Potential of a Standalone Computer-Aided Detection System for Breast Cancer Detection in Screening Mammography

Author(s):  
Jaime Melendez ◽  
Clara I. Sánchez ◽  
Rianne Hupse ◽  
Bram van Ginneken ◽  
Nico Karssemeijer
Radiology ◽  
2004 ◽  
Vol 231 (1) ◽  
pp. 208-214 ◽  
Author(s):  
Mark A. Helvie ◽  
Lubomir Hadjiiski ◽  
Erini Makariou ◽  
Heang-Ping Chan ◽  
Nicholas Petrick ◽  
...  

2021 ◽  
Vol 67 (6) ◽  
pp. 777-784
Author(s):  
Rustem Khasanov ◽  
Munir Tukhbatullin ◽  
Dmitrii Pasynkov

Purpose. To assess the influence of mammography mapping with the help of computer-aided detection system (CAD) MammCheck II of our own design on the relapse-free survival (RFS) in breast cancer (BC) patients detected during the combined (mammographic and ultrasound [US]) screening. Materials and methods. 10732 women aged 40-87 years old (mean age: 52.20±8.63) who performed mammography were randomized to the standard screening group (mammography → US of the dense breasts) or to the group of CAD-assisted screening (mammography → CAD → targeted US of suspicious CAD markings, as well as the standard US of the dense breasts; CAD group). The primary endpoint was the 3-years RFS. Results. Totally, in the standard screening group we identified 230 BCs (4.29%), in the CAD group — 248 BCs (4.62%; p>0.05), including 49 (21.20%) и 88 (35.48%) 0-I stage BCs, respectively (p<0.05). Median of the primary tumor size was significantly lower in the CAD group (18 mm) compared to the standard screening group (25 mm; р<0.05). 3-years RFS was significantly higher (87.90%) in the CAD group compared to the standard screening group (81.20%; р<0.05). Conclusion. Breast US after the previous mammography CAD mapping significantly increases the 3-years RFS of women with combined screening-detected BC.


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