Determination of blood loss in bimaxillary surgery: does the formula and the time point affect results?

This chapter evaluates the work of two theorists who have discussed in detail the phenomenon of “projection.” Friedrich Neumann's concept of the rhythmic pair differs from this book's account of projection most obviously in its isolation of the pair as an autonomous “whole,” its separation of rhythm and meter, and its invocation of time point for the determination of an event's boundaries. Although Neumann describes the process through which a rhythmic pair might become unified as a “higher order” discrimination, he does not consider the process through which equality is produced and removes projection from meter in order to characterize an exclusively rhythmic order that in many respects resembles Hugo Reimann's dynamic, “organic” model. By contrast, Moritz Hauptmann is concerned with the process whereby determinate duration and equality are created and proposes a theory in which meter, quite apart from rhythm, is regarded as a dynamic, organic phenomenon arising from an innate human disposition for equal measure. The chapter then considers Hauptmann's analysis of the formation of duple meter.

Download Full-text

Accurate Quantification of Two Key Time Points Used in the Determination of Hydroxyl Polyaluminum Species by Ferron Timed Spectrophotometry

Journal of AOAC International ◽

10.5740/jaoacint.14-073 ◽

2015 ◽

Vol 98 (1) ◽

pp. 225-229

Author(s):

Jing Zhang ◽

Xiaojing Yong ◽

Dongyan Zhao ◽

Qiuyi Shi

Keyword(s):

Sulfonic Acid ◽

Time Curve ◽

Absorption Time ◽

Time Points ◽

Complete Reaction ◽

Reaction Extent ◽

Accurate Quantification ◽

Time Point

Abstract The content of mononuclear Al (Ala%) changed with its determination time (ta) under different dosages of Ferron (7-iodo-8-hydroxyquinoline-5-sulfonic acid, [Ferron]), and the change of Ala% with [Ferron] at different ta was systematically investigated for the firsttime. Thus, the most appropriate ta was found with the optimal [Ferron]. Also, the judgment of the platform (flat or level portion) of the complete reaction on the absorption-time curve determined in the hydroxyl polyaluminum solution by Ferron timed spectrophotometry (Ferron assay) was first digitized. The time point (tb) of complete reaction between the medium polyaluminum (Alb)and Ferron reagent depended on the reaction extent, and time could not be used only to judge. Thus, the tb was accurately determined and reduced to half of original, which improved the experiment efficiency significantly. The Ferron assay was completely optimized.

Download Full-text

Determination of operative blood loss.

Anaesthesia ◽

10.1111/j.1365-2044.1969.tb02840.x ◽

1969 ◽

Vol 24 (2) ◽

pp. 219-229 ◽

Cited By ~ 5

Author(s):

A. G. Bond

Keyword(s):

Blood Loss ◽

Operative Blood Loss

Download Full-text

STUDIES ON A PRACTICAL METHOD FOR THE DETERMINATION OF OPERATIVE BLOOD LOSS

Annals of Surgery ◽

10.1097/00000658-195501000-00006 ◽

1955 ◽

Vol 141 (1) ◽

pp. 53-61 ◽

Cited By ~ 7

Author(s):

ALBERT J. PAQUIN ◽

VICTOR F MARSHALL ◽

BERNARD NATHANSON

Keyword(s):

Blood Loss ◽

Practical Method ◽

Operative Blood Loss

Download Full-text

Switching Systems: Active Mode Recognition, Identification of the Switching Law

Journal of Control Science and Engineering ◽

10.1155/2007/50796 ◽

2007 ◽

Vol 2007 ◽

pp. 1-11 ◽

Cited By ~ 12

Author(s):

Elom Ayih Domlan ◽

José Ragot ◽

Didier Maquin

Keyword(s):

Parametric Identification ◽

Output Data ◽

Discrete State ◽

Active Mode ◽

Switching Law ◽

Mode Recognition ◽

System Input ◽

Diagnosis Method ◽

Time Point

The problem of the estimation of the discrete state of a switching system is studied. The knowledge of the switching law is essential for this kind of system as it simplifies their manipulation for control purposes. This paper investigates the use of a model-based diagnosis method for the determination of the active mode at each time point based on the system input/output data. The issue of the parametric identification of the switching law is also addressed.

