histology report
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2021 ◽  
Author(s):  
ANDILE SICOLIWE THAKA

Abstract Hysterectomy is a procedure commonly performed to treat uterine and cervical disorders. It is a common procedure in developing countries, others listing it as the most common gynecological procedure in developed countries. The aim of the study is to determine the epidemiology profile of hysterectomy in Northern Zimbabwean women. It can either be classified according to the procedure used to perform the hysterectomy; which could be a total abdominal hysterectomy, uterus only, subtotal hysterectomy, total abdominal hysterectomy plus salphingo-oophorectomy, total abdominal hysterectomy plus bisalphingo-oophorectomy and radical hysterectomy. It can be vaginally, abdominally or laparoscopy assisted. Laparoscopy assisted vaginal hysterectomy is less common as the procedure is semi-automated. The aim of the study was to determine the prevalence of hysterectomy among the women in northern Zimbabwe, identifying patterns of occurrences and distribution of hysterectomy and determining possible indicators of hysterectomy. Parirenyatwa Group of Hospitals undertakes Histology laboratory testing of samples from hospitals in Northern Zimbabwe as the referral laboratory. A retrospective study was conducted using the census sampling method to determine the epidemiology profile of hysterectomy. The study collected 350 reports from 2019 that indicated to have been from hysterectomy and therefore the estimated prevalence rate of hysterectomy was 9.81%. The study looked at the reports of specimens brought in due to the performance of hysterectomy. The inclusion criteria of a report was a complete histology report from the Pathologist from specimens processed and microscopy slides prepared by the Scientist. Exclusion criteria was an incomplete report. Leiomyomata, post-partum hemorrhaging and chronic pelvic pain were the leading possible indicators of hysterectomy. The procedure was most commonly performed on women between the ages of 41-50 years. The total abdominal hysterectomy was 59.81% performed most of the time with most reports from Parirenyatwa Group of Hospitals and then Mutare Provincial Hospital. Delimitations was the low resource costing of the study and the automated collection of the data. The limitations were clerical errors, lack of patient data such as clinical history and lack of history or socio-economic demographics collected by the laboratory form. There is need for better data management and increase in the variation of data to collect such as clinical history, parity, marital status, income setting and other factors. Further studies can be done to give a holistic picture of the epidemiology profile of hysterectomy in Zimbabwe. There is need for an awareness campaign on hysterectomy as it is a growing common procedure among women in developing countries. Case studies would give intrinsic details unavailable in reports. Better Sexual and reproductive health information should be availed on indicators of hysterectomy according to their prevalence in different age groups.


2021 ◽  
Vol 5 ◽  
pp. 85-88
Author(s):  
Ubong Bassey Akpan ◽  
Theophilus Ipeh Ugbem ◽  
Ezukwa Omoronyia

Corpus luteum cyst is common in early pregnancy and seldom exceeds 5 cm in diameter; many of which resolve before the end of the first trimester of pregnancy. Giant corpus luteum cyst in third trimester is very rare especially in naturally-conceived pregnancies. We hereby report a rare case of twisted giant corpus luteum cyst in the third trimester in a 33-year-old multigravida. She presented with acute abdominal pain and vomiting at a gestational age of 34 weeks. Ultrasound scan revealed a twisted giant right ovarian cyst. She underwent an emergency cesarean delivery and right oophorectomy. Histology report showed features that were diagnostic of corpus luteum cyst.


2021 ◽  
Vol 14 (10) ◽  
pp. e245945
Author(s):  
Jiawei Alexander Yap ◽  
Manish M Bundele ◽  
Ming Yann Lim ◽  
Julian Park Nam Goh

Lymphoepithelial carcinoma (LEC) of the larynx is an extremely rare tumour which, unlike its nasopharyngeal counterpart, has shown a propensity to affect elderly Caucasian men and is not commonly associated with Epstein-Barr virus. We present a 70-year-old Chinese man who complained of hoarseness and dysphagia. Nasoendoscopy revealed a left supraglottic tumour. Preoperative MRI (in particular Diffusion Weighted Imaging) showed the possibility of two distinct components within a tumour. The patient underwent total pharyngolaryngectomy and bilateral selective neck dissection. The final histology report confirmed the presence of a tumour with two distinct components: predominant LEC with a smaller conventional (keratinising) squamous cell carcinoma component. The patient recovered well after surgery and subsequently underwent adjuvant radiotherapy. Final staging was pT3 N2c M0 (AJCC stage IVA). Follow-up over 2 years revealed no tumour recurrence.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Ali Toffaha ◽  
Samir Al Hyassat ◽  
Walid Elmoghazy ◽  
Hatem Khalaf ◽  
Ahmed Elaffandi

