scholarly journals Amelioration of Sarcoptic Mange-Induced Oxidative Stress and Growth Performance in Ivermectin-Treated Growing Rabbits Using Turmeric Extract Supplementation

Animals ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2984
Author(s):  
Salma H. Abu Hafsa ◽  
Haytham Senbill ◽  
Mohamed M. Basyony ◽  
Ayman A. Hassan
Keyword(s):  
Body Weight ◽  
Body Weight Gain ◽  
Antioxidant Properties ◽  
Nutrient Digestibility ◽  
Sarcoptic Mange ◽  
Control Treatment ◽  
Control Group ◽  
Thiobarbituric Acid Reactive Substance ◽  
Turmeric Extract ◽  
G Ratio

In this experiment, the protective effect of turmeric extract (TE) on side effects of Ivermectin-treated rabbits, while improving their performance, blood characteristics, and antioxidant status, was investigated. Sixty-three clinically Sarcoptes-infested rabbits aged 60 days were randomly allocated into three groups, with 21 rabbits in each group, to receive either no TE or TE supplementation (1 or 2 mg/kg diet) for 30 days after being subcutaneously injected with Ivermectin (IVM) 1% w/v at a dose of 0.2 mg/kg body weight twice a week. Another 21 healthy rabbits were used as the control. Treatment with IVM + 1 and 2 mg TE improved body weight (BW), body weight gain (BWG), feed intake (FI), and feed conversion ratio (FCR) in infested rabbits (p < 0.05). The IVM alone treatment had the highest mortality rate compared with the other treatments. Rabbits treated with IVM + 1 and 2 mg TE demonstrated progressive recovery manifested by improved nutrient digestibility and nitrogen balance. On day 7, the serum total protein, albumin, and albumin/globulin (A/G) ratio were significantly lower in the treated groups compared with the control group; also, the lowest values were observed in rabbits treated only with Ivermectin, followed by IVM + 1 and 2 mg TE. Treated rabbits had higher thiobarbituric acid reactive substance (TBAR) levels, but lower total antioxidant capacity (TAC), superoxidase dismutase (SOD), and glutathion peroxidase (GSH-Px) levels compared with the control group. On day 30 post-treatment, the rabbits in the IVM + 1 and 2 mg TE treatment groups showed progressive recovery manifested by improved biochemichal parameters, as well as a remarkable improvements in the oxidant/antioxidant balance towards normalcy (p < 0.05), and became comparable to that of the control compared with IVM alone treatment. In conclusion, turmeric extract improved rabbits’ performance toward normalcy, and has remarkable antioxidant properties and can be used in conjunction with a miticide to treat sarcoptic mange in rabbits.

scholarly journals The Effect of Feeding Native Faba Bean Seeds (Vicia faba L.) to Sows and Supplemented With Enzymes to Piglets and Growing Pigs

2018 ◽  
Vol 18 (4) ◽  
pp. 1007-1027 ◽  
Author(s):  
Małgorzata Świątkiewicz ◽  
Jerzy Księżak ◽  
Ewa Hanczakowska
Keyword(s):  
Body Weight ◽  
Soybean Meal ◽  
Faba Bean ◽  
Unsaturated Fatty Acids ◽  
Body Weight Gain ◽  
Nutrient Digestibility ◽  
Growing Pigs ◽  
Control Group ◽  
Feed Mixture ◽  
Almost All

