brain density
Recently Published Documents


TOTAL DOCUMENTS

30
(FIVE YEARS 2)

H-INDEX

10
(FIVE YEARS 1)

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
M. A. Nettis ◽  
M. Veronese ◽  
N. Nikkheslat ◽  
N. Mariani ◽  
G. Lombardo ◽  
...  

2016 ◽  
Vol 219 (3) ◽  
pp. 299-299
Author(s):  
Erin McCallum
Keyword(s):  

2016 ◽  
Vol 18 ◽  
pp. 62-65 ◽  
Author(s):  
Miyu Sugimoto ◽  
Hideki Hyodoh ◽  
Masumi Rokukawa ◽  
Ayumi Kanazawa ◽  
Rina Murakami ◽  
...  
Keyword(s):  

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Jian Xu ◽  
Yuqi Cheng ◽  
Aiyun Lai ◽  
Zhaoping Lv ◽  
Robert A. A. Campbell ◽  
...  

This study explores the relationship between autoantibodies and brain density reduction in SLE patients without major neuropsychiatric manifestation (NPSLE). Ninety-five NPSLE patients without obvious cerebral deficits, as determined by conventional MRI, as well as 89 control subjects, underwent high-resolution structural MRI. Whole-brain density of grey matter (GMD) and white matter (WMD) were calculated for each individual, and correlations between the brain density, symptom severity, immunosuppressive agent (ISA), and autoantibody levels were assessed. The GMD and WMD of the SLE group decreased compared to controls. GMD was negatively associated with SLE activity. The WMD of patients who received ISA treatment were higher than that in the patients who did not. The WMD of patients with anticardiolipin (ACL) or anti-SSB/La antibodies was lower than in patients without these antibodies, while the GMD was lower in patients with anti-SM or anti-U1RNP antibodies. Thus, obvious brain atrophy can occur very early even before the development of significant symptoms and specific autoantibodies might contribute to the reduction of GMD or WMD in NPSLE patients. However, ISAs showed protective effects in minimizing GMD and WMD reduction. The presence of these specific autoantibodies might help identify early brain damage in NPSLE patients.


2014 ◽  
Vol 11 (1) ◽  
pp. 69-73 ◽  
Author(s):  
M Uddin ◽  
MHR Sarker ◽  
ME Hossain ◽  
MS Islam ◽  
MB Hossain ◽  
...  

This study was intended to investigate some aspects of the morphometric characteristics of the neurocranium in domestic cat (Felis catus) of Bangladesh. Twenty adult domestic cat including 10 males and 10 female were euthanized using diazepam (@ 20 mg/kg) and their skulls were macerated to give morphometric parameters. Student t-test with level of significance set at 5% (p < 0.05) was used to analyze the obtained values. The mean (mean ± SE) neurocranial volume was 28 ± 0.97 ml, neurocranial length was 6.63 ± 0.77 cm, and the neurocranial height and index were 3.32 ± 0.38 cm and 49.83%, respectively. The mean height and width of the foramen magnum were 1.32 ± 0.09 cm and 1.35 ± 0.08 cm, respectively, while the foramen index was below 100 at 90.72 ± 4.93. Parameters for the foramen magnum index showed significant difference between both sexes at p < 0.05. The foramen magnum showed shape variations and there were multiple hypoglossal foramina in over 80% of the cats. Foramen magnum index was positively correlated with neurocranial volume. The results were discussed in terms of the usage of morphologic and morphometric characteristics of cranium and skulls in several basic and clinical applications in cat such as estimation of the brain density and the use of the cat for cranial pressure experiments. DOI: http://dx.doi.org/10.3329/bjvm.v11i1.17302 Bangl. J. Vet. Med. (2013). 11 (1): 69-73


2010 ◽  
Vol 4 (4) ◽  
pp. 332-337 ◽  
Author(s):  
Renata Eloah de Lucena Ferretti ◽  
Wilson Jacob-Filho ◽  
Lea Tenenholz Grinberg ◽  
Renata Elaine Paraízo Leite ◽  
José Marcelo Farfel ◽  
...  

Abstract The present study aimed to establish the morphometric brain changes during aging in a necropsy series from Brazil and determine whether sexual dimorphisms interfere in these changes. Methods: A cross-sectional study was conducted at the São Paulo Autopsy Service in Brazil where, after informed consent, data was gathered from next of kin interview with reference to clinical status prior to death. Brain weight, volume and density measurements were taken and then adjusted for head circumference. Descriptive statistics and tests of hypothesis and correlations were applied, considering a p-value of 0.05. Results: 414 subjects, mostly men (60.4%), with a mean age of 67.1 years, were included. The mean brain weight of the sample was 1219.2g±140.9 and mean volume was 1217mL±152.3. The mean brain density of the sample was 1.0g/mL±0.09. Values differed between males and females in terms of weight and volume. Brain weight decreased during aging by about 45g per decade (r= -0.300; p<0.01) and volume by about 43mL (r= -0.278; p<0.00). Mean density of the sample was 1.0 g/mL in both genders. Conclusions: Brain weight and volume (with or without corrections) decreased during aging, and these reductions were more pronounced in women. Density remained unchanged for both genders. Further studies are needed to investigate factors associated to these reductions.


Brain ◽  
2010 ◽  
Vol 133 (10) ◽  
pp. 3080-3092 ◽  
Author(s):  
Astrid C. van der Schot ◽  
Ronald Vonk ◽  
Rachel M. Brouwer ◽  
G. Caroline M. van Baal ◽  
Rachel G. H. Brans ◽  
...  

2008 ◽  
Vol 130 (2) ◽  
Author(s):  
V. Kostopoulos ◽  
T. H. Loutas ◽  
C. Derdas ◽  
E. Douzinas

The present work deals with the application of an innovative in-house developed wavelet-based methodology for the analysis of the acceleration responses of a human head complex model as a simulated diffused oedema progresses. The human head complex has been modeled as a structure consisting of three confocal prolate spheroids, whereas the three defined regions by the system of spheroids, from the outside to the inside, represent the scull, the region of cerebrospinal fluid, and the brain tissue. A Dirac-like pulse has been used to excite the human head complex model and the acceleration response of the system has been calculated and analyzed via the wavelet-based methodology. For the purpose of the present analysis, a wave propagation commercial finite element code, LS-DYNA 3D, has been used. The progressive diffused oedema was modeled via consecutive increases in brain volume accompanied by a decrease in brain density. It was shown that even a small increase in brain volume (at the level of 0.5%) can be identified by the effect it has on the vibration characteristics of the human head complex. More precisely, it was found that for some of the wavelet decomposition levels, the energy content changes monotonically as the brain volume increases, thus providing a useful index of monitoring an oncoming brain oedema before any brain damage appears due to uncontrolled intracranial hypertension. For the purpose of the present work and for the levels of brain volume increase considered in the present analysis, no pressure increase was assumed into the cranial vault and, associatively, no brain compliance variation.


Sign in / Sign up

Export Citation Format

Share Document