Pituitary thyrotroph hyperplasia mimicking prolactin-secreting adenoma

1984 ◽  
Vol 7 (4) ◽  
pp. 399-404 ◽  
Author(s):  
A. Khalil ◽  
K. Kovacs ◽  
A. A. F. Sima ◽  
G. N. Burrow ◽  
E. Horvath
Keyword(s):  
Thyrotroph Hyperplasia

scholarly journals Reversible thyrotroph hyperplasia with hyperprolactinemia: A rare presenting manifestation of primary hypothyroidism

2012 ◽  
Vol 16 (6) ◽  
pp. 1037 ◽  
Author(s):  
Rajesh Rajput ◽  
Ashish Sehgal ◽  
Deepak Gahlan
Keyword(s):  
Primary Hypothyroidism ◽  
Thyrotroph Hyperplasia

scholarly journals Coexistence of Corticotroph Adenoma and Thyrotroph Hyperplasia in a Dog

2009 ◽  
Vol 71 (1) ◽  
pp. 93-98 ◽  
Author(s):  
Takahiro TESHIMA ◽  
Yasushi HARA ◽  
Kae SHIGIHARA ◽  
Susumu TAKEKOSHI ◽  
Yoshinori NEZU ◽  
...  
Keyword(s):  
Corticotroph Adenoma ◽  
Thyrotroph Hyperplasia

Thyrotroph hyperplasia

2013 ◽  
Vol 90 (1059) ◽  
pp. 56-57 ◽  
Author(s):  
Philip C Johnston ◽  
Peter K Ellis ◽  
Steven J Hunter
Keyword(s):  
Thyrotroph Hyperplasia

scholarly journals Dome-Shaped Pituitary Enlargement in Primary Hypothyroidism: Avoiding Neurosurgical Interventions

2020 ◽  
Vol 35 (2) ◽  
pp. 238-243
Author(s):  
Satyam Chakraborty ◽  
◽  
Mona Tiwari ◽  
Rajan Palui ◽  
Kajari Bhattacharya ◽  
...  
Keyword(s):  
Case Reports ◽  
Pituitary Surgery ◽  
Primary Hypothyroidism ◽  
Hormone Deficiency ◽  
Homogeneity Analysis ◽  
Imaging Characteristic ◽  
Pituitary Hyperplasia ◽  
Pituitary Enlargement ◽  
Levothyroxine Treatment ◽  
Thyrotroph Hyperplasia

We describe three cases of primary hypothyroidism which presented initially to neurosurgery department with pituitary hyperplasia. We have found a novel pattern of ‘dome shaped’ enlargement of pituitary in MRI of these patients. Out of these 3 patients, in two of them, the planned surgery was deferred when endocrinologists were consulted and the pituitary hyperplasia completely resolved with levothyroxine treatment. In the third case, pituitary surgery was already performed before endocrinology consultation and histopathology revealed thyrotroph hyperplasia. The hyperplastic lesions described typically have a homogenous symmetrical ‘dome’ shaped architecture unlike the non-functioning pituitary adenoma (NFPA), which usually might often be of varying shapes and homogeneity. Analysis of pituitary images from similar case reports published in literature, also showed this typical ‘dome’ shaped pituitary enlargement. This imaging characteristic can be a clue to look for underlying hormone deficiency, especially in primary hypothyroidism. Therefore, a thorough endocrine evaluation especially looking for primary hypothyroidism in such dome shaped pituitary lesions are mandatory to prevent unwarranted neuro-surgical intervention as treatment of primary hypothyroidism may result in resolution of the abnormal enlargement.

Abstract #806595: Primary Hypothyroidism and Thyrotroph Hyperplasia Progressing to Panhypopituitarism

2020 ◽  
Vol 26 ◽  
pp. 223-224
Author(s):  
Siddalingappa Chandraprabha
Keyword(s):  
Primary Hypothyroidism ◽  
Thyrotroph Hyperplasia

Abstract #511 Pituitary Macroadenoma Posted for Transphenoidal Surgery: Pituitary Thyrotroph Hyperplasia

2019 ◽  
Vol 25 ◽  
pp. 254-255
Author(s):  
Kavitha Muniraj ◽  
T Babitha ◽  
Vasanthi Nath ◽  
S Chandraprabha ◽  
Reshma Vijay ◽  
...  
Keyword(s):  
Pituitary Macroadenoma ◽  
Thyrotroph Hyperplasia

scholarly journals Primary Hypothyroidism Presenting as Growth Delay and Pituitary Enlargement

1988 ◽  
Vol 15 (1) ◽  
pp. 35-37 ◽  
Author(s):  
John D. Farley ◽  
Ellen L. Toth ◽  
Edmond A. Ryan
Keyword(s):  
Thyroid Disease ◽  
Visual Fields ◽  
Pituitary Surgery ◽  
Primary Hypothyroidism ◽  
Growth Delay ◽  
Pituitary Enlargement ◽  
Thyrotroph Hyperplasia

ABSTRACT:We report the case of a young boy being considered for pituitary surgery because of pituitary enlargement found during assessment of growth delay. There was no goitre but he was hypothyroid clinically and biochemically. The finding of an elevated TSH suggested primary thyroid disease with thyrotroph hyperplasia. Treatment with L-thyroxine resulted in prompt resolution of his pituitary enlargement and improvement in his visual fields.

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