The Journal of Toxicological Sciences
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2739
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Published By Japanese Society Of Toxicology

1880-3989, 0388-1350
Latest Documents Most Cited Documents Contributed Authors Related Sources Related Keywords

scholarly journals Development challenges for carcinogenicity risk assessments of topical drugs

2022 ◽  
Vol 47 (1) ◽  
pp. 1-11
Author(s):  
Brett D Hollingshead ◽  
Nasir Khan ◽  
Maik Schuler ◽  
Zaher Radi
Keyword(s):  
Risk Assessments ◽  
Topical Drugs

scholarly journals A novel perfusion culture system for screening mitochondrial toxicity in primary mouse hepatocytes

2022 ◽  
Vol 47 (1) ◽  
pp. 13-18
Author(s):  
Chika Yamamoto ◽  
Akinori Takemura ◽  
Sanae Ishii ◽  
Atsushi Doi ◽  
Isao Saito ◽  
...  
Keyword(s):  
Culture System ◽  
Perfusion Culture ◽  
Mitochondrial Toxicity ◽  
Primary Mouse Hepatocytes ◽  
Primary Mouse ◽  
Mouse Hepatocytes

scholarly journals Acyl-CoA:diacylglycerol acyltransferase 1 inhibition in the small intestine increases plasma transaminase activity via the activation of protein kinase C pathway

2022 ◽  
Vol 47 (1) ◽  
pp. 19-30
Author(s):  
Hideaki Yokoyama ◽  
Taku Masuyama ◽  
Yuki Tanaka ◽  
Iori Tsubakihara ◽  
Kazuma Kondo ◽  
...  
Keyword(s):  
Small Intestine ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Transaminase Activity ◽  
Kinase C

scholarly journals Spatio-temporal distribution of reactive sulfur species during methylmercury exposure in the rat brain

2022 ◽  
Vol 47 (1) ◽  
pp. 31-37
Author(s):  
Takamitsu Unoki ◽  
Masahiro Akiyama ◽  
Yasuhiro Shinkai ◽  
Yoshito Kumagai ◽  
Masatake Fujimura
Keyword(s):  
Rat Brain ◽  
Temporal Distribution ◽  
Sulfur Species ◽  
Methylmercury Exposure ◽  
Reactive Sulfur Species ◽  
Spatio Temporal

scholarly journals Bisphenol A stabilizes Nrf2 via Ca2+ influx by direct activation of the IP3 receptor

2021 ◽  
Vol 46 (1) ◽  
pp. 1-10
Author(s):  
Ami Oguro ◽  
Atsushi Sugitani ◽  
Yukino Kobayashi ◽  
Rika Sakuma ◽  
Susumu Imaoka
Keyword(s):  
Bisphenol A ◽  
Direct Activation

scholarly journals Human ES and iPS cells display less drug resistance than differentiated cells, and naïve-state induction further decreases drug resistance

2021 ◽  
Vol 46 (3) ◽  
pp. 131-142
Author(s):  
Yulia Panina ◽  
Junko Yamane ◽  
Kenta Kobayashi ◽  
Hideko Sone ◽  
Wataru Fujibuchi
Keyword(s):  
Drug Resistance ◽  
Ips Cells ◽  
Differentiated Cells

scholarly journals A 28-day repeated oral dose toxicity study of enniatin complex in mice

2021 ◽  
Vol 46 (4) ◽  
pp. 157-165
Author(s):  
Hiromu Okano ◽  
Toshiya Okamura ◽  
Yasunori Takahashi ◽  
Kazumi Takashima ◽  
Ryota Ojiro ◽  
...  
Keyword(s):  
Oral Dose ◽  
Toxicity Study

scholarly journals Activation of PTP1B/EGFR signaling and cytotoxicity during combined exposure to ambient electrophiles in A431 cells

2021 ◽  
Vol 46 (4) ◽  
pp. 177-185
Author(s):  
Yumi Abiko ◽  
Kohki Kurosawa ◽  
Hiroto Yamakawa ◽  
Yoshito Kumagai
Keyword(s):  
Combined Exposure ◽  
Egfr Signaling ◽  
A431 Cells

scholarly journals Chronic cardiotoxicity assessment of BMS-986094, a guanosine nucleotide analogue, using human iPS cell-derived cardiomyocytes

2021 ◽  
Vol 46 (8) ◽  
pp. 359-369
Author(s):  
Shota Yanagida ◽  
Ayano Satsuka ◽  
Sayo Hayashi ◽  
Atsushi Ono ◽  
Yasunari Kanda
Keyword(s):  
Ips Cell ◽  
Nucleotide Analogue
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