Therapeutic Drug Monitoring Strategies for Envarsus in De Novo Kidney Transplant Patients Using Population Modelling and Simulations

2021 ◽  
Author(s):  
Emilie Henin ◽  
Mirco Govoni ◽  
Massimo Cella ◽  
Christian Laveille ◽  
Giovanni Piotti
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Kidney Transplant ◽  
Drug Monitoring ◽  
De Novo ◽  
Therapeutic Drug ◽  
Population Modelling ◽  
Transplant Patients ◽  
Monitoring Strategies ◽  
Kidney Transplant Patients ◽  
Modelling And Simulations

Specificity of Therapeutic Drug Monitoring of Tacrolimus in Kidney Transplant Patients

1998 ◽  
Vol 30 (4) ◽  
pp. 1274-1275 ◽  
Author(s):  
S. Sato ◽  
S. Fuchinoue ◽  
T. Tojimbara ◽  
S. Fujita ◽  
I. Nakajima ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Kidney Transplant ◽  
Drug Monitoring ◽  
Therapeutic Drug ◽  
Transplant Patients ◽  
Kidney Transplant Patients

Knowledge of immunosuppressive drugs used in kidney transplants

2012 ◽  
Vol 21 (13) ◽  
pp. 795-800
Author(s):  
Mas Linda Mohamad ◽  
Li Yang ◽  
Xu Jin ◽  
Priscilla Tan Lee Eng ◽  
Terence Kee Yi Shern
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Kidney Transplant ◽  
Drug Monitoring ◽  
Education Programme ◽  
Immunosuppressive Drugs ◽  
Therapeutic Drug ◽  
Kidney Transplant Recipients ◽  
Transplant Patients ◽  
High Dependency ◽  
Kidney Transplant Patients

Aim: A key role of renal nurses is the correct and safe administration of immunosuppressive drug therapy (ImmRx) to kidney transplant recipients. The authors sought to examine the knowledge and competency of ImmRx in kidney transplant patients and whether an annual kidney transplant nurse education programme had any beneficial effects. Methods: The study population was comprised of 63.2% (n=50/79) of all nurses from renal wards (ward A (n=17/35), ward B (n=21/32)) and 12 nurses from a high-dependency urology ward (ward C (n=12)). Kidney transplant patients usually receive inpatient care in wards A, B or C only as these wards specialise in urology and renal care. Each nurse completed a 35-question test that covered ImmRx in areas of indication, identification, interaction, pharmcokinetics/pharmacodynamics, therapeutic drug monitoring, administration and adverse effects. A minimum score of 70% was required to pass the test. Results: Only 46% of participants passed the test. The proportion of nurses who passed was not significantly different with respect to years of nursing experience, professional rank, postgraduate nursing qualifications or ward location. Unexpectedly, a greater proportion of nurses who did not attend the education programme passed the test (63.6%; n=14/22) than those who did attend it (32.1%; n=9/28]; p=0.03). Notably, 24% (n=12/50), 4% (n=2/50) and 4% (n=2/50) were unable to correctly answer any of the identification, interaction and therapeutic drug monitoring questions. Conclusion: These findings suggest that the nurses' understanding and knowledge of ImmRx is insufficient and they need to update their knowledge on ImmRx continually.

scholarly journals Therapeutic Drug Monitoring of Tacrolimus in Saudi Kidney Transplant Patients

2016 ◽  
Vol 06 (05) ◽  
Author(s):  
Marzog S Al Nasser ◽  
Ahmed S Ali ◽  
Mai A Abdul Sattar ◽  
Ezz H Abdulfattah ◽  
Lateef M Khan ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Kidney Transplant ◽  
Drug Monitoring ◽  
Therapeutic Drug ◽  
Transplant Patients ◽  
Kidney Transplant Patients

scholarly journals Pharmacokinetic considerations related to therapeutic drug monitoring of tacrolimus in kidney transplant patients

2017 ◽  
Vol 13 (12) ◽  
pp. 1225-1236 ◽  
Author(s):  
Louise M. Andrews ◽  
Yi Li ◽  
Brenda C. M. De Winter ◽  
Yun-Ying Shi ◽  
Carla C. Baan ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Kidney Transplant ◽  
Drug Monitoring ◽  
Therapeutic Drug ◽  
Transplant Patients ◽  
Kidney Transplant Patients
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