AbstractThe aim of this experiment was to examine the possibility of replacing part of soybean meal in the diets of sows, their piglets and fatteners with two varieties of high- or low-tannin faba bean seed. Twenty-four sows were allocated to 3 groups, 8 animals in each. Control group (C) received standard feed mixture containing soybean meal as the main protein source. Next groups received standard feed mixture in which part of soybean meal was replaced by high-tannin variety Bobas (group HT) or low-tannin variety Kasztelan (group LT). Faba bean was added to diets at the level of 12 and 14% for pregnant and lactating sows, 6% for piglets, and 12 and 16% for fatteners (grower and finisher, respectively). Diets for half piglets and fatteners were supplemented with the enzyme Ronozyme VP. Apparent digestibility of nutrients was evaluated in a parallel experiment, using the same feeds on 18 barrows weighing about 40 kg (grower) and 80 kg (finisher). There was almost no difference in sow reproductive rates, litter weight and body weight of piglets on the first day of life were similar. Until 35 days of age piglets receiving faba bean grew faster than control ones. Control piglets grew fastest from 35 to 84 days of age, but differences were not significant. Enzyme supplement had a positive effect on body weight only from 56 to 84 days of piglet life. Digestibility of nutrients was lower in pigs fed with faba beans, especially in the grower period. Faba bean HT had lower nutrient digestibility in both periods of fattening. Almost all carcass traits were better in control pigs than in those fed with bean variety Bobas. Meat of these pigs had also the lowest content of unsaturated fatty acids and highest atherogenic indices. In sensory evaluation this meat had also the worst smell and taste. It can be stated that faba bean seeds, in moderate amounts, can partially replace soybean meal in feed for pigs, but some lowering of body weight gain and meat quality is possible especially when high-tannin varieties are used.

scholarly journals Effect of methionine supplementation on the growth performance of rabbit

2013 ◽  
Vol 42 (1) ◽  
pp. 40-43 ◽  
Author(s):  
S Yesmin ◽  
ME Uddin ◽  
R Chacrabati ◽  
M Al-Mamun
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Body Weight Gain ◽  
Basal Diet ◽  
Nutrient Digestibility ◽  
Control Group ◽  
Feed Conversion ◽  
Final Body Weight ◽  
Methionine Supplementation ◽  
Four Levels

The present study was conducted to evaluate the effect of different levels of methionine supplementation on feed intake, nutrient digestibility and growth performance of growing rabbit. Sixteen weaned crossbred New Zealand White (NZW) growing rabbits (30-35 d) were distributed into four treatment groups having four replications in each group using a Completely Randomized Design (CRD). Basal diet composed of green grass (dhal grass) and concentrate mixture which was offered ad libitum basis for 56 days period. Four levels of methionine such as 0.0% (control), 0.15%, 0.25%, and 0.35% were supplemented randomly to rabbits. Results showed that supplementation of methionine did not affect green grass intake. Cumulative as well as daily concentrate and DM intake were significantly (p<0.05) higher for all methionine groups than control group. Final body weight gain as well as daily, weekly and cumulative body weight gains were improved significantly with increasing level of methionine. It was found that methionine had significant (p<0.01) effect on digestibility of DM, CP, NFE and EE but CF digestibility did not differ significantly. Digestibility was improved with increasing the level of methionine. Feed conversion ratio also decreased significantly with methionine supplementation, and 0.25% methionine group showed the best performance among the four treatments. DOI: http://dx.doi.org/10.3329/bjas.v42i1.15777 Bang. J. Anim. Sci. 2013. 42 (1): 40 43

Evaluation of Exogenous Laccase Enzyme Treated Finger Millet Straw on Body Weight Gain, DM Intake and Nutrient Digestibility in Heifers

2021 ◽  
Author(s):  
Vidya Pradeep Kumar ◽  
Ramya G. Rao ◽  
A. Dhali ◽  
Vandana Thammiaha ◽  
Manpal Sridhar
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Finger Millet ◽  
Body Weight Gain ◽  
Test Group ◽  
Nutrient Digestibility ◽  
Control Group ◽  
Widespread Application ◽  
Body Weights ◽  
Effect Of Feeding

