CYTOLOGICAL DIAGNOSTICS OF INTRAOPERATIVE PERITONEAL WASHES IN GASTRIC CANCER

Diagnosis of peritoneal microcanceromatosis is the most important task allowing to determine treatment strategy for patients with stomach cancer. Laparoscopy combined with peritoneal flushing and subsequent cytological examination should be performed to detect the peritoneal microcanceromatosis at the preoperative stage. The objective of this work was to improve cytological diagnostics of peritoneal washings using immunocytochemical techniques and the cell block method. The work was carried out on the basis of 276 surgical peritoneal washings in patients with stomach cancer who were on treatment in the department of high-tech surgery of the Moscow Clinical Scientific Centre of the State Budgetary Healthcare Institution named after Loginov A.S. from June 2016 to June 2018. As a result, the optimal panel of monoclonal antibodies (Ber-EP4, CEA, CK20) was chosen, which increased the sensitivity from 52% to 96% and the specificity of cytological diagnosis from 80% to 98%, and the overall accuracy of the method from 67% to 98%.

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CYTOLOGICAL DIAGNOSIS AS A METHOD OF SCREENING OF PRE-MALIGNANT MELANOCYTIC TUMORS AND EARLY FORMS OF SKIN MELANOMA

Problems in oncology ◽

10.37469/0507-3758-2018-64-3-384-387 ◽

2018 ◽

Vol 64 (3) ◽

pp. 384-387

Author(s):

Viktor Novik ◽

D. Dreval

Keyword(s):

Laser Therapy ◽

Histological Examination ◽

Clinical Data ◽

Surgical Excision ◽

Cytological Diagnosis ◽

Skin Melanoma ◽

Cytological Examination ◽

Melanocytic Tumors ◽

Quality Character ◽

Atypical Nevi

Cytohistological comparisons to the account of the clinical data and revision of cytological and histological preparations on a material received from 21 patients are made. Cytomorphological features of juvenile nevi (Spitz-nevus, Reed-nevus), dysplastic and atypical nevi and early forms of melanoma are described. The establishment at cytological examination of good-quality character of melanocytic defeats at the account of the clinical data could be the basis for appointment laser therapy. At revealing of atypical melanocytes in cytological preparations patients should be referred to specialized oncological institutions for surgical excision of tumor with the subsequent histological examination. Thus cytological examination could be used in dermatological practice as a method of screening pre-malignant melanocytic tumors and skin melanoma.

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Possibilities of cytological diagnostics in gynecology. Human papillomavirus as an interdisciplinary problem

Terapevt (General Physician) ◽

10.33920/med-12-2201-02 ◽

2022 ◽

pp. 15-21

Author(s):

Oksana Anatolievna Gizinger ◽

◽

Irina Yurievna Lepina ◽

Marina Nikolaevna Bagdasaryan ◽

◽

...

Keyword(s):

Human Papillomavirus ◽

Screening Test ◽

Molecular Genetic ◽

Laboratory Diagnosis ◽

Diagnostic Methods ◽

Laboratory Diagnostics ◽

Cytological Examination ◽

Stage Of Development ◽

Current Stage ◽

Cytological Diagnostics

The article presents an analysis of current information on the etiology, pathogenesis, laboratory diagnosis of human papillomavirus. It is shown that at the current stage of development of laboratory diagnostics there is a reliable screening test — cytological examination of smears taken from the ecto- and endocervix. To diagnose HPV, a combination of microscopic (cytological studies) and molecular genetic (PCR) diagnostic methods is used.

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New Cell Block Method to Enhance the Cellular Yield in Mucous and/or Bloody Samples

Acta Cytologica ◽

10.1159/000501817 ◽

2019 ◽

Vol 64 (3) ◽

pp. 265-269 ◽

Cited By ~ 2

Author(s):

Heli Hakso-Mäkinen ◽

Ivana Kholová

Keyword(s):

Diagnostic Accuracy ◽

Study Design ◽

Diagnostic Utility ◽

Cytological Diagnosis ◽

Cell Block ◽

Block Method

Objective: Cell blocks (CBs) are used to complement cytological diagnosis and for ancillary testing. Dissatisfaction with the cellular yield of the CB is widely recognized. Various techniques have been developed to increase the diagnostic utility of CBs. Study Design: We invented a new CB technique to increase cellular yield and diagnostic accuracy suitable especially for mucous and/or bloody cytological samples. Results: The new CB technique is described in detail with illustrations and cases, where it increased the cellular yield and diagnostic accuracy. CBs prepared by this method are suitable also for ancillary techniques, namely immunocytochemistry. Conclusions: The newly described method showed a better cellular yield in mucous and/or bloody cytological specimens.

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Cytological diagnosis of infectious conjunctivitis in cats

E3S Web of Conferences ◽

10.1051/e3sconf/201913501073 ◽

2019 ◽

Vol 135 ◽

pp. 01073

Author(s):

Sergey Kartashov ◽

Anastasia Rakitjanskaya ◽

Marina Petrova ◽

Maria Sultanova ◽

Maria Oboeva

Keyword(s):

Rapid Diagnosis ◽

Cytological Diagnosis ◽

Cotton Swab ◽

Cytological Examination ◽

Feasible Method ◽

Non Invasive ◽

Sterile Cotton Swab

Cytological examination of conjunctival smears obtained from cats with conjunctivitis can reveal the severity and type of inflammation and diagnose conjunctivitis caused by Chlamydophila felis. The diagnosis of chlamydia was made by the study of material taken from the conjunctival sac with a sterile cotton swab by PCR. Material for cytological examination was taken from these cats. Cytological examination of inclusions interpreted as chlamydial, was detected in all cytologic smears from sick cats, and has not been detected in none of healthy cats. Thus, cytological examination is a convenient, non-invasive, easily feasible method, which is suitable for rapid diagnosis of chlamydial conjunctivitis in cats.

