Anticonvulsant Agents: Cannabidiol and Fenfluramine

2021 ◽  
pp. 1-15
Author(s):  
Adam Strzelczyk ◽  
Katharina Frey ◽  
Felix Rosenow ◽  
Susanne Schubert-Bast
Keyword(s):  
Anticonvulsant Agents

Synthesis, in silico, in vitro and in vivo evaluations of isatin aroylhydrazones as highly potent anticonvulsant agents

2021 ◽  
pp. 104943
Author(s):  
Saeed Emami ◽  
Mehdi Valipour ◽  
Fatemeh Kazemi Komishani ◽  
Fatemehsadat Sadati-Ashrafi ◽  
Maria Rasoulian ◽  
...  
Keyword(s):  
In Silico ◽  
Anticonvulsant Agents

Design, synthesis, and biological evaluation studies of novel quinazolinone derivatives as anticonvulsant agents

2013 ◽  
Vol 22 (12) ◽  
pp. 5823-5831 ◽  
Author(s):  
Mohamed F. Zayed ◽  
Hany E. A. Ahmed ◽  
Abdel-Sattar M. Omar ◽  
Adel S. Abdelrahim ◽  
Khaled El-Adl
Keyword(s):  
Evaluation Studies ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Anticonvulsant Agents ◽  
Quinazolinone Derivatives ◽  
Synthesis And Biological Evaluation

ChemInform Abstract: Synthesis, Structural and Biological Characterization of 5-Phenylhydantoin Derivatives as Potential Anticonvulsant Agents.

ChemInform ◽  
2013 ◽  
Vol 44 (2) ◽  
pp. no-no
Author(s):  
Nemanja Trisovic ◽  
Tamara Timic ◽  
Jovana Divljakovic ◽  
Jelena Rogan ◽  
Dejan Poleti ◽  
...  
Keyword(s):  
Biological Characterization ◽  
Anticonvulsant Agents

SYNTHESIS OF NOVEL QUINAZOLIN-4(3H)-ONYL AZETIDINONES AS POTENTIAL ANTICONVULSANT AGENTS

INDIAN DRUGS ◽  
2017 ◽  
Vol 54 (11) ◽  
pp. 22-27
Author(s):  
A. Singh ◽  
Keyword(s):  
Magnetic Resonance ◽  
Acute Toxicity ◽  
Anticonvulsant Activity ◽  
Proton Magnetic Resonance ◽  
Acetyl Chloride ◽  
Mass Analysis ◽  
Substituted Anilines ◽  
Anticonvulsant Agents

A series of 4-(substituted aryl)- 1- [2’- methyl-6’- substituted anilino quinazolinon-4’-(3’H)-onyl ] -3- chloroazetidin- 2-ones 14-25 have been synthesized by addition of substituted anilines to 4-(substituted aryl)- 1- [2’- methyl-6’- bromoquinazolinon-4’-(3’H)-onyl ] -3- chloro- azetidin-2-ones 8-13 which in turn were prepared by the cycloaddition of triethylamine in dioxane to 3-(N-substituted benzylidene amino phenyl amido )-2-methyl-6-bromoquinazolin-4(3H)-ones 2-7 in presence of acetyl chloride. These compounds were screened for anticonvulsant activity and acute toxicity. Compound 4-(substituted aryl)- 1- [2’- methyl-6’- substituted anilino quinazolinon-4’-(3’H) – onyl ] -3- chloro-azetidinone showed most potent activity. The structure of all the synthesized compounds were delineated by elemental (C, H, N ) and spectra (IR, proton magnetic resonance and mass ) analysis.

scholarly journals Design, synthesis, pharmacological evaluation, and docking study of new acridone-based 1,2,4-oxadiazoles as potential anticonvulsant agents

2016 ◽  
Vol 112 ◽  
pp. 91-98 ◽  
Author(s):  
Maryam Mohammadi-Khanaposhtani ◽  
Mohammad Shabani ◽  
Mehrdad Faizi ◽  
Iraj Aghaei ◽  
Reza Jahani ◽  
...  
Keyword(s):  
Docking Study ◽  
Design Synthesis ◽  
Anticonvulsant Agents ◽  
Pharmacological Evaluation

3-Alkyl-4-aminobutyric acids: the first class of anticonvulsant agents that activates L-glutamic acid decarboxylase

1991 ◽  
Vol 34 (7) ◽  
pp. 2295-2298 ◽  
Author(s):  
Richard B. Silverman ◽  
Ryszard Andruszkiewicz ◽  
Shrenik M. Nanavati ◽  
Charles P. Taylor ◽  
Mark G. Vartanian
Keyword(s):  
Glutamic Acid ◽  
Glutamic Acid Decarboxylase ◽  
Acid Decarboxylase ◽  
Anticonvulsant Agents
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