Amidst the COVID-19 pandemic situation, the human race has entered the era of hope and transformation, and there is growing pressure and focus to raise awareness to adopt alternative interventions and sustainable practices to ensure gaining sound functioning of physiological organs. Can yoga and meditation promote clarity in thoughts and enhance alertness at work? Does practice of mudras help in improving concentration level of individuals? Do yoga and meditation help to improve the improve quality of life in general? The aim of this chapter is to help new practitioners, scholars, and employees to understand fitness mantra without stress and strain through Indian style of yoga and meditation. This chapter presents an overview of collection of research papers and articles written by yoga experts, saints, and researchers that have emphasized psychology, spirituality, and mentioned evidence for better mental health or effectiveness of yoga, meditation, and mudra interventions as tools for improving the overall personality and mental health of individuals.