A variable valvetrain system is the key part of the variable stroke engine (VSE), which could achieve higher power performance and low-speed torque. An innovative axial shift valvetrain system (ASVS) was put forward to meet the air-charging requirements of a 2/4-stroke engine and complete a changeover within one working cycle. Two sets of intake and exhaust cam profiles for both intake and exhaust sides in the 2/4-stoke mode were designed for 2/4-stoke modes. Furthermore, a simulation model based on ADAMS was established to evaluate the dynamic valve motion and the contact force at different engine speeds. The dynamic simulation results show that the valve motion characteristics meet the challenges at the target engine speed of 3000 r/min. In two-stroke mode, the maximum intake valve lift could achieve 7.3 mm within 78°CaA, and the maximum exhaust valve lift could achieve 7.5 within 82°CaA on the exhaust side. In four-stroke mode, the maximum intake valve lift can achieve 8.8 mm within 140°CaA, and the maximum exhaust valve lift can achieve 8.4 mm within 140°CaA. The valve seating speeds are less than 0.3 m/s in both modes, and the fullness coefficients are more than 0.5 and 0.6 in the 2-stroke and 4-stroke mode, respectively. At the engine speed of 3000 r/min, the contact force on each component is acceptable, and the stress between cam and roller can meet the material requirement.