Ligand Design for Asymmetric Catalysis: Combining Mechanistic and Chemoinformatics Approaches

New Directions in the Modeling of Organometallic Reactions - Topics in Organometallic Chemistry ◽

10.1007/3418_2020_47 ◽

2020 ◽

pp. 153-189

Author(s):

Ruchuta Ardkhean ◽

Stephen P. Fletcher ◽

Robert S. Paton

Keyword(s):

Asymmetric Catalysis ◽

Ligand Design

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ChemInform Abstract: Planar Chiral Mimetics. A New Approach to Ligand Design for Asymmetric Catalysis.

ChemInform ◽

10.1002/chin.200108042 ◽

2001 ◽

Vol 32 (8) ◽

pp. no-no

Author(s):

Geraint Jones ◽

David C. D. Butler ◽

Christopher J. Richards

Keyword(s):

Asymmetric Catalysis ◽

Ligand Design ◽

New Approach

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Concepts for ligand design in asymmetric catalysis: a study of chiral amino thiol ligands

Tetrahedron Asymmetry ◽

10.1016/s0957-4166(98)00344-9 ◽

1998 ◽

Vol 9 (19) ◽

pp. 3461-3490 ◽

Cited By ~ 40

Author(s):

James C. Anderson ◽

Rachel Cubbon ◽

Michael Harding ◽

Daniel S. James

Keyword(s):

Asymmetric Catalysis ◽

Ligand Design ◽

Amino Thiol ◽

Thiol Ligands

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An N–Ar axially chiral mimetic. A new approach to ligand design for asymmetric catalysis

Tetrahedron ◽

10.1016/s0040-4020(02)00507-0 ◽

2002 ◽

Vol 58 (26) ◽

pp. 5209-5214 ◽

Cited By ~ 24

Author(s):

Kazuhiro Kondo ◽

Kumiko Kazuta ◽

Hiroko Fujita ◽

Yohko Sakamoto ◽

Yasuoki Murakami

Keyword(s):

Asymmetric Catalysis ◽

Ligand Design ◽

New Approach ◽

Axially Chiral

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Planar chiral mimetics. A new approach to ligand design for asymmetric catalysis

Tetrahedron Letters ◽

10.1016/s0040-4039(00)01715-9 ◽

2000 ◽

Vol 41 (48) ◽

pp. 9351-9354 ◽

Cited By ~ 13

Author(s):

Geraint Jones ◽

David C.D Butler ◽

Christopher J Richards

Keyword(s):

Asymmetric Catalysis ◽

Ligand Design ◽

New Approach

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ChemInform Abstract: Concepts for Ligand Design in Asymmetric Catalysis: A Study of Chiral Amino Thiol Ligands.

ChemInform ◽

10.1002/chin.199918027 ◽

2010 ◽

Vol 30 (18) ◽

pp. no-no

Author(s):

James C. Anderson ◽

Rachel Cubbon ◽

Michael Harding ◽

Daniel S. James

Keyword(s):

Asymmetric Catalysis ◽

Ligand Design ◽

Abstract Concepts ◽

Amino Thiol ◽

Thiol Ligands

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ChemInform Abstract: An N-Ar Axially Chiral Mimetic. A New Approach to Ligand Design for Asymmetric Catalysis.

ChemInform ◽

10.1002/chin.200243036 ◽

2010 ◽

Vol 33 (43) ◽

pp. no-no

Author(s):

Kazuhiro Kondo ◽

Kumiko Kazuta ◽

Hiroko Fujita ◽

Yohko Sakamoto ◽

Yasuoki Murakami

Keyword(s):

Asymmetric Catalysis ◽

Ligand Design ◽

New Approach ◽

Axially Chiral

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Asymmetric catalysis: Chirally inspired

Nature China ◽

10.1038/nchina.2008.28 ◽

2008 ◽

Author(s):

Anne Pichon

Keyword(s):

Asymmetric Catalysis

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Faculty Opinions recommendation of Asymmetric Catalysis in Diversity-Oriented Organic Synthesis: Enantioselective Synthesis of 4320 Encoded and Spatially Segregated Dihydropyrancarboxamides We thank the National Institute of General Medical Sciences (GM-52067) for support of this research, and Dr. John Tallarico and Max Narovlyansky at the ICCB for generously providing resin for the library synthesis. We thank Dr. Helen Blackwell and Lucy Pérez for expert help with library encoding. We are grateful to Prof. Eric Jacobsen and Prof. Scott Denmark for the use of their chiral stationary phase high pressure liquid chromatograph and supercritical fluid chromatograph, respectively. The Harvard ICCB is supported by Merck & Co., Merck KGaA, the Keck Foundation, and the National Cancer Institute. R.A.S. is a Research Associate and S.L.S. is an Investigator with the Howard Hughes Medical Institute at the Department of Chemistry and Chemical Biology, Harvard University.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1003104.32305 ◽

2002 ◽

Author(s):

Stefan Bräse

Keyword(s):

Asymmetric Catalysis ◽

Chiral Stationary Phase ◽

Howard Hughes Medical Institute ◽

Harvard University ◽

Medical Institute ◽

Library Synthesis ◽

Medical Sciences ◽

Liquid Chromatograph ◽

Research Associate ◽

High Pressure Liquid Chromatograph

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Faculty Opinions recommendation of Ligand Design to Acquire Specificity to Intended G-Quadruplex Structures.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.733716143.793557206 ◽

2019 ◽

Author(s):

Jonathan Chaires

Keyword(s):

Ligand Design ◽

G Quadruplex

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Class A GPCRs: Structure, Function, Modeling and Structure-based Ligand Design

Current Pharmaceutical Design ◽

10.2174/1381612823666170710151255 ◽

2017 ◽

Vol 23 (29) ◽

Cited By ~ 13

Author(s):

Xiaojing Cong ◽

Jeremie Topin ◽

Jerome Golebiowski

Keyword(s):

Structure Function ◽

Ligand Design ◽

Class A

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