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Author(s):  
Sulagna Ghose

Abstract: Cookies are made in many wide ranges of processing and product characteristics. These cookies are made from Quinoa flour which are grounded into fine powder. Cookies had been made by different methods using different ingredients by different cultures. The main aim for this prepared cookie was to developed a cookie using Quinoa flour with Bean powder supplemented with Rolled Oatmeal. The Quinoa flour and the Bean powder are being treated at different levels. (T0) is made as normal cookie found in market with white wheat flour by using 65.2g of white wheat flour and other ingredients i.e., Extra virgin olive oil, Brown sugar and baking powder as (65.2:14:20:0.8) which is served as control, in (T1) with 35.2g of Quinoa flour and 15g of Bean powder i.e., (35.2:15), in (T2) with 30.2g of Quinoa flour and 20g of Bean powder i.e., (30.2:20), in (T3) with 25.5g Quinoa flour and 25g Bean powder i.e., (25.2:25). The study was conducted to developed cookies fortified with Quinoa flour, Bean powder and Rolled Oatmeal. Trials were conducted to adjust the most acceptable levels of Quinoa flour (35.2g, 30.2g and 25.2g) and Bean powder (15g, 20g and 25g) on the basis of physio-chemical analysis of the product. The Final optimized product contains 1 which was highly acceptable and can be used to develop a product without adversely affecting the sensory attributes. The cookies prepared without addition of Quinoa flour and Bean powder supplemented with Rolled Oatmeal was treated as Control. The optimized product contains 4.13% Vitamin C, 5.13% Antioxidant and 5.92% Dietary Fiber. The product possesses good level of Vitamin C, Dietary fiber and Antioxidant. Keywords: Quinoa flour, bean powder, Rolled oatmeal, Extra virgin olive oil, Baking powder, White wheat flour, Sugar, Cookies, Physico -chemical analysis, Vitamin C, Antioxidant, Dietary fiber.


Author(s):  
Dr. Smitha Sambrani ◽  

Massive open online courses (MOOCs) is created greater prominence as a modern learning system mainly due to the advanced progress made in the area of Learning and Teaching Technology and. Covid pandemic also had open opportunities for Online Learning Platforms. Present study has focused on learners’ experience with various MOOCs platforms through online reviews and ratings, which were collected from Google play store and appbot application. Seven MOOCs platforms namely Coursera, edX, Udemy, Swayam, LinkedIn , Khan Academy and Upgrad are reviewed in this paper. The main objective is to compare the select MOOCs platforms in the area of users’ experience. Total number of reviews and rating has been taken for the study is 63, 652. The time frame of sample data was taken for last one year that is from 5th April, 2020 to 5th April, 2021. Sentiment analysis and chi-square test is applied to analyze the difference among the different MOOCs platforms. The major outcomes were the reviews and ratings of different platform found with very good uses experience.


2022 ◽  
Vol 12 (4) ◽  
pp. 854-861
Author(s):  
Jing Li ◽  
Bo Xie ◽  
Hu Wang ◽  
Chengsong Chen ◽  
Chengwu Pan ◽  
...  

Certain progress has been made in the therapeutic method against gastric cancer such as surgical operation combined with chemotherapy and radiation therapy in recent years. But the therapeutic efficacy and prognosis on gastric cancer was still not satisfactory. The function of exosome of miR-328–3p secreted by bone marrow stromal cells (BMSCs) on restraining the gastric cancer was studied in the present study. The BMSCs with highly-expressed miR-328-3p was established. The exosome in cell supernatant was collected. The exosome of BMSCs and MSCs with highlyexpressed miR-328-3p was added into SGC-7901 cells followed by analysis of miR-328-3p level by Real-time PCR and TFF3 (Trefoil Factor 3) level in exosome by Western blot, cell proliferation, expression of E-cadherin, Vimentin and Caspase-3. miR-328-39 expression was reduced and TFF3 was elevated in gastric cancer tissue (P < 0.05). miR-328-3p was upregulated and TFF3 was downregulated after addition of BMSCs exosomes along with increased cell proliferation and reduced E-cadherin and Caspase3 expression (P < 0.05). In conclusion, exosome of BMSCs could be regulated by miR-328-3p and TFF3 expression is restrained so as to regulate the biological behaviors of gastric cancer cell.


2022 ◽  
pp. 074873042110694
Author(s):  
Miguel F. Perea ◽  
Daniel A. Perdomo ◽  
Zenaida A. Corredor ◽  
Mario González ◽  
Hugo Hernandez-Fonseca ◽  
...  

