The chapter provides an in-depth overview and analysis for developing policies and strategies for managing a pandemic based on information and data. While looking for the credibility of an information source, various parameters are subjected for considerations (i.e., infection and death rates per given time, availability of personal protective equipment [PPE], overall population attitude, current strategy response rate, society behaviors, outcomes of policies interventions for curbing the spread of the virus, and many more). To critically analyze pandemic information and data usage along with issues and challenges that arise in collecting, extracting, or using various forms of information and data for pandemic management, numerous national action plans, world health databases, pandemic monitoring smart applications, government published infection-to-death ratios, and health cloud services are interpreted and discussed.