Abstract P097: Association Of Non-appetitive Eating With Hypertension In Women: Mediation By Body Mass Index

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Anna K Poon ◽  
Alison Field ◽  
Karen Mitchell ◽  
Ashley Gearhardt ◽  
Benita Jackson ◽  
...  

Introduction: Although non-appetitive eating phenotypes are associated with body mass index, the extent to which they are associated with hypertension is unknown. Hypothesis: We hypothesize that non-appetitive eating phenotypes are associated with hypertension. Methods: We examined participants in a substudy on disordered eating conducted in 2013-2015, nested within the prospective cohort, Nurses’ Health Study 2. Non-appetitive eating was defined by: 1) binge eating with loss of control; 2) disinhibited eating; 3) coping-motivated eating; and 4) food addiction. Prevalent hypertension was defined by self-reported clinician diagnosis. Odds ratios and 95% confidence intervals (OR, 95% CI) were used to estimate the association of non-appetitive eating with prevalent hypertension, adjusted for age and race. The difference method was used to estimate the proportion of the associations mediated by body mass index. Results: After excluding missing exposure (n=421), the analytic sample included n=4,687 women (of n=5,108 women). Average age was 60 years (range: 49 to 68); 18% (n=824) reported binge eating with loss of control; average disinhibited eating score was 3 (range: 0 to 7); average coping-motivated eating score was 2 (range: 1 to 5); and 7% (n=349) reported food addiction. Non-appetitive eating was associated with higher odds of hypertension. Binge eating with loss of control was associated with 60% higher odds (95% CI: 1.37, 1.87) of hypertension. Per unit, disinhibited eating was associated with 18% (95% CI: 1.14, 1.21) and coping-motivated eating was associated with 38% (95% CI: 1.29, 1.47) higher odds of hypertension. Food addiction (yes versus no) was associated with a 108% higher odds (95% CI: 1.67, 2.60) of hypertension. Body mass index mediated more than 85% of the associations of each non-appetitive eating phenotype with hypertension. Conclusions: Non-appetitive eating is associated with hypertension. Body mass index explained almost all of the associations between non-appetitive eating and hypertension. Prospective studies are needed to confirm the direction of the associations.

BMJ ◽  
2019 ◽  
pp. l4067 ◽  
Author(s):  
Maria Brandkvist ◽  
Johan Håkon Bjørngaard ◽  
Rønnaug Astri Ødegård ◽  
Bjørn Olav Åsvold ◽  
Erik R Sund ◽  
...  

AbstractObjectivesTo study the trajectories of body mass index (BMI) in Norway over five decades and to assess the differential influence of the obesogenic environment on BMI according to genetic predisposition.DesignLongitudinal study.SettingGeneral population of Nord-Trøndelag County, Norway.Participants118 959 people aged 13-80 years who participated in a longitudinal population based health study (Nord-Trøndelag Health Study, HUNT), of whom 67 305 were included in analyses of association between genetic predisposition and BMI.Main outcome measureBMI.ResultsObesity increased in Norway starting between the mid-1980s and mid-1990s and, compared with older birth cohorts, those born after 1970 had a substantially higher BMI already in young adulthood. BMI differed substantially between the highest and lowest fifths of genetic susceptibility for all ages at each decade, and the difference increased gradually from the 1960s to the 2000s. For 35 year old men, the most genetically predisposed had 1.20 kg/m2 (95% confidence interval 1.03 to 1.37 kg/m2) higher BMI than those who were least genetically predisposed in the 1960s compared with 2.09 kg/m2 (1.90 to 2.27 kg/m2) in the 2000s. For women of the same age, the corresponding differences in BMI were 1.77 kg/m2 (1.56 to 1.97 kg/m2) and 2.58 kg/m2 (2.36 to 2.80 kg/m2).ConclusionsThis study provides evidence that genetically predisposed people are at greater risk for higher BMI and that genetic predisposition interacts with the obesogenic environment resulting in higher BMI, as observed between the mid-1980s and mid-2000s. Regardless, BMI has increased for both genetically predisposed and non-predisposed people, implying that the environment remains the main contributor.


2019 ◽  
Vol 22 (4) ◽  
pp. 220-228 ◽  
Author(s):  
Bram J. Berntzen ◽  
Sakari Jukarainen ◽  
Leonie H. Bogl ◽  
Aila Rissanen ◽  
Jaakko Kaprio ◽  
...  

AbstractWe aimed to study the eating behavioral traits that associate with body mass index (BMI) among BMI-discordant twin pairs. This cross-sectional study examined self-reported eating behaviors in 134 healthy young adult twin pairs (57 monozygotic [MZ] and 77 same-sex dizygotic [DZ]), of whom 29 MZ and 46 DZ pairs were BMI discordant (BMI difference ≥ 3 kg/m2). In both MZ and DZ BMI-discordant pairs, the heavier co-twins reported being less capable of regulating their food intake optimally than their leaner co-twins, mainly due to ‘frequent overeating’. Furthermore, the heavier co-twins reported augmented ‘disinhibited eating’, ‘binge-eating scores’ and ‘body dissatisfaction’. The twins agreed more frequently that the heavier co-twins (rather than the leaner co-twins) ate more food in general, and more fatty food, in particular. No significant behavioral differences emerged in BMI-concordant twin pairs. Overeating — measured by ‘frequent overeating’, ‘disinhibited eating’ and ‘binge-eating score’ — was the main behavioral trait associated with higher BMI, independent of genotype and shared environment.


