Sublingual versus vaginal misoprostol for cervical ripening before hysteroscopy: a randomized clinical trial

2012 ◽  
Vol 287 (5) ◽  
pp. 937-940 ◽  
Author(s):  
Fateme Davari Tanha ◽  
Shohreh Salimi ◽  
Mahsa Ghajarzadeh
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Cervical Ripening ◽  
Vaginal Misoprostol

scholarly journals Randomized clinical trial comparing the efficacy of vaginal misoprostol and Foley catheter for cervical ripening and induction of labour

2011 ◽  
Vol 9 (2) ◽  
pp. 88-90
Author(s):  
A Thakur ◽  
D Uprety ◽  
P Yadav ◽  
P Dahal ◽  
D Thaku
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Foley Catheter ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Vaginal Misoprostol

Keywords: Prostaglandin; Foley catheter; cervical ripening; induction of labourDOI: http://dx.doi.org/10.3126/hren.v9i2.4980Health Renaissance 2011: Vol.9 (No.2): 88-90

A Randomized Clinical Trial Comparing Vaginal Misoprostol versus Cervical Foley Plus Oral Misoprostol for Cervical Ripening and Labor Induction

2008 ◽  
Vol 26 (01) ◽  
pp. 033-038 ◽  
Author(s):  
James Hill ◽  
Brad Thigpen ◽  
James Bofill ◽  
Everett Magann ◽  
Lisa Moore ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Labor Induction ◽  
Cervical Ripening ◽  
Oral Misoprostol ◽  
Vaginal Misoprostol

scholarly journals Vaginal Misoprostol Versus Intracervical Foley Catheter for Cervical Ripening in Postdate Primigravid Women: a Randomized Clinical Trial

2021 ◽  
Author(s):  
Nazanin Abdi ◽  
Azin Alavi ◽  
Forough Pakbaz ◽  
Hossein Darabi
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Neonatal Intensive Care ◽  
Placental Abruption ◽  
Foley Catheter ◽  
Fetal Distress ◽  
Labor Induction ◽  
Cervical Ripening ◽  
Cervical Canal ◽  
Vaginal Misoprostol

Abstract Background: Being one of the most common indications of labor induction, postdate pregnancy can lead to serious maternal and fetal complications. In this study we aimed to compare vaginal misoprostol with intracervical Foley catheter (FC) for cervical ripening in postdate primigravid women. Methods: This randomized clinical trial included 120 primigravid women aged 18-35 years with singleton and postdate pregnancies and Bishop score ≤4. Participants were randomized into two equal groups. The first group received 25 µg vaginal misoprostol and the second group had an 18 Fr FC inserted into their cervical canal. Labor induction was performed using oxytocin in both groups if progression of labor or true contractions did not occur within 6 hours of the interventions. In case of nonreassuring fetal heart rate, fetal distress, placental abruption, or prolonged labor, C-section was performed. Results: The frequency of NVD, C-section, meconium-stained amniotic fluid, and neonatal intensive care unit admission did not differ significantly between groups. Placental abruption and uterine tachysystole occurred more frequently in the misoprostol group (15.0 vs. 1.7%, P=0.008 and 21.7 vs. 0.0%, P<0.001, respectively). A significantly higher number of women in the FC group required oxytocin (73.3 vs. 41.7%, P<0.001). Duration of labor was significantly higher in the FC group (P=0.001). Conclusions: Due to the lower rate of placental abruption and uterine tachysystole observed with FC, it appears to be superior to vaginal misoprostol for cervical ripening in postdate primigravid women; however, its longer labor duration and higher oxytocin requirement should be taken into consideration. Trial registration: Iranian Registry of Clinical Trials, IRCT20181218042033N4. Registered 19/04/2020. Retrospectively registered, https://www.irct.ir/trial/47037

scholarly journals Vaginal misoprostol versus intracervical Foley catheter for cervical ripening in postdate primigravid women: a randomized clinical trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nazanin Abdi ◽  
Azin Alavi ◽  
Forough Pakbaz ◽  
Hossein Darabi
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Placental Abruption ◽  
Foley Catheter ◽  
Labor Induction ◽  
Cervical Ripening ◽  
Normal Vaginal Delivery ◽  
Cervical Canal ◽  
Link Type ◽  
Vaginal Misoprostol

Abstract Background Being one of the most common indications of labor induction, postdate pregnancy can lead to serious maternal and fetal complications. In this study we aimed to compare vaginal misoprostol with intracervical Foley catheter (FC) for cervical ripening in postdate primigravid women. Methods This randomized clinical trial included 120 primigravid women aged 18–35 years with singleton,  postdate pregnancies, and Bishop score ≤ 4. Participants were randomized into two equal groups. The first group received 25 µg vaginal misoprostol and the second group had an 18 Fr FC inserted into their cervical canal. Labor induction was performed using oxytocin in both groups if progression of labor or true contractions did not occur within 6 h of the interventions. In case of nonreassuring fetal heart rate, fetal distress, placental abruption, or prolonged labor, C-section was performed. Results The frequency of normal vaginal delivery, Cesarean section, meconium-stained amniotic fluid, and neonatal intensive care unit admission did not differ significantly between groups. Placental abruption and uterine tachysystole occurred more frequently in the misoprostol group (15.0 vs. 1.7%, P = 0.008 and 21.7 vs. 0.0%, P < 0.001, respectively). A significantly higher number of women in the FC group required oxytocin (73.3 vs. 41.7%, P < 0.001). Duration of labor was significantly higher in the FC group (P = 0.001). Conclusions Due to the lower rate of placental abruption and uterine tachysystole observed with FC, it appears to be superior to vaginal misoprostol for cervical ripening in postdate primigravid women; however, its longer labor duration and higher oxytocin requirement should be taken into consideration. Trial registration Iranian Registry of Clinical Trials, IRCT20181218042033N4. Registered 19/04/2020. Retrospectively registered, https://www.irct.ir/trial/47037

scholarly journals The combination route versus sublingual and vaginal misoprostol for the termination of 13 to 24 week pregnancies: A randomized clinical trial

2015 ◽  
Vol 54 (6) ◽  
pp. 660-665 ◽  
Author(s):  
Fatemeh Rahimi-Sharbaf ◽  
Khadijeh Adabi ◽  
Mehrnaz Valadan ◽  
Mahboobeh Shirazi ◽  
Sepideh Nekuie ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Vaginal Misoprostol

Laminaria vs. vaginal misoprostol for cervical preparation before second-trimester surgical abortion: a randomized clinical trial

Contraception ◽  
2015 ◽  
Vol 91 (5) ◽  
pp. 406-411 ◽  
Author(s):  
Ron Sagiv ◽  
Yossi Mizrachi ◽  
Hagit Glickman ◽  
Ram Kerner ◽  
Ran Keidar ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Second Trimester ◽  
Cervical Preparation ◽  
Vaginal Misoprostol ◽  
Surgical Abortion
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