Linkage Study Revealed Complex Haplotypes in a Multifamily due to Different Mutations in CAPN3 Gene in an Iranian Ethnic Group

2016 ◽  
Vol 59 (3) ◽  
pp. 392-396 ◽  
Author(s):  
Marzieh Mojbafan ◽  
Seyed Hassan Tonekaboni ◽  
Maryam Abiri ◽  
Soudeh Kianfar ◽  
Ameneh Sarhadi ◽  
...  
2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
L Gruer ◽  
F Stanaway ◽  
R Bhopal

Abstract Background With growing numbers of migrants worldwide, accurate data are needed to assess the health of migrants and ethnic minorities, highlight inequalities and evaluate relevant policies and actions. To summarise and reveal the complexity of the findings, we developed data visualisation techniques based on epidemiological principles. Methods We used published results from the Scottish Health and Ethnicity Linkage Study (SHELS), a retrospective cohort of 4.62 million people linking census ethnicity data to health service and death records during 2001-2013. In tables mainly using rate ratios, we employed different colours to show health advantage, disadvantage or equivalence; different colour shades to represent degree of certainty, combining effect size and precision of estimate; and different font sizes for absolute rates, to highlight more common conditions. We ranked health conditions by age-adjusted rate within each ethnic group to show differences in burden of disease and disease priorities. Results Using 30 health outcomes for up to 11 ethnic groups, we show that ethnic differences vary greatly depending on outcome, sex and ethnic group. The patterns are complex with some ethnic groups showing strong advantages for some outcomes and strong disadvantages for others. Using absolute rates highlighted differences in common conditions such as myocardial infarction, COPD, and falls. Ranking conditions within ethnic groups showed that most ethnic groups have largely similar disease priorities. Conclusions Our approach helps reveal and interpret the complexity of ethnic health differences. Simplistic generalisations that the health of migrants or ethnic minorities is worse or better than majority populations are often misleading and best avoided. Using absolute rates and ranking conditions within ethnic groups are useful as large relative differences in disease rates between ethnic groups may not translate into different disease priorities. Key messages Statements that the health of migrants or ethnic minorities is worse or better than majority populations are often misleading and best avoided. Large relative differences in disease rates between ethnic groups may not translate into different disease priorities.


2006 ◽  
Vol 40 (9) ◽  
pp. 33
Author(s):  
MARY ANN MOON
Keyword(s):  

2008 ◽  
Author(s):  
Claire L. Sauvagnat ◽  
Jennifer M. Sanders ◽  
David V. Nelson ◽  
Stanley T. Kordinak ◽  
Marcus T. Boccaccini

2006 ◽  
Author(s):  
Juliette Schaafsma ◽  
Kipling Williams

2006 ◽  
Author(s):  
Wendy Soto ◽  
Dawn Fassih ◽  
Debby Martin ◽  
James Hsiao ◽  
Michele Wittig

2006 ◽  
Author(s):  
Sharon B. Hamill ◽  
Nancy Roherty ◽  
Kristi Dehnert ◽  
Julia Laplante ◽  
Stacey Race

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