Download Full-text

A suitable time point for quantifying the radiochemical purity of 225Ac-labeled radiopharmaceuticals

EJNMMI Radiopharmacy and Chemistry ◽

10.1186/s41181-021-00151-y ◽

2021 ◽

Vol 6 (1) ◽

Author(s):

James M. Kelly ◽

Alejandro Amor-Coarasa ◽

Elizabeth Sweeney ◽

Justin J. Wilson ◽

Patrick W. Causey ◽

...

Keyword(s):

Radiochemical Purity ◽

Gamma Spectroscopy ◽

Early Time ◽

Secular Equilibrium ◽

Data Set ◽

Testing Procedures ◽

Layer Chromatography ◽

High Resolution Gamma Spectroscopy ◽

Time Point

Abstract Background As 225Ac-labeled radiopharmaceuticals continue to show promise as targeted alpha therapeutics, there is a growing need to standardize quality control (QC) testing procedures. The determination of radiochemical purity (RCP) is an essential QC test. A significant obstacle to RCP testing is the disruption of the secular equilibrium between actinium-225 and its daughter radionuclides during labeling and QC testing. In order to accelerate translation of actinium-225 targeted alpha therapy, we aimed to determine the earliest time point at which the RCP of an 225Ac-labeled radiopharmaceutical can be accurately quantified. Results Six ligands were conjugated to macrocyclic metal chelators and labeled with actinium-225 under conditions designed to generate diverse incorporation yields. RCP was determined by radio thin layer chromatography (radioTLC) followed by exposure of the TLC plate on a phosphor screen either 0.5, 2, 3.5, 5, 6.5, or 26 h after the plate was developed. The dataset was used to create models for predicting the true RCP for any pre-equilibrium measurement taken at an early time point. The 585 TLC measurements span RCP values of 1.8–99.5%. The statistical model created from these data predicted an independent data set with high accuracy. Predictions made at 0.5 h are more uncertain than predictions made at later time points. This is primarily due to the decay of bismuth-213. A measurement of RCP > 90% at 2 h predicts a true RCP > 97% and guarantees that RCP will exceed 90% after secular equilibrium is reached. These findings were independently validated using NaI(Tl) scintillation counting and high resolution gamma spectroscopy on a smaller set of samples with 10% ≤ RCP ≤ 100%. Conclusions RCP of 225Ac-labeled radiopharmaceuticals can be quantified with acceptable accuracy at least 2 h after radioTLC using various methods of quantifying particle emissions. This time point best balances the need to accurately quantify RCP with the need to safely release the batch as quickly as possible.

Download Full-text

BLOOD VOLUME AND HEMODYNAMIC CHANGES IN PREGNANTS, PARTURIENTS AND PUERPERAE

V F Snegirev Archives of Obstetrics and Gynecology ◽

10.18821/2313-8726-2018-5-1-4-8 ◽

2018 ◽

Vol 5 (1) ◽

pp. 4-8

Author(s):

Aleksandr M. Ronenson ◽

E. M Shifman ◽

A. V Kulikov

Keyword(s):

Blood Loss ◽

Cardiovascular System ◽

Blood Volume ◽

Postpartum Period ◽

Structural Changes ◽

Volume Status ◽

Infusion Therapy ◽

Circulating Blood Volume ◽

Functional Changes

In the article, there are considered questions of physiological changes of the blood volume status during pregnancy, parturition and in the postpartum period, features of functional and structural changes of the cardiovascular system. The determination of the circulating blood volume is still a stumbling block for obstetrician-gynecologists and anesthesiologists-resuscitators. Our view of the normal blood volume status during pregnancy is important in light of the assessment of the blood loss in the development of massive obstetric hemorrhage. The doctor needs to know what changes in the cardiovascular system are physiological and which are pathological in case of blood loss, with taking into account the functional changes in the heart that occur during pregnancy, parturition and in the earliest postpartum period. A deeper understanding of this problem will help the doctor avoid aggressive infusion therapy, which can lead to complications.

