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2021 ◽  
Author(s):  
Cesare Cornoldi ◽  
David Giofrè ◽  
Irene Mammarella ◽  
Enrico Toffalini

Whether intellectually gifted children have a greater emotional response when tested is still unclear. This may be due to the marked heterogeneity of this particular population, and the fact that most studies lack the power to reduce the noise associated with this heterogeneity. The present study examined the relationship between performance and emotional response in 468,423 Italian fifth-graders taking a national test on mathematics and language. Analyses were performed using statistical models with polynomial terms. Special attention was paid to estimating the mean emotional response of the children who were gifted (1.5-2.5 standard deviations above the mean) or highly gifted (more than 2.5 standard deviations above the mean). The results showed that, although a lower emotional response correlated with a higher achievement, this relationship is nonlinear, and the estimates for gifted and highly gifted children were virtually the same. Girls showed a greater emotional response than boys on all levels of performance. The theoretical and practical implications of these findings are discussed.


2021 ◽  
Author(s):  
Annabel A Powell ◽  
Freja Kirsebom ◽  
Julia Stowe ◽  
Kelsey McOwat ◽  
Vanessa Saliba ◽  
...  

AbstractAdolescents in the UK were recommended to have their first dose of mRNA vaccine during a period of high community transmission due to the highly transmissible Delta variant, followed by a second dose at an extended interval of 8-12 weeks. We used national SARS-CoV-2 testing, vaccination and hospitalisation data to estimate vaccine effectiveness (VE) using a test-negative case-control design, against PCR-confirmed symptomatic COVID-19 in England. VE against symptomatic disease increased to 80% within two weeks of the first dose of BNT162b2 vaccine (higher than in adults aged 18-64 years) and then declines rapidly to 40% within 8 weeks (similar to adults). Early data in 16-17-year-olds also indicate high protection against hospitalisation and a rapid increase in VE against symptomatic COVID-19 after the second dose. Our data highlight the importance of the second vaccine dose for protection against symptomatic COVID-19 and raise important questions about the objectives of an adolescent immunisation programme. If prevention of infection is the primary aim, then regular COVID-19 vaccine boosters will be required.


Author(s):  
Tina Lavigne ◽  
Brecht De Tavernier ◽  
Niels Van Regenmortel ◽  
Wouter De Tavernier ◽  
Jan Christiaen ◽  
...  

Abstract Introduction: There is evidence to suggest that patients delayed seeking urgent medical care during the first wave of the coronavirus disease 2019 (COVID-19) pandemic. A delay in health-seeking behavior could increase the disease severity of patients in the prehospital setting. The combination of COVID-19-related missions and augmented disease severity in the prehospital environment could result in an increase in the number and severity of physician-staffed prehospital interventions, potentially putting a strain on this highly specialized service. Study Objective: The aim was to investigate if the COVID-19 pandemic influences the frequency of physician-staffed prehospital interventions, prehospital mortality, illness severity during prehospital interventions, and the distribution in the prehospital diagnoses. Methods: A retrospective, multicenter cohort study was conducted on prehospital charts from March 14, 2020 through April 30, 2020, compared to the same period in 2019, in an urban area. Recorded data included demographics, prehospital diagnosis, physiological parameters, mortality, and COVID-status. A modified National Health Service (NHS) National Early Warning Score (NEWS) was calculated for each intervention to assess for disease severity. Data were analyzed with univariate and descriptive statistics. Results: There was a 31% decrease in physician-staffed prehospital interventions during the period under investigation in 2020 as compared to 2019 (2019: 644 missions and 2020: 446 missions), with an increase in prehospital mortality (OR = 0.646; 95% CI, 0.435 – 0.959). During the study period, there was a marked decrease in the low and medium NEWS groups, respectively, with an OR of 1.366 (95% CI, 1.036 – 1.802) and 1.376 (0.987 – 1.920). A small increase was seen in the high NEWS group, with an OR of 0.804 (95% CI, 0.566 – 1.140); 2019: 80 (13.67%) and 2020: 69 (16.46%). With an overall decrease in cases in all diagnostic categories, a significant increase was observed for respiratory illness (31%; P = .004) and cardiac arrest (54%; P < .001), combined with a significant decrease for intoxications (-58%; P = .007). Due to the national test strategy at that time, a COVID-19 polymerase chain reaction (PCR) result was available in only 125 (30%) patients, of which 20 (16%) were positive. Conclusion: The frequency of physician-staffed prehospital interventions decreased significantly. There was a marked reduction in interventions for lower illness severity and an increase in higher illness severity and mortality. Further investigation is needed to fully understand the reasons for these changes.


