Fractional flow reserve for a mild stenosis on the donor artery to chronic total occlusion

2012 ◽  
Vol 28 (2) ◽  
pp. 193-196 ◽  
Author(s):  
Harue Sasai ◽  
Kenichi Sakakura ◽  
Koichi Yuri ◽  
Hiroshi Wada ◽  
Kenshiro Arao ◽  
...  
Author(s):  
Andrew Ladwiniec ◽  
Michael S. Cunnington ◽  
Jennifer Rossington ◽  
Adam N. Mather ◽  
Albert Alahmar ◽  
...  

2017 ◽  
Vol 70 (18) ◽  
pp. B105-B106
Author(s):  
Grigoris Karamasis ◽  
Shah Mohdnazri ◽  
Firas Al-Janabi ◽  
Andreas Kalogeropoulos ◽  
Rohan Jagathesan ◽  
...  

2020 ◽  
Vol 29 (1) ◽  
pp. 22-29 ◽  
Author(s):  
D. C. J. Keulards ◽  
P. J. Vlaar ◽  
I. Wijnbergen ◽  
N. H. J. Pijls ◽  
K. Teeuwen

AbstractStudies performed in the last two decades demonstrate that after successful percutaneous coronary intervention (PCI) of a chronically occluded coronary artery, the physiology of the chronic total occlusion (CTO) vessel and dependent microvasculature does not normalise immediately but improves significantly over time. Generally, there is an increase in fractional flow reserve (FFR) in the CTO artery, a decrease in collateral blood supply and an increase in FFR in the donor artery accompanied by an increase in blood flow and decrease in microvascular resistance in the myocardium supplied by the CTO vessel. Analogous to these physiological changes, positive remodelling of the distal CTO artery also occurs over time, and intravascular imaging can be helpful for analysing distal vessel parameters. Follow-up coronary angiography with physiological measurements after several weeks to months can be helpful and informative in a subset of patients in order to decide upon the necessity for treatment of residual coronary artery stenosis in the vessel distal to the CTO or in the contralateral donor artery, as well as in deciding whether stent optimisation is indicated. We suggest that such physiological guidance of CTO procedures avoids unnecessary overtreatment during the initial procedure, guides interventions at follow-up, and improves our understanding of what PCI in CTO means.


2018 ◽  
Vol 19 (6) ◽  
pp. 679-684
Author(s):  
Grigoris V. Karamasis ◽  
Andreas S. Kalogeropoulos ◽  
Shah H. Mohdnazri ◽  
Firas Al-Janabi ◽  
Rohan Jagathesan ◽  
...  

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