Growing Teratoma Syndrome Following Treatment for Immature Teratoma of Ovary-A Case Report and Review of Literature

ABSTRACT A total of 3 to 5% of all ovarian malignancies include malignant ovarian germ cell tumors (MOGCTs). They are subdivided into germinomatous and non-germinomatous tumors. Common types of non-germinomatous tumors include yolk sac and immature teratoma. Ovarian yolk sac tumors (YST) are the second most frequent histological subtype of MOGCTs, after ovarian dysgerminoma. They account for 20% of MOGCTs and are frequent especially in childhood and in early adulthood. We report the case of a yolk sac tumor of the ovary in a 13yrs years old female. How to cite this article Sreehari A, Rupakala BM, Sarojamma C. Ovarian Yolk Sac Tumor: A Case Report with Review of Literature. J Med Sci 2016;2(1):15-17.

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Immature teratoma at umbilicus region presenting as exomphalos: A case report with review of literature

Indian Journal of Medical and Paediatric Oncology ◽

10.4103/0971-5851.142042 ◽

2014 ◽

Vol 35 (3) ◽

pp. 231 ◽

Cited By ~ 6

Author(s):

LakshmiV Chavali ◽

RVijaya Bhaskar ◽

JBhaskar Reddy

Keyword(s):

Case Report ◽

Immature Teratoma ◽

Review Of Literature

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Growing teratoma syndrome and gliomatosis peritonei in 15-year-old female patient with immature ovarian teratoma – case report and review of literature

Journal of Pediatric and Adolescent Gynecology ◽

10.1016/j.jpag.2021.07.009 ◽

2021 ◽

Author(s):

Małgorzata Sawicka-Żukowsk ◽

Anna Krętowska-Grunwald ◽

Joanna Reszeć ◽

Maryna Krawczuk-Rybak

Keyword(s):

Case Report ◽

Female Patient ◽

Ovarian Teratoma ◽

Review Of Literature ◽

Growing Teratoma Syndrome ◽

Gliomatosis Peritonei

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Growing Teratoma Syndrome After Treatment of a Nonseminomatous Germ Cell Tumor: A Case Report and a Review of Literature

Urology Case Reports ◽

10.1016/j.eucr.2013.11.007 ◽

2014 ◽

Vol 2 (1) ◽

pp. 1-3 ◽

Cited By ~ 3

Author(s):

W. Boukettaya ◽

M. Hochlaf ◽

Z. Boudagga ◽

F. Ezzairi ◽

I. Chabchoub ◽

...

Keyword(s):

Case Report ◽

Germ Cell ◽

Germ Cell Tumor ◽

Cell Tumor ◽

Review Of Literature ◽

Growing Teratoma Syndrome ◽

Nonseminomatous Germ Cell Tumor

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Giant Congenital Intracranial Immature Teratoma: A Case Report and Review of Literature

Journal of Fetal Medicine ◽

10.1007/s40556-018-0173-3 ◽

2018 ◽

Vol 5 (3) ◽

pp. 193-195

Author(s):

Gazala Shahnaz ◽

Krishna Agarwal ◽

Ashish Jain ◽

Somolika Pal ◽

Gauri Gandhi

Keyword(s):

Case Report ◽

Immature Teratoma ◽

Review Of Literature

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Gliomatosis Peritonei Arising in Setting of Immature Teratoma of Ovary: A Case Report and Review of Literature

The Journal of Obstetrics and Gynecology of India ◽

10.1007/s13224-015-0708-7 ◽

2015 ◽

Vol 66 (3) ◽

pp. 192-195 ◽

Cited By ~ 2

Author(s):

Nisha Marwah ◽

Ashima Batra ◽

Sumiti Gupta ◽

Savita Rani Singhal ◽

Rajeev Sen

Keyword(s):

Case Report ◽

Immature Teratoma ◽

Review Of Literature ◽

Gliomatosis Peritonei

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Growing teratoma syndrome: A case report

10.1055/s-0039-1685323 ◽

2016 ◽

Author(s):

Swati Gupta ◽

Saritha Shamsunder ◽

Roli Purwar ◽

Vidya Jha ◽

A. K. Yadav ◽

...

Keyword(s):

Case Report ◽

Adnexal Mass ◽

Mature Teratoma ◽

Pelvic Mass ◽

Testicular Germ Cell Tumor ◽

Conservative Surgery ◽

Immature Teratoma ◽

Testicular Germ Cell ◽

Growing Teratoma Syndrome ◽

Sporadic Cases

Introduction: Growing teratoma syndrome (GTS) or chemotherapeutic retro conversion is an extremely rare phenomenon seen in about 1.9-7.6% of patients being treated for non-seminomatous testicular germ cell tumor. It is even more rarely reported in females with only sporadic cases reported so far. It was described by logothetis et al and is described as conversion of immature teratoma to mature one after chemotherapy and presents as growing and metastasizing mass. Case Report: We report a case of 10 year old girl who underwent conservative surgery for an adnexal mass reported as immature teratoma on histopathology. Following which she was given chemotherapy for rapidly developing ascites. After four cycles of chemotherapy, the pelvic mass increased in size with metastatic deposits around the liver. Re-laparotomy and removal of the ovarian mass and metastatic deposits was carried out in stages. The histopathology showed mature teratoma. Conclusion: GTS is an extremely rare occurrence and it is important for the clinicians to know it to avoid misdiagnosis. Moreover, being a chemo-resistant tumor, early diagnosis and surgery are curative.

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