Multivalent Effect in Glycosidase Inhibition: The End of the Beginning

2019 ◽  
Vol 20 (1) ◽  
pp. 10-22 ◽  
Author(s):  
Philippe Compain
Keyword(s):  
Multivalent Effect ◽  
Glycosidase Inhibition

The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Valency, Peripheral Ligand Structure, and Topology with Cyclodextrin-Based Iminosugar Click Clusters

ChemBioChem ◽  
2013 ◽  
Vol 14 (15) ◽  
pp. 2038-2049 ◽  
Author(s):  
Camille Decroocq ◽  
Antoine Joosten ◽  
Raphaël Sergent ◽  
Teresa Mena Barragán ◽  
Carmen Ortiz Mellet ◽  
...  
Keyword(s):  
Ligand Structure ◽  
And Topology ◽  
Multivalent Effect ◽  
Glycosidase Inhibition

Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect

2010 ◽  
Vol 122 (33) ◽  
pp. 5889-5892 ◽  
Author(s):  
Philippe Compain ◽  
Camille Decroocq ◽  
Julien Iehl ◽  
Michel Holler ◽  
Damien Hazelard ◽  
...  
Keyword(s):  
Multivalent Effect ◽  
Glycosidase Inhibition

ChemInform Abstract: Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect.

ChemInform ◽  
2010 ◽  
Vol 41 (45) ◽  
pp. no-no
Author(s):  
Philippe Compain ◽  
Camille Decroocq ◽  
Julien Iehl ◽  
Michel Holler ◽  
Damien Hazelard ◽  
...  
Keyword(s):  
Multivalent Effect ◽  
Glycosidase Inhibition

The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Architectural Parameters with Cyclodextrin-based Iminosugar Click Clusters

2011 ◽  
Vol 17 (49) ◽  
pp. 13825-13831 ◽  
Author(s):  
Camille Decroocq ◽  
David Rodríguez-Lucena ◽  
Virginie Russo ◽  
Teresa Mena Barragán ◽  
Carmen Ortiz Mellet ◽  
...  
Keyword(s):  
Multivalent Effect ◽  
Glycosidase Inhibition

Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect

2010 ◽  
Vol 49 (33) ◽  
pp. 5753-5756 ◽  
Author(s):  
Philippe Compain ◽  
Camille Decroocq ◽  
Julien Iehl ◽  
Michel Holler ◽  
Damien Hazelard ◽  
...  
Keyword(s):  
Multivalent Effect ◽  
Glycosidase Inhibition

scholarly journals Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels

2016 ◽  
Vol 22 (15) ◽  
pp. 5151-5155 ◽  
Author(s):  
Mathieu L. Lepage ◽  
Jérémy P. Schneider ◽  
Anne Bodlenner ◽  
Alessandra Meli ◽  
Francesco De Riccardis ◽  
...  
Keyword(s):  
Multivalent Effect ◽  
Glycosidase Inhibition

Fluorinated and Conformationally Fixed Derivatives of l-HomoDMDP: Synthesis and Glycosidase Inhibition

2015 ◽  
Vol 80 (10) ◽  
pp. 5151-5158 ◽  
Author(s):  
Yi-Xian Li ◽  
Yousuke Shimada ◽  
Isao Adachi ◽  
Atsushi Kato ◽  
Yue-Mei Jia ◽  
...  
Keyword(s):  
Derivatives Of ◽  
Glycosidase Inhibition

Gem-difluoromethylated and trifluoromethylated derivatives of DMDP-related iminosugars: synthesis and glycosidase inhibition

2016 ◽  
Vol 14 (7) ◽  
pp. 2249-2263 ◽  
Author(s):  
Yi-Xian Li ◽  
Kyoko Kinami ◽  
Yuki Hirokami ◽  
Atsushi Kato ◽  
Jia-Kun Su ◽  
...  
Keyword(s):  
Cyclic Nitrones ◽  
Derivatives Of ◽  
Glycosidase Inhibition

Gem-difluoromethylated and trifluoromethylated derivatives of DMDP-related iminosugars have been synthesized from cyclic nitrones and assayed against various glycosidases.

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