To the development of optimal methods for licorice seeds growing (Glycyrrhiza glabra L.) in irrigated lands of the Republic of Karakalpakstan

The research was carried out at the Nukus branch of the Tashkent State Agrarian University.The article presents the results of research on the development of optimal methods for growing licorice (Glycyrrhiza glabra L.) from seeds on salinity lands of the Republic of Karakalpakstan. In particular, the optimal rates of application of potassium geohumate for soaking licorice seeds, the rate of washing during soil desalination, the rates of mineral fertilizers and irrigation have been determined. The study of the effect of potassium geohumate on seed germination showed that soaking licorice seeds in a 0.05% solution of potassium geohumate for 3 days followed by drying the seeds in the open air provided the best germination on the 30th day after sowing and amounted to 72.6%, while the germination of licorice in the variant with the use of 0.03% potassium geohumate solution was 38.6%. The germination of the control variant was only 22.3%. It has also been established that the optimal rate of mineral fertilization for licorice is the application of 300 kg/ha of superphosphate, 150 kg/ha of potassium and 100 kg/ha of ammonium nitrate for 8 irrigations with a rate of 600 m3/ha.

Medicinal Uses of Licorice (Glycyrrhiza glabra L.): A Comprehensive Review

Innumerable plants have been used widely as integral medicinal sources since the start of human civilization. The demand for herbal medicines is constantly increasing with time overtime. Licorice ( Glycyrrhiza glabra family Leguminosae) is one of the most used herbal plants in foods, in medicinal forms, and substantially researched on a worldwide scale. It was used as traditional and complementary medicine against innumerable ailments including allergies, liver toxicity, gastric ulcer, lung diseases, skin disorders, oral health problems including tooth decay, and inflammation. The constituents of licorice include various essential oils, sugars, inorganic salts, resins, amino acids, and nucleic acids. Biological activity has been observed to be portrayed by active compounds of licorice including triterpene, flavonoids, and saponins. In recent years, licorice has been widely researched to discover its benefits, constituents, and its mechanism of action. The review summarizes the therapeutic and pharmacological benefits of licorice and its uses in different health-related conditions along with its toxicity and maximum levels of licorice consumption.

Технология получения субстанции на основе флавоноидов надземной части Glycyrrhiza glabra

Разработана методика очистки флавоноидов, выделенных из надземной части солодки голой (Glycyrrhiza glabra L.). Установлено, что извлечение суммы флавоноидов из концентрированного и разбавленного водой экстракта необходимо проводить хлороформом не менее 6 раз, а из хлороформного экстракта — не менее 8 экстракций 5 % водным раствором Na2CO3. Предложена нейтрализация содового раствора 5 % раствором HCl до pH 6,5 – 7. Найдены оптимальные параметры осаждения суммы флавоноидов, которые заключаются в трехкратном переосаждении технического глацембрина 60 % этиловым спиртом. В результате исследований разработана технология получения субстанции глацембрина на основе флавоноидов надземной части Glycyrrhiza glabra, обладающей противовоспалительным, антигипоксическим и болеутоляющим действием. Предложен спектрофотометрический метод количественного определения суммы флавоноидов при длине волны 292 нм в пересчете на пиноцембрин.