Postscript ot vitamin A acid therapy for acne vulgaris

1973 ◽  
Vol 107 (2) ◽  
pp. 296b-296
Author(s):  
A. M. Kligman
Keyword(s):  
Vitamin A ◽  
Acne Vulgaris ◽  
Acid Therapy ◽  
Vitamin A Acid

Postscript to Vitamin A Acid Therapy for Acne Vulgaris

1973 ◽  
Vol 107 (2) ◽  
pp. 296
Author(s):  
Albert M. Kligman
Keyword(s):  
Vitamin A ◽  
Acne Vulgaris ◽  
Acid Therapy ◽  
Vitamin A Acid

Effect of 0.01% Vitamin A Acid Milky Lotion on Acne Vulgaris

1973 ◽  
Vol 35 (6) ◽  
pp. 794-797 ◽  
Author(s):  
Yasushi WATANABE
Keyword(s):  
Vitamin A ◽  
Acne Vulgaris ◽  
Vitamin A Acid

Topical Tretinoin, Vitamin A Acid (Airol®) in Acne vulgaris

Dermatology ◽  
1974 ◽  
Vol 148 (2) ◽  
pp. 82-89 ◽  
Author(s):  
J.V. Christiansen ◽  
E. Gadborg ◽  
K. Ludvigsen ◽  
C.H.K. Meier ◽  
A. Nørholm ◽  
...  
Keyword(s):  
Vitamin A ◽  
Acne Vulgaris ◽  
Topical Tretinoin ◽  
Vitamin A Acid

Topical Application of Vitamin A Acid in Acne Vulgaris

1974 ◽  
Vol 67 (6) ◽  
pp. 683-687 ◽  
Author(s):  
LINWOOD G. BRADFORD ◽  
LEOPOLDO F. MONTES
Keyword(s):  
Vitamin A ◽  
Topical Application ◽  
Acne Vulgaris ◽  
Vitamin A Acid

Studies on the Mechanism of Action of Topical Benzoyl Peroxide and Vitamin A Acid in Acne Vulgaris

1974 ◽  
Vol 1 (5) ◽  
pp. 191-200 ◽  
Author(s):  
James E. Fulton ◽  
A. Farzad-Bakshandeh ◽  
Sara Bradley
Keyword(s):  
Vitamin A ◽  
Benzoyl Peroxide ◽  
Mechanism Of Action ◽  
Acne Vulgaris ◽  
Vitamin A Acid

Clinical Effect of 0.01% Vitamin A Acid Milky Lotion on Acne Vulgaris

1973 ◽  
Vol 35 (6) ◽  
pp. 781-785 ◽  
Author(s):  
Masakazu ASAHI ◽  
Shoji TOSHITANI ◽  
Setsuko UEDA
Keyword(s):  
Vitamin A ◽  
Clinical Effect ◽  
Acne Vulgaris ◽  
Vitamin A Acid

VITAMIN A ACID IN ACNE VULGARIS: A REVIEW

InPharma ◽  
1978 ◽  
Vol 120 (1) ◽  
pp. 17-18
Keyword(s):  
Vitamin A ◽  
Acne Vulgaris ◽  
Vitamin A Acid

Topical vitamin A acid in acne vulgaris

1969 ◽  
Vol 99 (4) ◽  
pp. 469-476 ◽  
Author(s):  
A. M. Kligman
Keyword(s):  
Vitamin A ◽  
Acne Vulgaris ◽  
Vitamin A Acid

Tretinoin in acne: retin-A

1973 ◽  
Vol 11 (13) ◽  
pp. 49-50
Keyword(s):  
Vitamin A ◽  
Acne Vulgaris ◽  
Topical Therapy ◽  
Alcoholic Solution ◽  
Bacterial Colonisation ◽  
Bacterial Decomposition ◽  
Sebum Production ◽  
Vitamin A Acid ◽  
Oral Doses

The development of acne is usually associated with increased sebum production (seborrhoea) and obstruction of the pilo-sebaceous duct. One result of this obstruction is bacterial colonisation of the glands and ducts; bacterial decomposition of sebum produces irritant substances, perhaps fatty acids, and eventually the gland ruptures liberating the sebum into the dermis, producing the inflammatory response which is a feature of acne. At present there is no satisfactory way of reducing sebum production. The bacteriological and biochemical changes secondary to obstruction can be modified with long-term use of an oral tetracycline, 250 mg once or twice daily for three months or longer. Attempts to influence the obstruction problem often succeed only partially. Such attempts include the use of ultraviolet radiation, sulphur, resorcinol (Acnil - Fisons; Eskamel - SKF), Brasivol (Stiefel), benzoyl peroxide (Benoxyl - Stiefel), Quinoderm (Quinoderm Co.), and removing blackheads mechanically. However some safe topical therapy is needed which will effectively banish blackheads, whiteheads and papules, especially in those patients whose acne is not adequately controlled by the traditional peeling agents. After large oral doses of vitamin A were found effective in acne vulgaris,1 it was tried topically, and recently vitamin A acid, tretinoin, has been introduced as Retin-A (Ortho). This is an alcoholic solution containing 0.025% tretinoin.

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