2020 ◽  
pp. 1-17
Author(s):  
Ilana Eshriqui ◽  
Angélica Marques Martins Valente ◽  
Luciana Dias Folchetti ◽  
Bianca de Almeida-Pititto ◽  
Sandra Roberta G. Ferreira

Abstract Objective: To investigate the association between maternal pre-pregnancy body mass index (BMI) and offspring body composition in adulthood. Design: Retrospective cohort. Undergraduates of nutrition or nutritionists were recruited at the baseline of the Nutritionists’ Health Study between 2014 and 2017. Maternal pre-pregnancy BMI and current life aspects were self-reported through online questionnaires. Three body compartments were DXA-determined. The following variables were obtained: body-fat (%), fat mass index (FMI) (kg/m2), android-to-gynoid fat ratio, visceral adipose tissue (VAT) (cm3), appendicular skeletal muscle mass index (ASMI) (kg/m2), total bone and femur mineral content (g) and density (g/cm2). Linear regression adjusted according to directed acyclic graphs recommendation was performed. Setting: São Paulo, Brazil. Participants: Healthy non-pregnant women (aged 20-45 years) (n=150). Results: Median age and BMI were 22 years (IQR=20; 29) and 22.3 kg/m2 (IQR=20.4; 25.3). Pre-pregnancy BMI≥25 kg/m2 was reported by 14.7% of mothers. In fully adjusted models, maternal pre-pregnancy BMI was associated with their daughters’ body-fat % (β=0.31; 95%CI=0.0004; 0.63), FMI (β=0.17; 95%CI=0.03; 0.30, android-to-gynoid ratio (β=0.01; 95%CI=0.004; 0.02) and VAT (β=0.09; 95%CI=0.02; 0.16), but not with total bone density (β=0.001; 95%CI=-0.003; 0.006) and content (β=7.13; 95%CI=-4.19; 18.46). Direct association with ASMI was also detected, but lost statistical significance when participants whose mothers were underweight were excluded. Conclusions: Maternal pre-pregnancy body mass index was directly associated with offspring general and visceral adiposity but seem not to be associated with bone mass. Results reinforce importance of avoiding excess of maternal adiposity, as an attempt to break the vicious cycle of obesity transmission.


2013 ◽  
Vol 74 (2) ◽  
pp. 135-141 ◽  
Author(s):  
Mythily Subramaniam ◽  
Louisa Picco ◽  
Vincent He ◽  
Janhavi Ajit Vaingankar ◽  
Edimansyah Abdin ◽  
...  

2007 ◽  
Vol 16 (1) ◽  
pp. 66-76 ◽  
Author(s):  
BJØRN BJORVATN ◽  
INA MARIE SAGEN ◽  
NICOLAS ØYANE ◽  
SIRI WAAGE ◽  
ARNE FETVEIT ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3893
Author(s):  
Monika M. Stojek ◽  
Paulina Wardawy ◽  
Charles F. Gillespie ◽  
Jennifer S. Stevens ◽  
Abigail Powers ◽  
...  

Background: Higher subjective social status (SSS) or a person’s perception of their social standing is related to better health outcomes, but few studies examined SSS in relation to obesity. Emotional eating and food addiction have been linked to obesity. Some studies indicated that manipulating SSS may lead to altered food intake, but the relationship between SSS and dysregulated eating, such as emotional eating and food addiction (FA), has not been examined. The goal of this study was to examine the associations between SSS in the community and the larger society, dysregulated eating (emotional eating and FA), and body mass index (BMI) in a majority racial minority sample. Methods: The participants (N = 89; 93% Black, 86% women, and 56% with obesity; 72% income lower than USD 2000), recruited from a publicly funded hospital in Atlanta, GA, completed the MacArthur Scale, Dutch Eating Behaviors Questionnaire, Yale Food Addiction Scale, Beck Depression Inventory, PTSD Symptom Checklist, and demographics questionnaire. Results: Twenty-two percent of the sample met the criteria for FA; those with FA had significantly higher BMI than those without (p = 0.018). In the hierarchical linear regression, the SSS community (but not in society) predicted higher severity of emotional eating (β = 0.26, p = 0.029) and FA (β = 0.30, p = 0.029), and higher BMI (β = 0.28, p = 0.046), independent from depression and PTSD symptoms. Conclusions: The findings indicate that, among Black individuals with predominantly low income in the U.S., perceived role in their community is associated with eating patterns and body mass. Given the small sample size, the results should be interpreted with caution.


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