Length-dependent motions of SARS-CoV-2 frameshifting RNA pseudoknot and alternative conformations suggest avenues for frameshifting suppression

Conserved SARS-CoV-2 RNA regions of critical biological functions define excellent targets for anti-viral therapeutics against Covid-19 variants. One such region is the frameshifting element (FSE), responsible for correct translation of viral polyproteins. Here, we analyze molecular-dynamics motions of three FSE conformations, discovered by graph-theory analysis, and associated mutants designed by graph-based inverse folding: two distinct 3-stem H-type pseudoknots and a 3-way junction. We find that the prevalent H-type pseudoknot in literature adopts ring-like conformations, which in combination with 5′ end threading could promote ribosomal pausing. An inherent shape switch from “L” to linear that may help trigger the frameshifting is suppressed in our designed mutant. The alternative conformation trajectories suggest a stable intermediate structure with mixed stem interactions of all three conformations, pointing to a possible transition pathway during ribosomal translation. These observations provide new insights into anti-viral strategies and frameshifting mechanisms.

THE IMPORTANCE OF MEANING IN ARABIC TEXTBOOK TRANSLATION

<pre><a name="_Hlk89781071"></a><span class="y2iqfc"><span lang="EN-US">The translation process includes transferring the source language into the target language with the intention of knowing the meaning. When meaning is expressed to the reader, then all information, insight, and knowledge can also be understood. As in textbooks, knowledge conveyed through texts in it of course have references from foreign languages, including Arabic. Therefore, in this article there are several objectives; (1) becoming one of the references for writers and translators in understanding the importance of the translation process to find out the meaning of writing textbooks, (2) helping students and students learn to understand science through printed books. In particular, the discussion in this article is focused on understanding, strategies and the urgency of meaning in Arabic translation which is applied to writing lesson texts. This article uses a qualitative descriptive method. The data obtained are sourced from observations, findings, and literature reviews from various sources. The results of the analysis of this article are in the form of emphasizing the importance of the translation process as language transfer and messages from the source text which includes the source language into the target text which includes the target language. The translation process must refer to the understanding of both languages, and involve the sensitivity and feelings of the translator. This translation strengthens the position of language and cultural differences that are no longer a barrier in the development of science. Thus, by using a good and correct translation process, the meaning of textbooks can be fully grasped</span></span></pre>

Sürja traditsioon Põhja-Venemaa ja Siberi käsitöönduses ja rahvakunstis

The article deals with the term “Zyryanskoe” in the traditional designations of the material objects and art technologies among the people who live in the boundary territories with Komi-Zyryan’s. The article considers the ethnographic material that was gathered under the research project “The nomadic ornament: ethnic identity in the ornamental tradition of Izhma and Nenets reindeer herders”. The article is based on the published and contemporary field data. The author supposes that widely spread “Zyryan designations” among the Northern Russian, Nenets and Ob-Ugric people is the result of the high level of development and uniqueness of some traditional technologies of Komi-Zyryan. Also, this article presents recent field data on the ornamental tradition in the technique of decorating fur products among those modern Izhma Komi and Nenets, who live together in reindeer-herding settlements of the Nenets and Yamal-Nenets Autonomous Okrugs. The article discusses the ideas of Komi and Nenets masters about what represents the ethnic and cultural specifics in the artistic decoration of fur products. Also, this article focuses on the question of the reasons for loss of ethnic identity in the modern arts and crafts of the Komi. Special attention is paid to how Komi ethnicity is visualized in modern folk art. Finally the possibility of a correct translation of the ethnocultural heritage in the works of modern masters of Komi Republic is discussed.

Meaningful Translation and Transliteration for Marathi Language

Meaningful translation and transliteration is NP problem in case of languages like Marathi language as there are so many word disambiguation and multiple use and meaning of single word in different context is available. That is why identifying correct informational need and translating text into meaningful information is a tedious and error prone task. Google translate works on machine neuron network and WorldNet is an online reference system works on psycholinguistic theory of human memory. Both approaches are promising tools for language translation. Complete translation of Marathi text to English or English to Marathi also having problem of more complicated meaningless or tedious translation. Proposed algorithm is taking into consideration meaningful translation or transliteration as per user’s informational need. This novel approach consider machine neuron network for meaningful formation of translated sentence and morphological structure for correct translation of word based on ontological analysis of word.

Inflection rules for Marathi to English in rule based machine translation

Machine translation is important application in natural language processing. Machine translation means translation from source language to target language to save the meaning of the sentence. A large amount of research is going on in the area of machine translation. However, research with machine translation remains highly localized to the particular source and target languages as they differ syntactically and morphologically. Appropriate inflections result correct translation. This paper elaborates the rules for inflecting the parts-of-speech and implements the inflection for Marathi to English translation. The inflection of nouns, pronouns, verbs, adjectives are carried out on the basis of semantics of the sentence. The results are discussed with examples.

Problems Students Face in Translating Discourse Markers from English into Kurdish

This paper investigates the problems are found in the translation of discourse markers from English into Kurdish. One of the main problems that discourse markers cause for translators is that discourse markers may have various possible translation choices. Moreover, a discourse marker has many functions, i.e. it may have more than one function. It can be thus used to show a variety of relations between several written discourse parts. Accordingly, a translator has to decide the function that a discourse marker has in a definite context to give the correct translation. In this paper Fraser's Model of discourse markers analysis (1999) has been chosen for investigating discourse markers. As for the data analysis, four students of the Department of Translation at the University of Duhok have been chosen to translate the same text from English into Kurdish to show the difficulties in choosing the correct discourse markers in these four different translations. The results showed that there are no equivalents in choosing the correct discourse markers when translating them into Kurdish.