Download Full-text

Evaluation of percutaneous endoscopic lumbar discectomy in treatment of obese adolescents with lumbar disc herniation：A retrospective study

10.21203/rs.3.rs-389600/v1 ◽

2021 ◽

Author(s):

Haijiang Yu ◽

Bin Zhu ◽

Xiaoguang Liu

Keyword(s):

Propensity Score ◽

Blood Loss ◽

Operative Time ◽

Lumbar Disc ◽

Lumbar Discectomy ◽

Obese Patients ◽

Intraoperative Blood Loss ◽

Endoscopic Lumbar Discectomy ◽

Time Point

Abstract Background: Obese patients are at risk of complications such as poor wound healing and increased infection rates after spinal surgery. Percutaneous endoscopic lumbar discectomy (PELD) has advantages over conventional open surgery in the treatment of obese adult patients with lumbar disc herniation (LDH) because it can decrease perioperative complications and enhance satisfaction degrees of patients. However, no clinical studies have evaluated the efficacy of PELD in obese adolescents with LDH. This study aimed to evaluate the efficacy of PELD in the treatment of obese ALDH.Methods: We retrospectively collected clinical data from 208 patients with single-segment ALDH who underwent PELD treatment in our hospital between January 2015 and December 2019. According to the body mass index classification standard of obesity for adolescents in our country, the patients were divided into obese and non-obese groups (control group). Based on the preoperative baseline data of the two groups, propensity score matching was performed to select patients from the two groups for the comparative study. Perioperative data included operative time, intraoperative blood loss and length of postoperative hospitalization. The visual analog scale (VAS), Oswestry disability index (ODI) and modified MacNab criteria were recorded as the main indicators of the surgical outcome, and the recurrence rate and incidence of complications were recorded as the minor indicators. Results: The obese and control groups included 45 patients each after 1:1 propensity score matching. Both groups showed improvements in VAS and ODI scores after surgery and at each follow-up time point (p < 0.05). However, there was no significant statistical difference in VAS and ODI scores between the two groups at each follow-up time point (p >0.05). In addition, the differences in operative time, intraoperative blood loss, length of postoperative hospitalization, incidence of complications, and recurrence rate were not statistically significant between the two groups (p >0.05). At the final follow-up, there was no significant difference in the excellent and good rate of MacNab classification between the two groups (p >0.05). Conclusion: PELD is a safe and effective minimally invasive technique for the treatment of obese patients with ALDH. The efficacy of PELD in obese and non-obese patients with ALDH was comparable.

Download Full-text

Gender-specific differences in haemostatic parameters and their influence on blood loss in bimaxillary surgery

Clinical Oral Investigations ◽

10.1007/s00784-021-04347-z ◽

2022 ◽

Author(s):

Michael Schwaiger ◽

Sarah-Jayne Edmondson ◽

Jasmin Rabensteiner ◽

Florian Prüller ◽

Thomas Gary ◽

...

Keyword(s):

Blood Loss ◽

Statistical Significance ◽

Dentofacial Deformities ◽

Perioperative Bleeding ◽

Risk Patients ◽

Anticoagulant System ◽

Gender Specific Differences ◽

Bimaxillary Surgery ◽

Gender Specific ◽

Blood Loss Volume

Abstract Objective The objectives of this prospective cohort study were to establish gender-related differences in blood loss and haemostatic profiles associated with bimaxillary surgery. In addition, we aimed to identify if any gender differences could be established which might help predict blood loss volume. Materials and methods Fifty-four patients (22 males; 32 females) undergoing bimaxillary surgery for skeletal dentofacial deformities were eligible for inclusion. Blood samples were taken 1 day preoperatively and 48 h postoperatively for detailed gender-specific coagulation analysis incorporating global coagulation assays (endogenous thrombin potential) and specific coagulation parameters. Blood loss was measured at two different time points: (1) the end of surgery, visible intraoperative blood loss (IOB) using ‘subtraction method’; and (2) 48 h postoperatively perioperative bleeding volume (CBL-48 h) using ‘haemoglobin-balance method’ and Nadler’s formula. Correlation and regression analyses were performed to identify relevant parameters affecting the amount of blood loss. Results Significant differences in IOB and CBL-48 h were observed (p < 0.001). Men had higher IOB versus women, lacking statistical significance (p = 0.056). In contrast, men had significantly higher CLB-48 h (p = 0.019). Reduced CBL-48 h was shown to be most closely associated with the level of Antithrombin-III being decreased in females. Conclusions Male gender is associated with higher IOB and CBL-48 compared with females. Gender does not affect IOB regarding haemostatic profile but does correlate strongly with procedure length. Conversely, CBL-48 is closely associated with gender-specific imbalances in the anticoagulant system. Clinical relevance Knowledge of gender-related differences will help clinicians establish predictive factors regarding excessive blood loss in orthognathic surgery and identify at-risk patients.

Download Full-text