Pharmacokinetics of recombinant human erythropoietin in children with renal failure

1992 ◽  
Vol 6 (3) ◽  
pp. 277-277
Author(s):  
J. H. C. Evans ◽  
J. T. Brocklebank ◽  
C. J. Bowmer ◽  
P. C. Ng
Keyword(s):  
Renal Failure ◽  
Recombinant Human Erythropoietin ◽  
Human Erythropoietin

▾ Epoetin – an important advance

1992 ◽  
Vol 30 (8) ◽  
pp. 29.2-32
Keyword(s):  
Renal Failure ◽  
Recombinant Human Erythropoietin ◽  
Antibody Formation ◽  
Blood Transfusions ◽  
Red Cell ◽  
Important Advance ◽  
Human Erythropoietin ◽  
Cell Antibody ◽  
Erythropoietin Deficiency ◽  
Made In

Erythropoietin is the endogenous hormone controlling red blood cell production. Most is made in the kidneys; if they fail, erythropoietin levels fall and anaemia develops. Treatment of erythropoietin deficiency anaemia in patients with renal failure has depended on repeated blood transfusions. Despite transfusions most patients remain anaemic and in addition are exposed to the risks of transfusion, such as viral infection, iron overload and problems associated with red cell antibody formation. The erythropoietin gene has been cloned and recombinant human erythropoietin (rHuEPO) is now marketed under the generic name epoetin. In this article we discuss the use of epoetin to treat anaemia in patients with renal failure and other potentially responsive conditions.

Treatment of the anemia of chronic renal failure with subcutaneous recombinant human erythropoietin

1990 ◽  
Vol 89 (4) ◽  
pp. 432-435 ◽  
Author(s):  
Alan J. Watson ◽  
Luis F. Gimenez ◽  
Sandra Cotton ◽  
Mackenzie Walser ◽  
Jerry L. Spivak
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Recombinant Human Erythropoietin ◽  
Human Erythropoietin

Effect of purified recombinant human erythropoietin on anemia in rats with experimental renal failure induced by five-sixth nephrectomy

Biotherapy ◽  
1990 ◽  
Vol 2 (1) ◽  
pp. 77-85 ◽  
Author(s):  
Akinori Kawamura ◽  
Masato Higuchi ◽  
Nobuo Imai ◽  
Tsutomu Kawaguchi ◽  
Yohsuke Ogura
Keyword(s):  
Renal Failure ◽  
Recombinant Human Erythropoietin ◽  
Human Erythropoietin ◽  
Experimental Renal Failure

scholarly journals Improvement of Anemia Associated with Chronic Renal Failure by Recombinant Human Erythropoietin Treatment in ICR-Derived Glomerulonephritis (ICGN) Mice

2004 ◽  
Vol 66 (7) ◽  
pp. 883-886 ◽  
Author(s):  
Misuzu YAMAGUCHI-YAMADA ◽  
Noboru MANABE ◽  
Yasufumi GOTO ◽  
Sayuri ANAN ◽  
Keiko MIYAMOTO ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Recombinant Human Erythropoietin ◽  
Human Erythropoietin ◽  
Erythropoietin Treatment

Recombinant human erythropoietin reduces rhabdomyolysis-induced acute renal failure in rats

Injury ◽  
2012 ◽  
Vol 43 (3) ◽  
pp. 367-373 ◽  
Author(s):  
Fwu-Lin Yang ◽  
Yi-Maun Subeq ◽  
Yi-Han Chiu ◽  
Ru-Ping Lee ◽  
Chung-Jen Lee ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Recombinant Human Erythropoietin ◽  
Human Erythropoietin
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