Schistosomiasis is one of the most prevalent parasitic infections in the developing world. When it affects the gastrointestinal system specifically the liver, it causes periportal fibrosis followed by cirrhosis. Cholecystitis however is a rare presentation, and associated liver abscess has certainly never been reported to date. We report a case of acute cholecystitis complicated by cholangitis and liver abscess in a 46-year-old man. After complex course of treatment, he had laparoscopic cholecystectomy, and the histology report confirmed schistosomiasis. Gallbladder schistosomiasis is an uncommon disease that is associated with dense fibrotic changes that strongly mimics xanthogranulomatous cholecystitis. Liver abscess may occur during the disease evolution especially in patient originating from endemic backgrounds. We present the case and a comprehensive literature review.


2021 ◽  
Vol 184 (5) ◽  
pp. 677-686
Author(s):  
A Rozenbaum ◽  
C Buffet ◽  
C Bigorgne ◽  
B Royer ◽  
A Rouxel ◽  
...  

Objective Active surveillance of cytologically proven microcarcinomas has been shown as a safe procedure. However, fine needle aspiration biopsy (FNAB) is not recommended by European Thyroid Association (ETA) and American Thyroid Association (ATA) guidelines for highly suspicious nodules ≤ 10 mm. The aim of the study was to assess the outcomes of active surveillance of EU-TIRADS 5 nodules ≤ 10 mm not initially submitted to FNAB. Patients and methods 80 patients with at least one EU-TIRADS 5 nodule ≤ 10 mm and no suspicious lymph nodes, accepting active surveillance, were included. Results Mean baseline diameter and volume were 5.4 mm (±2.0) and 64.4 mm3 (±33.5), respectively. After a median follow-up of 36.1 months, a volumetric increase ≥ 50% occurred in 28 patients (35.0%) and a suspicious lymph node in 3 patients (3.8%). Twenty-four patients underwent an FNAB (30.0%) after at least a 1 year follow-up of which 45.8% were malignant, 8.3% benign, 33.3% undetermined and 8.3% nondiagnostic. Sixteen patients (20.0%) underwent conversion surgery after a median follow-up of 57.2 months, confirming the diagnosis of papillary carcinoma in 15/16 cases (not described in 1 histology report), all in remission at 6–12 months postoperative follow-up. Conclusion Applying ETA and ATA guidelines to avoid FNA of EU-TIRADS 5 sub-centimeter nodules and proceeding to active surveillance of such nodules in selected patients is a safe procedure. Thus, US-FNAB could be postponed until the nodule shows signs of progression or a suspicious lymph node appears, with no added risk for the patient.


2020 ◽  
Vol 14 (1) ◽  
pp. 665-670
Author(s):  
Francesca Romana Grippaudo ◽  
Pasquale Fino ◽  
Vito Vincenzo Gomes ◽  
Cristina Grippaudo

Background: Although dermal filler injections are a widespread and secure practice, early or late complications may nonetheless occur. Objective: In this paper, the authors report an unusual asymptomatic late filler infection caused by Actinomycetes in a patient having received liquid silicone and acrylate filler injections for lip enhancement, seeking treatment for upper lip macrocheilia. Methods: The case report is about a patient who complained of recurrent lip region edema and denied any infective episodes. Preoperative analysis was in the normal range. Sonographic exam showed two fillers in the upper lip, suggestive of silicone and polyacrylamide gel. A conservative macrocheilia reduction was performed; healing was uneventful. Results: Histology report confirmed the preoperative sonographic diagnosis, together with an actinomycetes infection, clinically unsuspected. Many microorganisms have been reported to cause abscesses or granuloma after dermal filler treatments, sterile abscesses were reported as well, suggesting a biofilm infection as causative granuloma origin. Conclusion: This study differs from previous filler complication reports because of the occasional finding of a silent actinomyces infection, a commensal of the oral cavity but responsible for suppurative diseases in the soft tissues. This occasional finding seems to support the biofilm origin of dermal filler granuloma.


