Islet Cell Tumours

2010 ◽  
pp. 771-789 ◽  
Author(s):  
Sara Ekeblad
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumours

Localization of small islet-cell tumours

1984 ◽  
Vol 104 (4_Supplb) ◽  
pp. S22-S23
Author(s):  
R. GÜNTHER ◽  
K. J. KLOSE ◽  
K. RÜCKERT ◽  
F. P. KUHN ◽  
H. J. KLOTTER
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumours

Angiographic Appearances of Islet Cell Tumours of the Pancreas

1985 ◽  
Vol 29 (2) ◽  
pp. 142-146
Author(s):  
M. PUVANESWARY ◽  
MASOOD AFZAL
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumours

Imaging islet cell tumours

1994 ◽  
Vol 49 (5) ◽  
pp. 295-303 ◽  
Author(s):  
C.M.P. King ◽  
R.H. Reznek ◽  
J.E. Dacie ◽  
J.A.H. Wass
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumours

scholarly journals Expression of the C-terminal flanking peptide of human progastrin in human gastroduodenal mucosa, G-cell hyperplasia and islet cell tumours producing gastrin

1987 ◽  
Vol 1 (1) ◽  
pp. 95-108 ◽  
Author(s):  
M. Hara ◽  
I.M. Varndell ◽  
A.E. Bishop ◽  
M. Aitchison ◽  
J. Rode ◽  
...  
Keyword(s):  
Islet Cell ◽  
Cell Hyperplasia ◽  
G Cell ◽  
Gastroduodenal Mucosa ◽  
Islet Cell Tumours

Syndromes of Islet-cell Tumours of the Pancreas

BMJ ◽  
1959 ◽  
Vol 1 (5131) ◽  
pp. 1231-1232 ◽  
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumours

Canine pancreatic islet cell tumours secreting insulin-like growth factor type 2: a rare entity

2014 ◽  
Vol 14 (2) ◽  
pp. 170-180 ◽  
Author(s):  
R. Finotello ◽  
L. Ressel ◽  
M. Arvigo ◽  
G. Baroni ◽  
V. Marchetti ◽  
...  
Keyword(s):  
Growth Factor ◽  
Pancreatic Islet ◽  
Islet Cell ◽  
Insulin Like Growth Factor ◽  
Rare Entity ◽  
Pancreatic Islet Cell ◽  
Islet Cell Tumours ◽  
Factor Type

Spontaneous pancreatic islet cell tumours in guinea pigs

1979 ◽  
Vol 89 (4) ◽  
pp. 471-480 ◽  
Author(s):  
A. Yoshida ◽  
Z.M. Iqbal ◽  
S.S. Epstein
Keyword(s):  
Pancreatic Islet ◽  
Guinea Pigs ◽  
Islet Cell ◽  
Pancreatic Islet Cell ◽  
Islet Cell Tumours

Defective regulation of glucokinase in rat pancreatic islet cell tumours

1987 ◽  
Vol 115 (4) ◽  
pp. 514-520 ◽  
Author(s):  
Sigurd Lenzen ◽  
Markus Tiedge ◽  
Peter R. Flatt ◽  
Clifford J. Bailey ◽  
Uwe Panten
Keyword(s):  
B Cells ◽  
Pancreatic Islets ◽  
Islet Cell ◽  
Pancreatic Islet Cell ◽  
Hexokinase Activity ◽  
Radiation Induced ◽  
Glucose Phosphorylation ◽  
Islet Cell Tumours ◽  
Total Glucose ◽  
Rat Pancreatic Islet

Abstract. The role of glucokinase in the regulation of insulin secretion was examined in normal rat pancreatic islets and in chemically- and radiation-induced rat pancreatic B-cell tumours which show an impaired insulin secretory response to glucose. In normal rats glucokinase activity in cytoplasmic fractions of pancreatic islets was decreased with the duration of fasting and increased by refeeding or insulin administration. This observation is consistent with the induction of glucokinase by insulin. Hexokinase activity was only slightly reduced during fasting. Glucokinase activity decreased in cytoplasmic fractions of streptozotocin-nicotinamideinduced rat pancreatic islet cell tumours. Glucokinase activity contributed about 75% to the total glucose phosphorylation capacity in cytoplasmic fractions of normal pancreatic islets and of small (< 1 mg) streptozotocin-nicotinamide-tumours. This proportion decreased to about 20% in the large streptozotocin-nicotinamide tumours. Glucokinase activity in cytoplasmic fractions of transplantable radiation-induced NEDH (New England Deaconess Hospital) rat B-cell tumours was seven times lower than in normal pancreatic islets and contributed only 15% to the total glucose phosphorylation capacity. In contrast, hexokinase activity of the NEDH tumour B-cells was 2.5 times higher than normal. Decreased glucokinase activity in the chemically- and radiation-induced tumour B-cells appears to result from a loss of the ability of insulin to induce this enzyme and may explain the lack of insulin secretory responsiveness of these tumour B-cells.

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