Epidemiologia ◽  
2021 ◽  
Vol 2 (4) ◽  
pp. 540-552
Author(s):  
Peter Kamp Busk ◽  
Thomas Birk Kristiansen ◽  
Allan Engsig-Karup

During the COVID-19 pandemic, Denmark has pursued a mass testing strategy culminating in the testing of 12.167 individuals per 100,000 inhabitants per day during the spring of 2021. The strategy included free access to COVID-19 testing, and since 2021, compulsory documentation for negative tests or vaccination has been required for access to workplace, educational institutions, restaurants, and many other places. Testing and subsequent isolation if testing was positive were voluntary. The present study provides an analysis of whether testing frequency in Denmark showed any correlation to hospitalizations throughout the relevant stages of the pandemic. Mass testing was found not to correlate significantly with the number of hospitalizations during the pandemic. Interestingly, during the highest level of testing in spring 2021 the fraction of positive tests increased slightly; thus, the Danish mass testing strategy, at its best, failed to reduce the prevalence of COVID-19. Furthermore, the relationship between positives in antigen testing and in rt-PCR testing indicated that many patients were not tested early in their infection when the risk of transmission was at the highest. In conclusion, the Danish mass testing strategy for COVID-19 does not appear to have a detectable correlation to the number of hospitalizations due to COVID-19.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
I Kit Cheng ◽  
Johannes Heyl ◽  
Nisha Lad ◽  
Gabriel Facini ◽  
Zara Grout

AbstractIn the absence of nationwide mass testing for an emerging health crisis, alternative approaches could provide necessary information efficiently to aid policy makers and health bodies when dealing with a pandemic. The following work presents a methodology by which Twitter data surrounding the first wave of the COVID-19 pandemic in the UK is harvested and analysed using two main approaches. The first is an investigation into localized outbreak predictions by developing a prototype early-warning system using the distribution of total tweet volume. The temporal lag between the rises in the number of COVID-19 related tweets and officially reported deaths by Public Health England (PHE) is observed to be 6–27 days for various UK cities which matches the temporal lag values found in the literature. To better understand the topics of discussion and attitudes of people surrounding the pandemic, the second approach is an in-depth behavioural analysis assessing the public opinion and response to government policies such as the introduction of face-coverings. Using topic modelling, nine distinct topics are identified within the corpus of COVID-19 tweets, of which the themes ranged from retail to government bodies. Sentiment analysis on a subset of mask related tweets revealed sentiment spikes corresponding to major news and announcements. A Named Entity Recognition (NER) algorithm is trained and applied in a semi-supervised manner to recognise tweets containing location keywords within the unlabelled corpus and achieved a precision of 81.6%. Overall, these approaches allowed extraction of temporal trends relating to PHE case numbers, popular locations in relation to the use of face-coverings, and attitudes towards face-coverings, vaccines and the national ‘Test and Trace’ scheme.


2021 ◽  
pp. 001698622110429
Author(s):  
Cesare Cornoldi ◽  
David Giofrè ◽  
Irene Cristina Mammarella ◽  
Enrico Toffalini

Whether intellectually gifted children have a greater emotional response when tested is still unclear. This may be due to the marked heterogeneity of this particular population, and the fact that most studies lack the power to reduce the noise associated with this heterogeneity. The present study examined the relationship between performance and emotional response in 468,423 Italian fifth-graders taking a national test on mathematics and language. Analyses were performed using statistical models with polynomial terms. Special attention was paid to estimating the mean emotional response of the children who were gifted (1.5-2.5 standard deviations above the mean) or highly gifted (more than 2.5 standard deviations above the mean). The results showed that, although a lower emotional response correlated with a higher achievement, this relationship is nonlinear, and the estimates for gifted and highly gifted children were virtually the same. Girls showed a greater emotional response than boys on all levels of performance. The theoretical and practical implications of these findings are discussed.


Author(s):  
ALEXANDER BOR ◽  
MICHAEL BANG PETERSEN

Why are online discussions about politics more hostile than offline discussions? A popular answer argues that human psychology is tailored for face-to-face interaction and people’s behavior therefore changes for the worse in impersonal online discussions. We provide a theoretical formalization and empirical test of this explanation: the mismatch hypothesis. We argue that mismatches between human psychology and novel features of online environments could (a) change people’s behavior, (b) create adverse selection effects, and (c) bias people’s perceptions. Across eight studies, leveraging cross-national surveys and behavioral experiments (total N = 8,434), we test the mismatch hypothesis but only find evidence for limited selection effects. Instead, hostile political discussions are the result of status-driven individuals who are drawn to politics and are equally hostile both online and offline. Finally, we offer initial evidence that online discussions feel more hostile, in part, because the behavior of such individuals is more visible online than offline.


2021 ◽  
Author(s):  
Peter Kamp Busk ◽  
Thomas Birk Kristiansen ◽  
Allan Engsig-Karup

During the Covid-19 pandemic, Denmark has pursued a unique mass testing strategy culminating in testing of more than 8,000 citizens per 100,000 inhabitants per day in the Spring 2021. The strategy includes free access to Covid-19 testing and since 2021, compulsory documentation for negative test or vaccination for access to workplace, educational institutions, restaurants, and many other places. In the present study we analysed the effect of the Danish mass testing strategy throughout relevant stages of the pandemic. Mass testing was found not to have impact on the number of hospitalizations during the pandemic. Furthermore, during the highest level of testing in the spring 2021 the fraction of positive tests increased slightly on comparable days indicating that mass testing at best, did not reduce the prevalence of Covid-19. The relationship between positives in antigen testing and in PCR testing indicated that many patients are not tested early in their infection where the risk of transmission is highest. A likely explanation for the lack of impact of mass testing on hospitalizations and infections is that the testing increases risk-behaviour of the tested persons and that a high fraction of false negatives at low Covid-19 prevalence combined with increased risk-behaviour outweighs beneficial effects of mass testing.


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