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Can Routine Laparoscopy Help to Reduce the Rate of Explorative Laparotomies for Gastric Cancer? Laparoscopy in Gastric Cancer

Diagnostic and Therapeutic Endoscopy ◽

10.1155/dte.6.125 ◽

2000 ◽

Vol 6 (3) ◽

pp. 125-131 ◽

Cited By ~ 7

Author(s):

Gian Carlo Roviaro ◽

Federico Varoli ◽

Davide Sonnino ◽

Ombretta Nucca ◽

Gianni Rabughino ◽

...

Keyword(s):

Gastric Cancer ◽

Stomach Cancer ◽

Sensitivity And Specificity ◽

Preoperative Staging ◽

Malignant Neoplasm ◽

Surgical Protocol ◽

Cancer Laparoscopy

1. Background We developed this surgical protocol about performing intraoperative laparoscopy for staging in every patient affected by stomach cancer. Sensitivity and specificity of intraoperative laparoscopy are compared with conventional preoperative staging techniques.2. Methods From January 1994 to June 1999, 83 patients affected by stomach cancer were accepted in our department: 12 patients (14.5%) were excluded from our study after the preoperative staging; in 71 patients (85.5%) an explorative laparoscopy as the first step of the operation was performed.3. Results Laparoscopy confirmed preoperative staging in 53 cases (74.6%), in 12 patients demonstrated an overstaging. Laparoscopy demonstrated in 6 patients unsuspected causes of unresectability.4. Conclusions When performed in patients affected by malignant neoplasm and declared resectable, intraoperative laparoscopy can demonstrate conditions not detectable by traditional preoperative investigations, consequently reducing to zero explorative laparotomies.

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A STUDY OF BODY CAVITY EFFUSIONS AND ITS DIAGNOSTIC UTILITY OF CELL BLOCK AS AN ADJUNCT TO CONVENTIONAL CYTOLOGICAL SMEARS

10.36106/ijsr/7529013 ◽

2020 ◽

pp. 10-11

Author(s):

Ankan Nandi ◽

Debarshi Jana

Keyword(s):

Observational Study ◽

Body Cavity ◽

Diagnostic Utility ◽

Cytological Diagnosis ◽

Cell Block ◽

Tissue Architecture ◽

Block Method ◽

Exclusion Criteria ◽

Cross Sectional ◽

Malignant Effusions

Background: The cell block technique is one of the oldest method for evaluation of body cavity fluids and it increases the sensitivity of the diagnosis in comparison to conventional smear study. The main advantage of cell block technique is preservation of tissue architecture and obtaining multiple sections for special stains. Aim: To assess the utility of cell block method in increasing the sensitivity of cytological diagnosis of body cavity effusions as an adjunct to conventional smear method. Material and methods: It was institution based cross sectional observational study. All patients presenting with effusion and those who was give consent for participating in the study was included in this study. The study was conducted in Dept. Of Pathology, Nandigram Superspeciality Hospital. 100 cases fulfilling the predetermined inclusion and exclusion criteria was taken during the study period. Result: Association of Cellularity vs cell block was statistically significant (p<0.0001). Association of Architectural Pattern vs cell block was not statistically significant (p=0.7883). Association of cytological smears vs cell block was statistically significant (p=<0.0001). Conclusion: Cell block technique is superior to conventional smear technique, especially for malignant effusions.

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Cytological diagnosis of microfilaria at unusual sites in clinically unsuspected cases: some rare presentations of filariasis

Tropical Doctor ◽

10.1177/0049475518793630 ◽

2018 ◽

Vol 48 (4) ◽

pp. 373-375 ◽

Cited By ~ 1

Author(s):

Shreekant Bharti ◽

Neeraj Kumar Agarwal ◽

Richa Katiyar ◽

Saloni Dwivedi ◽

Mridu Shri

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Body Fluids ◽

Cytological Diagnosis ◽

Cytological Examination ◽

Aspiration Cytology ◽

Fine Needle ◽

Needle Aspiration Cytology ◽

Rule Out

Filariasis is a major concern, particularly in endemic regions. The majority of patients harbouring the parasite may remain asymptomatic for years. Here, we present six patients who were sent for routine cytological examination to rule out neoplastic pathology, in whom cytology identified filarial infestation. The main purposes of our paper are to highlight the importance of fine needle aspiration cytology (FNAC), a cheap and quick investigation to detect the microfilaria from tissue swelling and body fluids, and to point out that clinicians practising in endemic regions should always consider filarial infestation in patients presenting with longstanding swelling.

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Operational cytological diagnostics in oncosurgery

Kazan medical journal ◽

10.17816/kazmj59670 ◽

1982 ◽

Vol 63 (1) ◽

pp. 7-9

Author(s):

M. Z. Sigal ◽

G. N. Khairutdinova

Keyword(s):

Operational Research ◽

Surgical Intervention ◽

Cytological Diagnosis ◽

Indications For Surgery ◽

Histological Findings ◽

Surgical Interventions ◽

Operating Field ◽

Puncture Biopsy ◽

Cytological Diagnostics

Abstract. The informative value of urgent cytological operational research in various areas of oncosurgery has been studied. The data of these studies were summarized during 773 operations, including 424 laparotomies, 195 thoracotomies and 154 other surgical interventions. Histological control confirmed the reliability of cytological findings in 93.9%. In 11 cases of discrepancy between cytological and histological findings, the reliability of the cytological diagnosis was subsequently established. It is recommended to include data from puncture biopsy of various objects of the operating field as criteria for resolving questions about indications for surgery, the volume and plan of surgical intervention.

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