Dutch Arthritis Foundation, Désirée van der Heijde Consultant of: bbVie, Amgen, Astellas, AstraZeneca, Bayer, BMS, Boehringer Ingelheim, Celgene, Cyxone, Daiichi, Eisai, Eli-Lilly, Galapagos, Gilead, Glaxo-Smith-Kline, Janssen, Merck, Novartis, Pfizer, Regeneron, Roche, Sanofi, Takeda, UCB Pharma, Frits Rosendaal: None declared, Naghmeh Riyazi: None declared, R. de Slegte: None declared, Jende van Zeben: None declared, Cornelia Allaart: None declared, Margreet Kloppenburg Consultant of: Abbvie, Pfizer, Levicept, GlaxoSmithKline, Merck-Serono, Kiniksa, Flexion, Galapagos, Jansen, CHDR, Grant/research support from: MI-APPROACH, Marion Kortekaas: None declared


2021 ◽  
Vol 77 (09) ◽  
pp. 6566-2021
Author(s):  
Ömer Şengül ◽  
İbrahim Ak ◽  
Berna Emsen

In this study, we investigated the effect of royal jelly on the puberty of female ¼ Romanov × ¾ Morkaraman crossbred lambs. Royal jelly was applied in two ways: orally and intravaginally. The rate of estrus as well as the day and time (in hours) of estrus were observed and determined by real-time ultrasonography (for pregnancy) and laparoscopic surgery (ovary examination). Three groups of lambs were observed. The first group, consisting of 15 female lambs, was treated intravaginally; in the second group, 15 female lambs were treated orally; and the third group, which served as control, consisted of 10 ewe lambs that were not treated with royal jelly. Estrus rates in the intravaginally and orally treated groups were 13% and 20%, respectively, whereas the control group showed no estrus activity. However, estrus interval in both groups was observed 3-5 days after the withdrawal of the treatment. All the animals had an active ovary when observed during estrus activity by ovary examination. Yearling ¼ Romanov-bred ewes respond positively to royal jelly application. Increasing the doses and extending the duration of royal jelly application might yield better results.


2020 ◽  
Vol 43 (8) ◽  
pp. 816-823
Author(s):  
Carlos De la Fuente ◽  
Rony Silvestre ◽  
Paula Baechler ◽  
Antonia Gemigniani ◽  
Karol Grunewaldt ◽  
...  

Author(s):  
Faiz Muhammad Khand ◽  
Allah Bux Kachiwal ◽  
Zubair Ahmed Laghari ◽  
Shakeel Ahmed Lakho ◽  
Pershotam Khattri ◽  
...  

2019 ◽  
Vol 12 (1) ◽  
pp. 6-12
Author(s):  
I Alawiy ◽  
T Mohammed ◽  
A Majeed

This study was achieved in a special farm in Basaer village which lies on the right side of the Euphrates in Heet district l Anbar, Heet lies 70 K.M west Ramadi during the pesiod, From 17/4/2018 to 30/5/2018. 28 ewes aged 2-4 years of awassi with average weight 40-50 k.g. and a one lambing. All ewes were diagnosed by using the real-time Ultrasonography to make sure there is no pregnancy among the female before the experiment. All ewes were synchronized with intravaginal sponges impregnated with 60 mg MAP for 12 days before sponges withdrawal and eCG 500 IU (Novormon made in Argentina). The pregnant ewes were divided randomly and equally (7 each group) Into 4 groups The ewes in the first group were received an intramuscular injection of 160 Mµ of arginine 3 times daily. The second group were treated with 2ml/head a combination of selenium plus vitamin E (vitamin E 68mg/ml Selenium 1.5mg/ml). The third group was treated by injection of 160 Mµ of arginine and selenium with vitamin E 2 ml/head. The four groups were injected with normal saline which was considered as a control group. The ewes were inseminated by ram at the end of the hormonal program for five days. The samples of blood were taken from the Jugular vein at four-day treatment Also, In the 4, 10, 15, 18. The results of the experiment showed no significant deferent in WBC, Progesterone estrogen, growth hormone, prolactin, early of pregnancy in the treatment with the control group. The experiment showed a significant difference in the Progesterone concentration within a single treatment in three treatment without control. concluded from this study that use of arginine and selenium with vitamin E improves ewes health, increasing the progesterone to maintain pregnancy.


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