A robust body of evidence has demonstrated that the lunar cycle plays an important role in the reproduction of fish living in natural environments. However, little is known about the influence of the moon on tilapia reproductive activity in intensive fish farming systems. This study aims to evaluate the influence of the lunar cycle on the reproductive performance of tilapias in an intensive outdoor tropical production system in Latin America. Records of two tilapia strains (Nile tilapia [ Oreochromis niloticus; n = 75] and Red tilapia [ Oreochromis spp.; n = 1335]) reared in concrete tanks in a commercial fish farm were analyzed. Over a 3-year period, 60,136 captures were made in intervals of 12 to 14 days and 6,600 females were manually spawned. The number of females spawned and the volume of eggs collected from each tank ( n = 9) were recorded. Data was analyzed by the general linear model and means were compared by least squares means method. A very slight or no variation was observed when the lunar cycle was split into two halves (crescent and waning). The proportions of females spawned and the volume of eggs per spawned female and per female in the tank varied considerably across the eight periods of the lunar cycle, with greater values in the waning than in the crescent phase. A significantly greater proportion of tilapia spawned and yielded more eggs around the full moon than around the new moon and remaining days of the lunar cycle. The moon cycle affected the reproductive activity of tilapia, which were more reproductively active around the full moon and most of the waning phase.


Electrochem ◽  
2022 ◽  
Vol 3 (1) ◽  
pp. 58-69
Author(s):  
Valbonë Mehmeti ◽  
Fetah Podvorica

Alkylphosphonic acids are well known for their ability to form self-assembled monolayers on hydroxide surfaces. A crucial step to understanding fundamentally how these surfaces are created is the elucidation of the interaction process that leads to such interface creation. In this study, we employed electrochemical impedance spectroscopy (EIS), Monte Carlo and molecular dynamics to understand this process. The interaction with the Cu(111) surface of three different alkylphosphonic acids (hexyl-, octyl- and decylphosphonic acids) is evaluated in an aqueous acidic and in an ethanol solution by Monte Carlo and molecular dynamics simulations, while EIS measurements are used to put in evidence the impact of the layer made in ethanol on copper protection. Nyquist diagrams of copper samples modified with an alkylphosphonic monolayer showed a higher polarization resistance that mitigates the copper corrosion in an aqueous acid medium. The phase–frequency Bode plots had higher and broader phase maxima for a modified copper surface with phosphonic moieties, which confirmed the ability of this organic layer to prevent copper corrosion.


2022 ◽  
Vol 6 (POPL) ◽  
pp. 1-31
Author(s):  
Marco Campion ◽  
Mila Dalla Preda ◽  
Roberto Giacobazzi

Imprecision is inherent in any decidable (sound) approximation of undecidable program properties. In abstract interpretation this corresponds to the release of false alarms, e.g., when it is used for program analysis and program verification. As all alarming systems, a program analysis tool is credible when few false alarms are reported. As a consequence, we have to live together with false alarms, but also we need methods to control them. As for all approximation methods, also for abstract interpretation we need to estimate the accumulated imprecision during program analysis. In this paper we introduce a theory for estimating the error propagation in abstract interpretation, and hence in program analysis. We enrich abstract domains with a weakening of a metric distance. This enriched structure keeps coherence between the standard partial order relating approximated objects by their relative precision and the effective error made in this approximation. An abstract interpretation is precise when it is complete. We introduce the notion of partial completeness as a weakening of precision. In partial completeness the abstract interpreter may produce a bounded number of false alarms. We prove the key recursive properties of the class of programs for which an abstract interpreter is partially complete with a given bound of imprecision. Then, we introduce a proof system for estimating an upper bound of the error accumulated by the abstract interpreter during program analysis. Our framework is general enough to be instantiated to most known metrics for abstract domains.


2022 ◽  
Vol 7 (4) ◽  
pp. 723-727
Author(s):  
Varun Upadhyay ◽  
Sujata Lakhtakia ◽  
Baldev Sastya ◽  
Anamika Tiwari

To study the clinical profile of anterior uveitis in patients attending the Ophthalmology department of tertiary health centre of central India A cross-sectional, observational study was done in the department of Ophthalmology of tertiary health centre from January 2017 to July 2019. A total of 199 cases of anterior uveitis were studied to assess their clinical presentation and etiology. After thorough history taking, demographic data and clinical pattern were documented. Comprehensive ophthalmic evaluation, necessary laboratory investigations and radiological imaging were performed to establish the etiology. The maximum number (n=79; 39.7%) of patients were in the age group of 21-40 years and the mean age of the study subjects was 36.9+21.8 years. The male to female ratio was 1:1.42 (117 females, 82 males). Uniocular disease was found in 91.95% cases and majority (n=175; 87.93%) of the patients had acute presentation with 95.47% cases having non granulomatous uveitis. A specific diagnosis could not be made in 62.8% cases. Trauma (21.7%) was the most common cause in patients with a specific diagnosis. Persistent posterior synechiae was the most frequently seen complication (21.08%) although majority of the patients (66.8%) did not reveal any major complications.Patients with anterior uveitis most commonly had acute presentation. The disease was rarely bilateral and was mostly non-granulomatous in presentation. It was mostly idiopathic and among the known etiological factors, trauma was the most common cause.


