scholarly journals Antimicrobial activity of essential oils extracted from leaves of native Moroccan plants against clinical bacterial isolates

10.3823/819 ◽  
2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Fatima El Malki ◽  
Kamal Eddaraji ◽  
Rajae Alloudane ◽  
Hassane Greche ◽  
Haiat Essalmani ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Essential Oils ◽  
Bactericidal Effect ◽  
Antimicrobial Activities ◽  
Acinetobacter Baumanii ◽  
And Staphylococcus Aureus

Introduction: Medicinal plants are plentiful of bioactive molecules effective against multi-resistance bacteria. The aims of this study were to assess the in vitro antimicrobial activities of essential oils extracted from three Moroccan aromatic plants. Methodology: Analysis of essential oils of Origanum compactum, Rosmarinus officinalis and Pelargonium asperum, collected from different localities in Morocco, were performed using a GC-MS spectrophotometry. Antibacterial activity was evaluated in vitro for five clinical multi-resistant isolates. Results: Origanum showed strong antibacterial activity against tested strains except Pseudomonas aeruginosa while Rosmarinum showed a bactericidal effect against Acinetobacter baumanii, Escherichia coli and Staphylococcus aureus. Pelargonium presented only slight growth inhibition of Staphylococcus aureus on solid medium, but provided bactericidal effect against Acinetobacter baumanii and Staphylococcus aureus. Interestingly, fractions F7 and F8 of Pelargonium which represented only 0.3% and 0.1% of the total mass were found bactericidal respectively against Klebsiella pneumoniae and Pseudomonas aeruginosa. Conclusions: Ours results showed that the antimicrobial activities were variables depending on the chemical composition of essential oils, the fraction used and the microorganism tested.Essential oils fractionation allows detection of bioactive substances, especially those owning antimicrobial activity, present in small quantities.

scholarly journals In Vitro Bactericidal Activity of Human β-Defensin 3 against Multidrug-Resistant Nosocomial Strains

2006 ◽  
Vol 50 (2) ◽  
pp. 806-809 ◽  
Author(s):  
Giuseppantonio Maisetta ◽  
Giovanna Batoni ◽  
Semih Esin ◽  
Walter Florio ◽  
Daria Bottai ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Bactericidal Activity ◽  
Stenotrophomonas Maltophilia ◽  
Bactericidal Effect ◽  
Multidrug Resistant ◽  
Bacterial Strains ◽  
Gram Negative

ABSTRACT The antimicrobial activity of human β-defensin 3 (hBD-3) against multidrug-resistant clinical isolates of Staphylococcus aureus, Enterococcus faecium, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter baumannii was evaluated. A fast bactericidal effect (within 20 min) against all bacterial strains tested was observed. The presence of 20% human serum abolished the bactericidal activity of hBD-3 against gram-negative strains and reduced the activity of the peptide against gram-positive strains.

scholarly journals Characterization and Antimicrobial Activity of Erbium(III) Complexes of C-3 Substituted 2-hydroxy-1,4-naphthalenedione-1-oxime Derivatives

2001 ◽  
Vol 8 (3) ◽  
pp. 159-164 ◽  
Author(s):  
S. B. Jagtap ◽  
N. N. Patil ◽  
B. P. Kapadnis ◽  
B. A. Kulkarni
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Magnetic Susceptibility ◽  
Candida Albicans ◽  
Xanthomonas Campestris ◽  
Antimicrobial Activities ◽  
Diffusion Method ◽  
Oxime Derivatives

Erbium(III) complexes of 2-hydroxy-l,4-naphthalenedione-1-oxime and its C-3 substituted derivatives are synthesized and characterized by elemental analysis, thermogravimetric analysis, infrared spectroscopy, magnetic susceptibility measurements 2-hydroxy-1,4-naphthalenedione-1-oxime derivatives are analysed using H1 and C13 NMR spectroscopy. The molecular composition of the synthesized complexes is found to be [ML3(H2O)2]. The antimicrobial activity of these complexes is determined by well diffusion method against the target microorganisms- Staphylococcus aureus, Xanthomonas campestris, Pseudomonas aeruginosa, Candida albicans and Aspergillus niger. The antimicrobial activities of 2- hydroxy-1,4-naphthalenedione-1-oximes and their complexes are compared. It is observed that 2-hydroxy-1,4-naphthalenedione-l-oximes exhibit higher antifungal activity as compared to antibacterial activity. These activities are reduced upon complexation of these oximes with Erbium.