On the Question of the Translation of Some Philosophical Terms in the Article of G. Oberhammer “The Forgotten Secret of Human Love”

The article deals with the problem of translation of some Sanskrit, English and German philosophical terms found in the article of Austrian indologist G. Ober­hammer “The Forgotten Secret of Human Love. An Attempt of an Approach”, which is devoted to the phenomenon of human love in India of the ancient and medieval period in such texts as Kāmasūtra of Vātsyāyana, Sātvatasaṃhitā, Nyāyabhāṣya of Pakṣilasvāmin, Śaraṇāgatigadya of Rāmānuja, etc. (translation of the article is attached below). At the beginning of the article, brief information on Oberhammer and the study of his creative heritage in Russia is provided. In particular, such Sanskrit terms as “śṛṅgāra” (erotic mood), “kāma” (sexual de­sire), the English term “rest”, the German “Rest” are considered. The author poses the following questions: is it possible to translate the word “kāma” as “love”, “śṛṅgāra” (erotische Stimmungen) – as erotic mood, whether to translate the Eng­lish “rest” as “peace”, or as “remainder”: and replies that, basing on contextual use, for “kāma” it is better to use the translation “desire” (“sexual desire”) or leave the Sanskrit term as it is, as Oberhammer does for the most part, “erotic mood”, to be more precise, means “erotic feeling”, not “mood” and the English “rest” clearly means “the remainder”, more specifically – the abandonment of oneself to God. The author concludes that for the correct translation of English terms in articles devoted to Indological problems, it is necessary to refer directly to Sanskrit terms, in the case of translated articles, we must also check the text against the original language, and for translation of Sanskrit terms we should use specialized dictionaries, referring to cases of contextual use of that terms.

Digital Transformation Journeys

Big Data and Digitization are among the most talked about concepts of the last years. Whereas Big Data has more and more concrete outcomes, Digitization is still seen as far away future. Nowadays, however, the question is not anymore how to prepare for the upcoming Digitization. The question companies and organizations have to ask themselves is how to adapt to and in today's Digitizing World. A correct translation of this strategy is equally important. It requires a dynamic silver lining, compatible with interactive work clusters and a hybrid organization. Typically, this results in a new way of working and an appropriate approach to power this way of working. The way of working needs to be adapted to the redefined borders between reactivity and proactivity, the need for real-time service and contextual adaptation. It needs to be designed for agility. To provide value, an organic compromise has to be found that answers the need for creative freedom, and the need for a solid structure where guidance, management, and development of human capabilities is possible in a structured way.

Cadres, scripts, registres — complexité de traduction des mots polysémiques

The article deals with issues related to the description of polysemic units for supervised automatic translation of texts from French to Polish based on the object-oriented method by W. Banyś (AOO). Applying to the description additional tools allowing for the disambiguation — frames, scripts and register analysis — the author focuses on presenting the complexity of the description of lexical units. It should be stressed that the decision to assign meanings of such words one or another equivalents in the target language is determined by the criterion of preference. Some of the meanings of the word are easy to describe in such a way that the program can make a correct translation into the target language with a high degree of probability. However, there are often such meanings whose description is much more complex. The closer the meanings of the disambiguated words in the original and target language and the more similar the communication situation in which they are used, the more difficult it is to clearly indicate the boundaries between the meanings. In such cases, there is a much greater range of preferential character of the translation, which we have to adopt The French noun conjunction (f), chosen for analysis, reflects this phenomenon very well.

Relaciones Públicas y asociacionismo académico en España: AIRP, la Asociación de Investigadores en Relaciones Públicas

Associationism, a habitual professional and academic practice in all fields, present in Spain various peculiarities in the case of Public Relations, suffering from a lack of recognition and identification as an independent discipline since its inception. In the professional field, this leads to the appearance of multiple associations that, with different names and many times obviating the words Public Relations, bring together professionals in the sector, but in the field of university research and teaching there is no such associative tradition. In order to fill this gap, AIRP, the Association of Researchers in Public Relations of Spain, was founded in 2004. 16 years after its creation, this article analyzes the meaning and usefulness of said association, both at the beginning and at present, and takes stock of the evolution of Public Relations in Spain throughout this decade and a half, in the professional field and, above all, the academic one. A methodology based on a semi-structured interview with three of the four AIRP founding professors and a content analysis of various documents, such as the census and the entity's web portal, is proposed for this. Among the results obtained, the academic impulse that the networking and associative work of the majority of Spanish researchers in the field has entailed for Public Relations, who before the existence of AIRP worked independently; a boost that translates into greater scientific recognition of the profession and a notable improvement in the indicators of scientific production associated with it, with the consequent greater presence of the discipline in the study plans and the promotion of specialized teachers. Therefore, the importance of associationism is also corroborated in the academic, non-professional sphere, especially in the case of disciplines, such as Public Relations in Spain, which needed an important work of dignity. A process to which the high level of Spanish PR researchers undoubtedly contributes, which has allowed many of them access to full professor and even professorial positions, something unthinkable a few years ago. In relation to the eternal debate on the correct translation into Spanish of the term Public Relations, the researchers are committed to maintaining the name Relaciones Públicas which, although in the professional field is elusive, in the academic field it remains, even in the name of the Degree study. Finally, in relation to the history and evolution of AIRP, the entity has notably increased the number of partners since its foundation, counting on a presence in the majority of universities that offer Advertising and Public Relations studies. This expansion, which will continue to be promoted, must be compatible, however, with its vocation as a specialized entity, absolutely focused on the study of Public Relations. The entity's most immediate challenge is the preparation of the White Paper on the Scope of Public Relations, a guide for the preparation of study plans on the subject.