Optimizing Donor and Cord Blood Unit Selection for Banking and Transplantation

2014 ◽  
pp. 59-71 ◽  
Author(s):  
Kristin M. Page ◽  
Joanne Kurtzberg
Keyword(s):  
Cord Blood ◽  
Unit Selection ◽  
Blood Unit ◽  
Cord Blood Unit ◽  
Selection For

scholarly journals Optimization of the criteria for cord blood unit selection for transplantation in recipients of the different age groups: current view and prospects in Ukraine

2020 ◽  
Vol 8 (2) ◽  
Author(s):  
P. Nemtinov ◽  
◽  
A. Ustymenko ◽  
G. Lobyntseva ◽  
L. Panchenko ◽  
...  
Keyword(s):  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Age Groups ◽  
Blood Bank ◽  
Unit Selection ◽  
Blood Unit ◽  
Cord Blood Bank ◽  
Cord Blood Unit ◽  
Selection For

Umbilical cord blood has been widely used to treat both malignant and non-malignant hematological diseases for over 30 years. During this time, more than 40,000 successful hematopoietic stem cell (HSC) transplantations of umbilical cord blood have been performed. However, today in Ukraine there is no public umbilical cord blood bank established for unrelated HSC transplantation to patients with oncohematological disorders (both children and adults). In this regard, the HSC units must be purchased abroad or the patients are sent to foreign clinics for high-cost treatment. The organization of a public umbilical cord blood bank in Ukraine would help in a short time to meet the needs of patients with oncohematological disorders for donor HSCs for unrelated transplantation and save significant funds for the treatment of patients abroad. According to the experience of the world's leading oncohematological centers, when it is impossible to find either a related or haploidentical donor or in all available registries – a unrelated transplant, the search continues in the registers of public cord blood banks and an umbilical cord blood unit that matches the criteria is usually found. The optimal choice of umbilical cord blood unit is crucial to maximize the likelihood of successful transplant engraftment and recipient survival after the transplantation, so the criteria for cord blood unit selection for unrelated transplantation are a bit broader than those used when matching donor-recipient pairs. The review presents the main criteria for cord blood unit selection according to the assessment of its quality, cell dose, HLA matching for unrelated transplantation to recipients of different age groups in accordance with international guidelines developed by the National Marrow Donor Program (NMDP), USA Center for International Blood and Brain Transplantation Research (CIBMTR), in collaboration with the NMDP Council Advisory Group, as well as in accordance with the American Society for Transplantation and Cellular Therapy (ASTCT) and the Seventh Edition of the NetCord-FACT International Standards for Cord Blood Collection, Banking, and Release for Administration.

scholarly journals Optimizing donor selection for public cord blood banking: influence of maternal, infant, and collection characteristics on cord blood unit quality

Transfusion ◽  
2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Kristin M. Page ◽  
Adam Mendizabal ◽  
Brigid Betz-Stablein ◽  
Stephen Wease ◽  
Kevin Shoulars ◽  
...  
Keyword(s):  
Cord Blood ◽  
Donor Selection ◽  
Blood Banking ◽  
Blood Unit ◽  
Cord Blood Unit ◽  
Cord Blood Banking ◽  
Selection For

scholarly journals Guidelines for Cord Blood Unit Selection

2020 ◽  
Vol 26 (12) ◽  
pp. 2190-2196
Author(s):  
Ioannis Politikos ◽  
Eric Davis ◽  
Melissa Nhaissi ◽  
John E. Wagner ◽  
Claudio G. Brunstein ◽  
...  
Keyword(s):  
Cord Blood ◽  
Unit Selection ◽  
Blood Unit ◽  
Cord Blood Unit

Combined impact of HLA-allele matching and the CD34-positive cell dose on optimal unit selection for single-unit cord blood transplantation in adults

2021 ◽  
pp. 1-10
Author(s):  
Toshio Yabe ◽  
Masahiro Satake ◽  
Takeshi Odajima ◽  
Naoko Watanabe-Okochi ◽  
Fumihiro Azuma ◽  
...  
Keyword(s):  
Cord Blood ◽  
Single Unit ◽  
Cord Blood Transplantation ◽  
Unit Selection ◽  
Cell Dose ◽  
Blood Transplantation ◽  
Selection For ◽  
Combined Impact

scholarly journals Is there an expiration date for a cord blood unit in storage?

2014 ◽  
Vol 49 (8) ◽  
pp. 1109-1112 ◽  
Author(s):  
S Parmar ◽  
M de Lima ◽  
L Worth ◽  
D Petropoulos ◽  
D Lee ◽  
...  
Keyword(s):  
Cord Blood ◽  
Expiration Date ◽  
Blood Unit ◽  
Cord Blood Unit
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