Antimicrobial Activity of Leaves Extracts of Tamarindus indica L. (Magyee)

2019 ◽  
Vol 31 (2) ◽  
pp. 125-130
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Petroleum Ether ◽  
Aqueous Extracts ◽  
Tamarindus Indica ◽  
E Coli ◽  
Ethanolic Extracts ◽  
And Staphylococcus Aureus

This study aimed to determine antimicrobial activity of extracts of Tamarindus indica L. leaves (Magyee). It was the laboratory-based quasi experimental study design. Study sites were the University of Pharmacy (Mandalay and Yangon) and the Department of Medical Research (Yangon). The leaves of Tamarindus indica L. were extracted with petroleum ether, ethanol and distilled water by successive Soxhlet extraction method. Physicochemical and phytochemical studies were conducted according to reference analytical procedures. In vitro antimicrobial activity of three extracts of Tamarindus indica L. leaves were studied on control strains of bacteria (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Klebsiella pneumoniae) by agar disc diffusion method. Phytochemical analysis of Tamarindus indica L. leaves showed the presence of alkaloids, amino acids, carbohydrates, flavonoids, glycosides, polyphenol, starches, steroids/terpenoids, tannins, reducing sugars and anthroquinone. Ethanolic and aqueous extracts exhibited significant antibacterial activities against Pseudomonas aeruginosa and Staphylococcus aureus. Both aqueous and ethanolic extracts possessed promising antibacterial activity on Pseudomonas aeruginosa and Staphylococcus aureus. This was an important finding upon pathogenic organisms causing food-borne diseases, skin and soft tissue infection. The petroleum ether extract did not show antibacterial activity against all tested organisms. With ethanolic extracts, the minimum inhibitory concentrations (MIC) results were 6.25 mg/ml for P. aeruginosa, S. aureus and 25 mg/ml for E. coli. For aqueous extracts, the MIC of P. aeruginosa and S. aureus were 12.5 mg/ml and K. pneumoniae was 25 mg/ml, respectively. Oral acute administration of 5000 mg/kg mice body weight of ethanolic and aqueous extracts of Tamarindus indica L. leaves resulted in no mortality. Therefore, the crude extracts from Tamarindus indica L. leaves had antimicrobial activity against K. pneumoniae, P. aeruginosa, S. aureus and E. coli.

scholarly journals Uji Aktivitas Antibakteri Ekstrak Etanol Umbi Batang Tumbuhan Sarang Semut (Myrmecodia Pendens Merr. & L. M. Perry) Terhadap Pseudomonas Aeruginosa Dan Staphylococcus Aureus

2017 ◽  
Author(s):  
Ardianti Febriana
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Minimum Inhibitory Concentration ◽  
Inhibitory Concentration ◽  
Phytochemical Screening ◽  
Gram Positive ◽  
Tetracycline Hcl ◽  
And Staphylococcus Aureus

