The results of the study of the helminth fauna of 8 species fish of the lower reaches reservoirs of the Zarafshan River are presented - carp (Cyprinus carpio), crucian carp (Carassius auratus gibelio), roach (Rutilus rutilus), oriental bream (Abramis brama), pike perch (Stizostedion lucioperca), silver carp (Hypophthalmichthys molitrix), pike (Esox lucius), Turkestan barbel (Barbus capito conocephalus). 27 species of helminths were identified, including 12 species of cestodes (Caryophyllaeus laticeps Pallas, 1781; Caryophyllaeus fimbriceps Annenkova - Chlopina, 1919; Biacetabulum appendiculatum Szidat, 1937; Khawia sinensis Hsu, 1935; Bathybothrium rectangulum Bloch, 1782; Bothriocephalus opsariichthydis Yamaguti, 1934; Ligula intestinalis Linnaeus, 1758 larvae; Digramma interupta Rudolphi, 1810 larvae; Proteocephalus torulosus Batsch, 1786; Neogryporhynchus cheilanoristrotus Wedl, 1855 larvae; Gryporhynchus pusillus von Nordman, 1832 larvae; Valipora campylancristrota Rudolphi, 1819 larvae), 5 species of trematodes (Sanguinicola inermis Plehn, 1905; Orientocreadium siluri Bychowsky et Dubinina, 1954; Allocreadium isoporum Looss, 1894; Diplostomum spathaceum Rudolvae, 1832 lare; (Dioctophyme renale Goeze, 1782 larvae; Rhabdochona denudata Dujardin, 1845; Desmidocercella numidica Seurat, 1920 larvae; Camallanus truncatus Rudolphi, 1814; Camallanus lacustris Zoega, 1776; Philometra ovatachenko Zeder, 1803; 1779 larvae) and 2 species of acanthocephalus (Pomphorhynchus laevis Muller, 1776; Acantocephalus lucii Muller, 1776). This work includes the results of the research of the helminthes of the fish of waterbodies in the lowers of the Zarafshan River. As a result, the infection of fish with 27 species of helminthes, belonging to cestodes (12), trematodes (5), nematodes (8), and acanthocephalans (2) was established.