Background: Fungal laccases have widespread application in a number of biotechnological processes including the biodegradation of lignin. Their low yield in the native state limits their practical use in the deconstruction of lignocellulosic biomass for feeding ruminants. Enzymes in bulk quantities are required to treat biomass which has got greater product consistency and less lot to lot variations. The present study was an attempt to evaluate the effect of feeding finger millet straw treated with exogenous laccases in heifers.Methods: The effect of feeding exogenous laccases obtained from immobilized Schizophyllum commune (MTCC 11893) on body weight gain, dry matter intake and nutrient digestibility in heifers was evaluated in three groups of heifers (4-each) with body weights ranging between 275 ± 47.12 to 276.75 ± 64.48kg. The control group received ad lib. finger millet straw treated with only production media (GI). Test group 1 (GII) received ad lib. straw treated with laccase rich media in a 3:5 (w/v) ratio, while test group 2 (GIII) received ad lib. straw treated in a 4:5 (w/v) ratio. Result: After 14- days of feeding, gain in body weights for GI, GII and GIII were 277.9 ± 68.47; 277.50 ± 46.43 and 278.85 ± 37.22 respectively with an overall increase of 1.15, 4.25 and 3.60 kgs. No significant variation (P greater than 0.05) was observed with regard to DMD (%) between the groups which was 46 ± 5.8 for the control animals and 41±13.0 and 41± 3.4 in G2 and G3 groups. Though significant variations were observed digestibility studies proved inconclusive. Though preliminary results indicate that applying lignin degrading enzymes as feed supplements could enhance digestibility of crop residues in ruminants.

Evaluation of turmeric extract on performance indices impressed by induced aflatoxicosis in broiler chickens

2011 ◽  
Vol 27 (10) ◽  
pp. 956-960 ◽  
Author(s):  
Nader Rangsaz ◽  
Majid Gholami Ahangaran
Keyword(s):  
Body Weight ◽  
Broiler Chickens ◽  
Body Weight Gain ◽  
Curcuma Longa ◽  
Basal Diet ◽  
Control Group ◽  
Broiler Chicks ◽  
Feed Conversion ◽  
Performance Indices ◽  
Turmeric Extract

The purpose of this study was evaluation of ethanolic turmeric extract (ETE; Curcuma longa) effect on overall performance including body weight (BW), body weight gain (BWG), feed intake and feed conversion ratio (FCR) weekly and cumulative for a period of 4 weeks with 300 commercial broiler chicks (Ross strain). These chicks were randomly divided into four groups with three replicates of 15 chicks in each replicate. In group A, chickens were fed a basal diet, in group B, chickens were fed a basal diet plus 3 ppm productive aflatoxin. In group C, chickens consumed a basal diet plus 0.05% ETE and in group D, chickens received a basal diet with 0.05% ETE plus 3 ppm productive aflatoxin. Aflatoxin production by Aspergillus parasiticus (PTTC NO:1850) in maize was according to the Shotwell method. The results revealed that there were no significant differences in BW, BWG and FCR between groups fed turmeric at 0.05% and the control group. The supplement of ETE in a diet containing 3 ppm aflatoxin can significantly improve performance indices compared with the group that consumed aflatoxin alone. In conclusion, our results suggest that turmeric extract ( Curcuma longa) can provide protection against the negative effects of aflatoxin on performance of broiler chickens.

Growth performance and digestibility of nutrients by weaner rabbits (Oryctolagus cuniculus) fed diets containing varying levels of cowpea (Vigna unguiculata) milling waste

2020 ◽  
Vol 47 (3) ◽  
pp. 149-154
Author(s):  
A. A. Malik ◽  
Y. S. Kudu ◽  
M. Abdullahi ◽  
M. J. Ibrahim
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Feed Intake ◽  
Body Weight Gain ◽  
Control Diet ◽  
Nutrient Digestibility ◽  
Control Treatment ◽  
Crude Fibre ◽  
Final Body Weight ◽  
Dietary Treatments