Cureus ◽  
2020 ◽  
Author(s):  
George S Stoyanov ◽  
Lilyana Petkova ◽  
Deyan L Dzhenkov ◽  
Nikolay R Sapundzhiev ◽  
Iliyan Todorov

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Rodgers N. Demba ◽  
Sylviah M. Aradi ◽  
Matilu Mwau ◽  
Walter O. Mwanda

Background: Histology is used to identify Kaposi’s sarcoma (KS) in countries with low resources to fund healthcare costs. Approximately 95% of KS cases can be detected using a polymerase chain reaction.Objective: To determine the presence of the open reading frame 75 (ORF75) gene associated with Kaposi’s sarcoma herpes virus among HIV-1/AIDS patients and to describe morphological presentations of KS.Methods: This was a retrospective, descriptive study of archived tissue blocks collected from 2013 to 2016. Haematoxylin and eosin staining was used to identify KS. Deoxyribonucleic acid from archived tissue blocks was extracted and a nested polymerase chain reaction was used to detect the ORF75 gene.Results: All 81 cases in this study had been diagnosed as HIV-1 positive, of which 68 had hallmark features of KS in the histology report and 13 had features suggestive of KS (‘KS-like’). Microscopic identification of KS by haematoxylin and eosin staining was considered a significant indicator of KS herpes virus ORF75 gene positivity (p = 0.002). The ORF75 gene was detected in 60.5% (49/81) of tissue blocks; 27.2% were men (22/81) and 33.3% were women (27/81). The ORF75 gene was observed to be present in up to 15.4% (2/13) of the cases reported to have KS-like features.Conclusion: Following the initial diagnosis of KS by histology, the ORF75 gene was fur-ther detected from both cases that had hallmark features of KS as well as among cases with KS-like fea-tures.


2020 ◽  
Vol 16 (5) ◽  
pp. 85-89
Author(s):  
Francesco Londero ◽  
Luigi Castriotta ◽  
William Grossi ◽  
Gianluca Masullo ◽  
Angelo Morelli ◽  
...  

Open thoracotomy during pulmonary metastasectomy allows lung palpation and may discover unexpected further nodules. We assess the validity of intraoperative lung ultrasonography via thoracoscopy in identifying lung nodules. A first surgeon will perform an ultrasonographic investigation on the deflated lung by thoracoscopy. A second surgeon will then perform a manual exploration of the organ by thoracotomy. Data on number and localization of nodules will be matched and compared with final histology report. Sensitivity and specificity will be assessed. Concordance will be assessed with Cohen K test. Calculated sample size is 89 patients. This study might have an important role in shifting the surgical practice towards a less invasive approach, with consequent benefits for the patient. Protocol is registered on clinicaltrials.gov . Protocol registration number: NCT03864874.


Author(s):  
T. A. Oyedele ◽  
B. Sodipo ◽  
O. A. Adetayo ◽  
A. O. Ajimoko ◽  
E. Olawale

Introduction: Avulsion has been described as the traumatic displacement of the tooth out of the socket, and it accounts for 0.5% to 16% of traumatic injuries in the permanent dentition. Many complications have been associated with avulsed tooth following replantation. This paper aimed at presenting a case of the large cystic lesion following replantation of avulsed teeth. Case Presentation: A case of a 17-year-old undergraduate student who presented in the dental clinic for medical screening as a mandatory exercise upon gaining admission. During the examination, a purulent pus discharge was noticed on the labial sulcus about tooth 11. History revealed that she had avulsion of teeth 11 and 12 about 4-years earlier that was replanted and splinted for 2-3 weeks and subsequently she was discharged from the clinic without any further treatment. Radiographic examination revealed periapical radiolucency without well define margin about teeth 11 and 12. Periapical surgery was carried out and two large cystic cavities were seen at about teeth 11 and 12 during surgery. The histology report of the specimen revealed a benign lesion suggesting periapical cyst. Conclusion: There is the need for adequate follow-up and monitoring of replanted teeth the following avulsion to arrest any complication that might arise from the procedure. Also, the importance of endodontic treatment following replantation of the avulsed tooth cannot be overemphasized.


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