AbstractIn this study, MWCNT-Al2O3 hybrid nanoparticles with a composition ratio of 50:50 in SAE50 base oil are used. This paper aims to describe the rheological behavior of hybrid nanofluid based on temperature, shear rate ($$\dot{\gamma })$$
γ
˙
)
and volume fraction of nanoparticles ($$\varphi$$
φ
) to present an experimental correlation model. Flowmetric methods confirm the non-Newtonian behavior of the hybrid nanofluid. The highest increase and decrease in viscosity ($${\mu }_{\rm nf}$$
μ
nf
) in the studied conditions are measured as 24% and − 17%, respectively. To predict the experimental data, the five-point-three-variable model is used in the response surface methodology with a coefficient of determination of 0.9979. Margin deviation (MOD) of the data is determined to be within the permissible limit of − 4.66% < MOD < 5.25%. Sensitivity analysis shows that with a 10% increase in $$\varphi$$
φ
at $$\varphi =$$
φ
=
1%, the highest increase in $${\mu }_{\rm nf}$$
μ
nf
of 34.92% is obtained.