Conventional feed resources for livestock are increasingly becoming more expensive, due to competition with man; hence nutritionists are searching for cheaper, locally-available alternatives. A total of forty-five (45) mixed sex weaner rabbits, aged 5 – 6 weeks, with average initial weights of between 694.42 and 761.10 g were used to investigate the effect of varying levels of cowpea milling waste (CMW) diets on their growth performance and nutrient digestibility. They were randomly allotted to five dietary treatments with nine rabbits per treatment. The control treatment (T1) contained 0 % CMW while treatments T2, T3, T4 and T5 had 10, 20, 30 and 40 % CMW dietary inclusion levels, respectively. Clean water and feed were offered ad libitum daily to the rabbits, and record of their feed intake and growth performance were taken for 12 weeks. At the end of the 11th week, a nutrient digestibility trial was carried out. Results show that there were no significant (P>0.05) differences in final body weight, body weight gain, total feed intake and mortality among the dietary treatments. Feed conversion ratio (FCR) for diets T4 (6.65) and T5 (6.66) containing 30 and 40 % CMW respectively, were as good as that of the control diet (6.11). Dry matter and crude protein digestibility showed no significant (P>0.05) difference across the treatments. Digestibility of crude fibre (72.64, 80.16, 84.04 and 80.90 % for T2, T3, T4 and T5 respectively), ether extract (95.98, 94.90, 96.04 and 94.38 % for T2, T3, T4 and T5 respectively), nitrogen free extract (94.30, 95.18, 93.58 and 94.90 % for T2, T3, T4 and T5 respectively), as well as total digestible nutrient (83.69, 76.11, 81.67 and 80.02 % for T2, T3, T4 and T5 respectively) of the test diets compared favourably with that of the control diet (72.94, 95.23, 96.04 and 80.47 % for CF, EE, NFE and TDN respectively). Hence, it can be concluded that CMW can be used safely as a protein source and included up to 40 % in weaner rabbit diets with no detrimental effect on their growth performance and nutrient digestibility.

L-Ascorbic Acid Addition to Chitosan Reduces Body Weight in Overweight Women

2014 ◽  
Vol 84 (1-2) ◽  
pp. 5-11 ◽  
Author(s):  
Eun Y. Jung ◽  
Sung C. Jun ◽  
Un J. Chang ◽  
Hyung J. Suh
Keyword(s):  
Ascorbic Acid ◽  
Body Weight ◽  
Fat Body ◽  
Body Weight Gain ◽  
Skinfold Thickness ◽  
The Body ◽  
Control Group ◽  
Percentage Body Fat ◽  
Overweight Women ◽  
Body Weights

Previously, we have found that the addition of L-ascorbic acid to chitosan enhanced the reduction in body weight gain in guinea pigs fed a high-fat diet. We hypothesized that the addition of L-ascorbic acid to chitosan would accelerate the reduction of body weight in humans, similar to the animal model. Overweight subjects administered chitosan with or without L-ascorbic acid for 8 weeks, were assigned to three groups: Control group (N = 26, placebo, vehicle only), Chito group (N = 27, 3 g/day chitosan), and Chito-vita group (N = 27, 3 g/day chitosan plus 2 g/day L-ascorbic acid). The body weights and body mass index (BMI) of the Chito and Chito-vita groups decreased significantly (p < 0.05) compared to the Control group. The BMI of the Chito-vita group decreased significantly compared to the Chito group (Chito: -1.0 kg/m2 vs. Chito-vita: -1.6 kg/m2, p < 0.05). The results showed that the chitosan enhanced reduction of body weight and BMI was accentuated by the addition of L-ascorbic acid. The fat mass, percentage body fat, body circumference, and skinfold thickness in the Chito and Chito-vita groups decreased more than the Control group; however, these parameters were not significantly different between the three groups. Chitosan combined with L-ascorbic acid may be useful for controlling body weight.

