scholarly journals Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3β,12β,25-triol derivatives as α-glucosidase and PTP1B inhibitors

2022 ◽  
Author(s):  
Xiao-Tong Yang ◽  
Tian-Ze Li ◽  
Chang-An Geng ◽  
Pei Liu ◽  
Ji-Jun Chen
Keyword(s):  
Biological Evaluation ◽  
Ptp1b Inhibitors ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of some N-(3-(1H-tetrazol-5-yl) phenyl)acetamide derivatives as novel non-carboxylic PTP1B inhibitors designed through bioisosteric modulation

2018 ◽  
Vol 80 ◽  
pp. 145-150 ◽  
Author(s):  
Neelesh Maheshwari ◽  
Chandrabose Karthikeyan ◽  
Shraddha V. Bhadada ◽  
Chandan Sahi ◽  
Amit K. Verma ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Ptp1b Inhibitors ◽  
Synthesis And Biological Evaluation

Design, synthesis and biological evaluation of some tetrazole acetamide derivatives as novel non-carboxylic PTP1B inhibitors

2019 ◽  
Vol 92 ◽  
pp. 103221 ◽  
Author(s):  
Neelesh Maheshwari ◽  
Chandrabose Karthikeyan ◽  
Shraddha V. Bhadada ◽  
Amit K. Verma ◽  
Chandan Sahi ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Ptp1b Inhibitors ◽  
Synthesis And Biological Evaluation

ChemInform Abstract: Synthesis and Biological Evaluation of Novel N-(Alkoxyphenyl)-aminocarbonylbenzoic Acid Derivatives as PTP1B Inhibitors.

ChemInform ◽  
2011 ◽  
Vol 42 (13) ◽  
pp. no-no
Author(s):  
Yuan Feng Tong ◽  
Pei Zhang ◽  
Feng Chen ◽  
Ling Hua Hao ◽  
Fei Ye ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Ptp1b Inhibitors ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of novel thiadiazole amides as potent Cdc25B and PTP1B inhibitors

2014 ◽  
Vol 24 (17) ◽  
pp. 4125-4128 ◽  
Author(s):  
Yingjun Li ◽  
Yang Yu ◽  
Kun Jin ◽  
Lixin Gao ◽  
Tongchuan Luo ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Ptp1b Inhibitors ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of novel bis-aromatic amides as novel PTP1B inhibitors

2014 ◽  
Vol 24 (8) ◽  
pp. 1889-1894 ◽  
Author(s):  
Wen-Long Wang ◽  
Chao Huang ◽  
Li-Xin Gao ◽  
Chun-Lan Tang ◽  
Jun-Qing Wang ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Ptp1b Inhibitors ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of novel N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives as PTP1B inhibitors

2010 ◽  
Vol 21 (12) ◽  
pp. 1415-1418 ◽  
Author(s):  
Yuan Feng Tong ◽  
Pei Zhang ◽  
Feng Chen ◽  
Ling Hua Hao ◽  
Fei Ye ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Ptp1b Inhibitors ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of novel 2,3-pyrazole ring-substituted-4,4-dimethyl lithocholic acid derivatives as selective protein tyrosine phosphatase 1B (PTP1B) inhibitors with cellular efficacy

RSC Advances ◽  
2015 ◽  
Vol 5 (129) ◽  
pp. 106551-106560 ◽  
Author(s):  
Shi-Wei Mao ◽  
Lin Shuai ◽  
Hai-Bing He ◽  
Na Pan ◽  
Li-Xin Gao ◽  
...  
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Lithocholic Acid ◽  
Tyrosine Phosphatase ◽  
Pyrazole Ring ◽  
Biological Evaluation ◽  
Cell Permeability ◽  
Protein Tyrosine Phosphatase 1B ◽  
Protein Tyrosine ◽  
Ptp1b Inhibitors ◽  
Synthesis And Biological Evaluation

Fourteen 2,3-pyrazole ring-substituted 4,4-dimethyl lithocholic acid derivatives were designed and synthesized as novel PTP1B inhibitors with good potency, selectivity as well as cell permeability.

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