A case of Salla disease with involvement of the cerebellar white matter

2003 ◽  
Vol 45 (2) ◽  
pp. 107-109 ◽  
Author(s):  
T. Linnankivi ◽  
T. Lönnqvist ◽  
T. Autti
Keyword(s):  
White Matter ◽  
Cerebellar White Matter ◽  
Salla Disease

Cerebellar white matter involvement in Salla disease

2004 ◽  
Vol 46 (7) ◽  
Author(s):  
Roberta Biancheri ◽  
A. Rossi ◽  
M.G. Mancini ◽  
C. Minetti
Keyword(s):  
White Matter ◽  
Cerebellar White Matter ◽  
Salla Disease

scholarly journals Mapping of long-term cognitive and motor deficits in pediatric cerebellar brain tumor survivors into a cerebellar white matter atlas

2021 ◽  
Author(s):  
Frederik Grosse ◽  
Stefan Mark Rueckriegel ◽  
Ulrich-Wilhelm Thomale ◽  
Pablo Hernáiz Driever
Keyword(s):  
Brain Tumor ◽  
Executive Function ◽  
Cognitive Function ◽  
White Matter ◽  
Cerebellar Nuclei ◽  
Motor Deficits ◽  
Deep Cerebellar Nuclei ◽  
Cerebellar White Matter ◽  
Lesion Symptom Mapping

Abstract Purpose Diaschisis of cerebrocerebellar loops contributes to cognitive and motor deficits in pediatric cerebellar brain tumor survivors. We used a cerebellar white matter atlas and hypothesized that lesion symptom mapping may reveal the critical lesions of cerebellar tracts. Methods We examined 31 long-term survivors of pediatric posterior fossa tumors (13 pilocytic astrocytoma, 18 medulloblastoma). Patients underwent neuronal imaging, examination for ataxia, fine motor and cognitive function, planning abilities, and executive function. Individual consolidated cerebellar lesions were drawn manually onto patients’ individual MRI and normalized into Montreal Neurologic Institute (MNI) space for further analysis with voxel-based lesion symptom mapping. Results Lesion symptom mapping linked deficits of motor function to the superior cerebellar peduncle (SCP), deep cerebellar nuclei (interposed nucleus (IN), fastigial nucleus (FN), ventromedial dentate nucleus (DN)), and inferior vermis (VIIIa, VIIIb, IX, X). Statistical maps of deficits of intelligence and executive function mapped with minor variations to the same cerebellar structures. Conclusion We identified lesions to the SCP next to deep cerebellar nuclei as critical for limiting both motor and cognitive function in pediatric cerebellar tumor survivors. Future strategies safeguarding motor and cognitive function will have to identify patients preoperatively at risk for damage to these critical structures and adapt multimodal therapeutic options accordingly.

scholarly journals P3-268: COGNITIVE CORRELATES OF CEREBELLAR WHITE MATTER TRACT DEGENERATION IN FRONTOTEMPORAL DEMENTIAS

2019 ◽  
Vol 15 ◽  
pp. P1039-P1040
Author(s):  
Yu Chen ◽  
Ramon Landin-Romero ◽  
Fiona Kumfor ◽  
Muireann Irish ◽  
John R. Hodges ◽  
...  
Keyword(s):  
White Matter ◽  
White Matter Tract ◽  
Cerebellar White Matter ◽  
Cognitive Correlates ◽  
Frontotemporal Dementias

An autopsied case of Sjögren's syndrome with massive necrotic and demyelinating lesions of the cerebellar white matter

2004 ◽  
Vol 225 (1-2) ◽  
pp. 143-148 ◽  
Author(s):  
Hiroo Ichikawa ◽  
Kenji Ishihara ◽  
Ryuhachiro Fujimoto ◽  
Takayuki Katoh ◽  
Masanobu Arai ◽  
...  
Keyword(s):  
White Matter ◽  
Sjögren’S Syndrome ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Cerebellar White Matter ◽  
Demyelinating Lesions ◽  
Sjögren‘S Syndrome

scholarly journals Multiple mechanisms underpin cerebral and cerebellar white matter deficits in Friedreich ataxia: The IMAGE‐FRDA study

2020 ◽  
Vol 41 (7) ◽  
pp. 1920-1933 ◽  
Author(s):  
Louisa P. Selvadurai ◽  
Louise A. Corben ◽  
Martin B. Delatycki ◽  
Elsdon Storey ◽  
Gary F. Egan ◽  
...  
Keyword(s):  
White Matter ◽  
Friedreich Ataxia ◽  
Cerebellar White Matter

scholarly journals Developmental Maturation of the Cerebellar White Matter—an Instructive Environment for Cerebellar Inhibitory Interneurons

2020 ◽  
Vol 19 (2) ◽  
pp. 286-308
Author(s):  
Anne Groteklaes ◽  
Carina Bönisch ◽  
Britta Eiberger ◽  
Andrea Christ ◽  
Karl Schilling
Keyword(s):  
White Matter ◽  
Inhibitory Interneurons ◽  
Cerebellar White Matter ◽  
Developmental Maturation
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