PENGARUH PEMBERIAN KOMBINASI EKSTRAK BUAH MENGKUDU (Morinda citrifolia L.) DAN KUNYIT (Curcuma longa) TERHADAP HISTOPATOLOGI GINJAL TIKUS WISTAR YANG DIINDUKSI ALLOXAN

2020 ◽  
Vol 5 (2) ◽  
pp. 319-327
Author(s):  
Pelastri Rahayu ◽  
◽  
Retno Hestiningsih ◽  
Martini Martini ◽  
Dwi Sutiningsih ◽  
...  
Keyword(s):  
Body Weight ◽  
Diabetic Nephropathy ◽  
Blood Glucose ◽  
Curcuma Longa ◽  
Morinda Citrifolia ◽  
Control Group ◽  
Type I ◽  
Turmeric Extract ◽  
Measurement Results ◽  
Diabetes Nephropathy

The prevalence of DM in Riskesdas in 2018 according to the Perkeni consensus in 2015 is higher than according to the Perkeni consensus in 2011, the prevalence was10.9%. The disease can develop into diabetes nephropathy, Increased prevalence of diabetic nephropathy directly proportional with an increase in diabetes prevalence. Diabetic nephropathy is a microvascular complication in diabetics that develops around 30% in patients with type I DM and about 40% in patients with type II DM. Turmeric extract has antioxidant and anti-inflammatory effects to prevent the bad development of diabetes nephropathy. This study looked at the effect of giving a combination of noni and turmeric extract on histopathology of alloxan-induced renal rats. A total of 25 mice were divided into 5 treatment groups, namely the PI group (250 mg / kgBB extract dose), PII group (500 mg / kgBB extract dose), PIII group (750 mg / kgBB extract dose), positive control group (glibenklamid) and negative control group (without extract and glibenklamid). The study used Post Test Only Group. The highest percentage decrease in blood glucose in the PI group was 56.11% and the lowest decrease in the PIII group was 24.12% with p = 0.012. The results of the study were not based on the number of extract doses. The measurement results of rat body weight and glomerular diameter were not affected by blood glucose level with p = 0.700 for body weight and p = 0.187 for glomerular measurement results.

scholarly journals Chronic photoperiodic manipulation induced chronodisruption upregulates HSP60 during early pro-atherogenic remodeling in thoracic aorta of C57BL/6J mice

2021 ◽  
Vol 82 (1) ◽  
Author(s):  
Kavita Shirsath ◽  
Apeksha Joshi ◽  
Aliasgar Vohra ◽  
Ranjitsinh Devkar
Keyword(s):  
Body Weight ◽  
Thoracic Aorta ◽  
Serum Lipid ◽  
Body Weight Gain ◽  
Hdl Cholesterol ◽  
Circadian Disruption ◽  
Control Group ◽  
Chow Diet ◽  
Heat Shock Protein 60 ◽  
Lipid Parameters

Abstract Background Circadian disruption is often associated with aggravation of atherosclerosis; however, the pathophysiological mechanisms underlying atherogenic initiation in normolipidemic diet remains unclear. Most of the studies done for understanding circadian disruption induced atherosclerosis have been carried out in murine model of hyperlipidemia induced atherosclerosis. The present study investigates pro-atherogenic events in response to chronic photoperiodic manipulation induced chronodisruption (PMCD) in C57BL/6J mice fed with laboratory chow diet. Results The results were compared with atherogenic initiation induced by high fat high fructose (HFHF) diet. The combined effects of HFHF and PMCD on atherogenic initiation were also investigated for possible synergy of both variants. The HFHF and HFHF+PMCD groups recorded increments in body weight gains and serum lipid parameters (TC, TG, LDL-cholesterol, VLDL) and a decrement in HDL-cholesterol as compared to the control group. However, PMCD group recorded body weight gain similar to that of the control group, but the serum lipid parameters (TG and VLDL) were significantly elevated and the HDL levels were lowered. However, prominent hypertrophic remodeling, higher collagen deposition, and elastin derangement, along with endothelial dysfunction, its activation, and macrophage infiltration, were observed in thoracic aorta of all the three experimental groups. But the mRNA and immunoblots of heat shock protein 60 (HSP60) in thoracic aorta was found to be maximum in PMCD followed by HFHF and HFHF+PMCD groups. Conclusion Laboratory chow feeding coupled with photoperiodic manipulation mediated chronodisruption overexpress HSP60 that in turn plays a central role in PMCD mediated pro-atherogenic remodeling in thoracic aorta of C57BL/6J mice.