Author(s):  
Saket Mehrotra

Squamous cell carcinoma is the most important and the most common malignant mucosal neoplasm of the head and neck accounting for over 90% of all malignancies. Conventional oral Squamous cell carcinoma is frequently present in general cancerous conditions. It is bundled up with six different variants. Histomorphologically every variant shows a unique appearance. This raises an opportunity for the different diagnostic consideration with the precise management decision.All cases of OSCC reported at our institution Dentopath Pathologies Amravati in past two months were scrutinized. Representative sections containing the full thickness of the tumor were used for histopathological grading. The structure and identification of carcinomas were done microscopically by two expert dentopathologist.In the present study, we screened 100 slides of a conventional epithelial cell carcinoma. Amonst which 30 Slides showed the verrucous carcinoma. On 5 slides adenoid squamous cell carcinoma were observed. Incidence of Papillary squamous cell carcinoma and basaloid squamous cell carcinoma was only 1 out of 100 slides each. Whereas, the spindle cell/sarcomatoid carcinoma was observed on 2 slides. Adenosquamous carcinoma is the rarest variant and hence no incidence of this carcinoma were observed in our study. The behavior of the OSCC varies amongst due to the presence of different morphological type of tumor. A few studies on OSCC malignancy grading with different clinical parameters were made. In the present study different types of variants are seen according to their histopathological appearances.Histopathological knowledge is very important for the precise diagnosis. Squamous cell carcinoma is the most common neoplasm of oral cavity. However, variants of the same show very less frequency. Hence, it became challenge for the appropriate diagnosis as many times a misdiagnosis affects the course of treatment of the patient


MEST Journal ◽  
2022 ◽  
Vol 10 (1) ◽  
pp. 60-65
Author(s):  
Ewa Salkiewicz-Munnerlyn

The present contribution deals with the issue of human rights in armed conflicts versus the concept of war. This distinction was made in Article 2, and the same in all four Geneva Convention of 1949. In this article, the distinction is made between the universal system of human rights and the International Humanitarian Law of Armed Conflicts (IHLAC). The difference of application between these two sets of law relies on the fact, that the universal agreements of human rights always apply, both in armed conflict and peace when the IHLAC applies only in times of armed conflicts. There is a difference between them in the regulation. Human rights regulate the relationship between the state and persons under its jurisdiction, regardless of their nationality and the IHLAC applies to states and individuals or armed groups distinguishing between a civilian or a veteran. About the compliance control, it is a different system too, for the IHLAC, it is the ICRC and criminal tribunals, and for human rights, there are different committees of tribunals like the International Court of Justice (ICJ). The exam of the jurisprudence of the ECtHR shows, that it does not make a distinction between a state of war and peace, which is called the humanization of the law of armed conflicts. Also, the very important question of the fragmentation of international law is examined, based on the jurisprudence of the ICJ.


2022 ◽  
Vol 2022 ◽  
pp. 1-9
Author(s):  
Zhifeng Liu ◽  
Yi Jiao ◽  
Tianyuan Yu ◽  
Hourong Wang ◽  
Yingqi Zhang ◽  
...  

Inflammatory bowel disease (IBD) is a chronic inflammatory disease with a high prevalence and canceration rate. The immune disorder is one of the recognized mechanisms. Acupuncture is widely used to treat patients with IBD. In recent years, an increasing number of studies have proven the effectiveness of acupuncture in the treatment of IBD, and some progress has been made in the mechanism. In this paper, we reviewed the studies related to acupuncture for IBD and focused on the immunomodulatory mechanism. We found that acupuncture could regulate the innate and adaptive immunity of IBD patients in many ways. Acupuncture exerts innate immunomodulatory effects by regulating intestinal epithelial barrier, toll-like receptors, NLRP3 inflammasomes, oxidative stress, and endoplasmic reticulum stress and exerts adaptive immunomodulation by regulating the balance of Th17/Treg and Th1/Th2 cells. In addition, acupuncture can also regulate intestinal flora.


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