AbstrakTumbuhan sarang semut (Myrmecodia pendens Merr. & L. M. Perry) secara empiris digunakan sebagai obat yang memiliki aktivitas antibakteri. Namun, belum pernah diteliti mengenai aktivitas antibakteri tersebut. Penelitian ini dilakukan untuk mengetahui aktivitas antibakteri umbi batang sarang semut (Myrmecodia pendens Merr. & L. M. Perry) terhadap bakteri Gram negatif dan Gram positif yaitu Pseudomonas aeruginosa dan Staphylococcus aureus, menentukan konsentrasi hambat tumbuh minimum (KHTM), dan nilai banding ak- tivitas antibakterinya terhadap tetrasiklin-HCl. Hasil pengujian aktivitas antibakteri umbi batang sarang semut menunjukkan bahwa ekstrak umbi batang sarang semut memiliki ak- tivitas antibakteri terhadap kedua bakteri tersebut. Konsentrasi hambat tumbuh minimum (KHTM) ekstrak umbi batang sarang semut (Myrmecodia pendens Merr. & L. M. Perry) terhadap Pseudomonas aeruginosa terletak pada konsentrasi 0,83 % , sedangkan pada Staph- ylococcus aureus terletak pada konsentrasi 0,8 %. Hasil uji banding ekstrak umbi batang sarang semut (Myrmecodia pendens Merr. & L. M. Perry) dengan tetrasiklin-HCl terhadap Pseudomonas aeruginosa dan Staphylococcus aureus berturut-turut sebesar 1 : 6,709 x 10-4 dan 1 : 1,038 x 10-5. Penapisan fitokimia menunjukkan bahwa ekstrak umbi batang sarang semut (Myrmecodia pendens Merr. & L. M. Perry) mengandung flavonoid dan polifenol.Kata kunci: Myrmecodia pendens Merr. & L. M. Perry, Aktivitas antibakteri, Pseudomo- nas, StaphylococcusABSTRACTThe ant plant (Myrmecodia pendens Merr. & L. M. Perry) is one of plant applied as tradi- tional medicine. Empirically, the tuber of the ant plant have antibacterial activity. However, the examination of antimicrobial activity from extract of the tuber has never been reported. The research was done to know the activity of antimcrobial againts Gram positive and Gram negatif bacteria such as Pseudomonas aeruginosa and Staphylococcus aureus, to determine Minimum Inhibitory Concentration (MIC) of the tuber, and comparative value antibacterial activity with tetracycline-HCl. The result revealed that the tuber of the ant plant (Myrmeco-dia pendens Merr. & L. M. Perry) has antibacterial activity againts those bacteria. The Min- imum Inhibitory Concentration of extract from the tuber of ant plant to Pseudomonas aeru- ginosa was in range 8,2x103-8,3x103 ppm of concentration, and to Staphylococcus aureus was in range 7,5x103-8x103 ppm of concentration. Comparative value of extract from the tuber of ant plant with tetracycline-HCl againts Pseudomonas aeruginosa and Staphylococ- cus aureus were respective 1:.6.709 x 10-4 and :1.038 x 10-5. Phytochemical screening showed that the extract of the tuber contains flavonoid and polifenol.Keywords: Myrmecodia pendens Merr. & L. M. Perry, Antibacterial activity, Pseudomonas, Staphylococcus

scholarly journals Synthesis and Evaluation of Some New Thiazolidin-4-One Derivatives as Potential Antimicrobial Agents

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
B. A. Baviskar ◽  
S. S. Khadabadi ◽  
S. L. Deore
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Antimicrobial Agents ◽  
Salmonella Typhi ◽  
Zone Of Inhibition ◽  
Structure Activity

A new series ofN-{4-methyl-5-[4-(4-oxo-2-phenyl(1,3-thiazolidin-3-yl)]-5-sulfanyl(1,2,4-triazol-3-yl)-1,3-thiazol-2-yl }acetamide (7a-l) was synthesized in order to determine their antimicrobial activity and feasible structure–activity relationships. The compounds were synthesized in good yield and the structures of all newly synthesized compounds were established on the basis of their IR,1HNMR, and elemental analysis. The synthesized compounds were testedin vitroantibacterial activity againstStaphylococcus aureus,Escherichia coli,Pseudomonas aeruginosaandSalmonella typhiand antifungal activity againstAspergillus niger,Candida albicansby measuring the zone of inhibition in mm.

scholarly journals Chemical Composition and Antibacterial Activity of Cupressus dupreziana A. Camus

2007 ◽  
Vol 2 (9) ◽  
pp. 1934578X0700200 ◽  
Author(s):  
Messaoud Ramdani ◽  
Oualida Rached ◽  
Hocine Laouer ◽  
Meriem El Koli ◽  
Takia Lograda
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Chemical Composition ◽  
Essential Oils ◽  
Diffusion Method ◽  
Germacrene D ◽  
And Staphylococcus Aureus

The essential oils obtained by hydrodistillation from the green branchlets of Cupressus dupreziana A. Camus growing wild in Tassili n'Ajjer (Algeria) were analyzed by GC and GC/MS. The main constituents of the essential oils were α-pinene (27.2% - 44.2%), germacrene D (16.2% - 27.2%) and Δ3-carene (14.2% - 26.7%). The oils showed insignificant activity on the growth of Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853) and Staphylococcus aureus (ATCC 25923), when investigated by the diffusion method.

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