scholarly journals Effects of Defatted Rice Bran Inclusion Level on Nutrient Digestibility and Growth Performance of Different Body Weight Pigs

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1374
Author(s):  
Bingbing Huang ◽  
Huangwei Shi ◽  
Li Wang ◽  
Lu Wang ◽  
Zhiqian Lyu ◽  
...  
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Rice Bran ◽  
Nutrient Digestibility ◽  
Growing Pigs ◽  
Neutral Detergent Fiber ◽  
Control Group ◽  
Defatted Rice Bran ◽  
Gross Energy ◽  
Stage 1

This study was conducted to determine the effects of low-protein diet prepared with different levels of defatted rice bran (DFRB) and weight stages on growth performance and nutrient digestibility of growing–finishing pigs. The animal experiment included three stages. A total of 240 growing pigs with an initial body weight of 28.06 ± 8.56 kg for stage 1 were allocated to five diets including one control group and four DFRB diets supplemented with 2.5%, 5%, 7.5% and 10% DFRB, respectively. The 192 crossbred pigs with initial body weights of 55.03 ± 7.31 kg and 74.55 ± 9.10 kg were selected for stage 2 and stage 3, respectively. Pigs were allocated to four diets including one control group and three DFRB diets supplemented with 10%, 15% and 20% DFRB, respectively. The results showed that with the increase in DFEB intake, the gain: feed was linearly increased (p < 0.05), and the average daily feed intake tended to linearly decrease (p = 0.06) in stage 1. Except for the apparent total tract digestibility (ATTD) of acid detergent fiber (ADF) in stage 3, levels of DFRB had significant effects on the ATTD of gross energy (GE), dry matter (DM), ash, neutral detergent fiber (NDF) and ADF in three weight stages. In stage 1, with the increase in levels of DFRB, the ATTD of NDF and hemicellulose were firstly increased and then decreased (p < 0.01). In stage 2, with the increasing levels of DFRB, the ATTD of DM, ash and cellulose were firstly increased and then decreased (p < 0.01). In stage 3, the ATTD of GE, DM, ash, NDF and hemicellulose decreased linearly with the increase in levels of DFRB (p < 0.01). Collectively, DFRB could be used as a replacement for corns and soybean meal, and weight stage is important to consider when adjusting the additive proportion.

Effects of the lipase inhibitor orlistat on intake and preference for dietary fat in rats

1996 ◽  
Vol 271 (1) ◽  
pp. R48-R54 ◽  
Author(s):  
K. Ackroff ◽  
A. Sclafani
Keyword(s):  
Body Weight ◽  
Dietary Fat ◽  
Body Weight Gain ◽  
Caloric Intake ◽  
Female Rats ◽  
Control Group ◽  
Fat Intake ◽  
Fat Absorption ◽  
Drug Induced ◽  
Dietary Fat Intake

Orlistat (Ols), a potent inhibitor of pancreatic lipase, was added to the fat source (1 or 4 mg Ols/g fat) of a macronutrient self-selection diet fed to adult female rats. The rats responded to the drug-induced reduction in fat absorption by decreasing their dietary fat intake and increasing their protein and carbohydrate intake in a dose-related manner. Total caloric intake also increased, but body weight gain was inhibited compared with the nondrug control group. When Ols was removed from the diet, nutrient selection, caloric intake, and body weight returned to control levels. In additional short-term experiments (30 min/day), rats developed a preference for a plain fat diet over an Ols-fat diet (4 mg/g fat) and also for a cue flavor paired with plain fat over a flavor paired with Ols-fat. Yet, when not given the choice, the rats consumed nearly as much Ols-fat as plain fat diet. These results indicate that, by reducing fat absorption, Ols reduced the attractiveness of dietary fat, although it did not make the fat diet aversive. In clinical use, lipase inhibitors may be effective in reducing dietary fat intake by reducing both the consumption and absorption of fat.

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