Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

Teiichiro Koga; Yohko Shimada; Masao Kuroda; Yoshio Tsujita; Kazuo Hasegawa; Mitsuo Yamazaki

doi:10.1016/0005-2760(90)90139-o

Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism ◽

10.1016/0005-2760(90)90139-o ◽

1990 ◽

Vol 1045 (2) ◽

pp. 115-120 ◽

Cited By ~ 129

Author(s):

Teiichiro Koga ◽

Yohko Shimada ◽

Masao Kuroda ◽

Yoshio Tsujita ◽

Kazuo Hasegawa ◽

...

Keyword(s):

Reductase Inhibitor ◽

Cholesterol Synthesis ◽

Coenzyme A ◽

Selective Inhibition ◽

Pravastatin Sodium ◽

Coenzyme A Reductase

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Tissue-Selective Inhibition of Cholesterol Synthesis In Vitro and In Vivo by Pravastatin Sodium, a 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1990.tb42336.x ◽

1990 ◽

Vol 598 (1 Atheroscleros) ◽

pp. 532-534

Author(s):

TEIICHIRO KOGA ◽

YOHKO SHIMADA ◽

MASAO KURODA ◽

YOSHIO TSUJITA ◽

KAZUO HASEGAWA ◽

...

Keyword(s):

Reductase Inhibitor ◽

Cholesterol Synthesis ◽

Coenzyme A ◽

Selective Inhibition ◽

Pravastatin Sodium ◽

Coenzyme A Reductase

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The mechanism of lack of hypocholesterolemic effect of pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in rats

Atherosclerosis ◽

10.1016/0021-9150(94)93491-6 ◽

1994 ◽

Vol 109 (1-2) ◽

pp. 119-120

Author(s):

T. Fujioka ◽

F. Nara ◽

Y. Tsujita ◽

J. Fukushige ◽

M. Fukami ◽

...

Keyword(s):

Reductase Inhibitor ◽

Coenzyme A ◽

Hypocholesterolemic Effect ◽

Pravastatin Sodium ◽

Coenzyme A Reductase

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The mechanism of lack of hypocholesterolemic effects of pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in rats

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism ◽

10.1016/0005-2760(94)00154-q ◽

1995 ◽

Vol 1254 (1) ◽

pp. 7-12 ◽

Cited By ~ 62

Author(s):

Tomoyuki Fujioka ◽

Futoshi Nara ◽

Yoshio Tsujita ◽

Junichiro Fukushige ◽

Masaharu Fukami ◽

...

Keyword(s):

Reductase Inhibitor ◽

Coenzyme A ◽

Pravastatin Sodium ◽

Coenzyme A Reductase

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ChemInform Abstract: INFLUENCE OF INSULIN AND GLUCAGON ON THE CHOLESTEROL SYNTHESIS IN RAT LIVER IN VIVO. EVIDENCE AGAINST A RATE LIMITING FUNCTION OF THE HMG-COENZYME A REDUCTASE

Chemischer Informationsdienst ◽

10.1002/chin.197749361 ◽

1977 ◽

Vol 8 (49) ◽

Author(s):

O. WISS ◽

V. WISS

Keyword(s):

Rat Liver ◽

Cholesterol Synthesis ◽

Coenzyme A ◽

Rate Limiting ◽

Coenzyme A Reductase

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Inhibition of Cholesterol Synthesis in vitro and in vivo by ML-236A and ML-236B, Competitive Inhibitors of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1977.tb11637.x ◽

1977 ◽

Vol 77 (1) ◽

pp. 31-36 ◽

Cited By ~ 166

Author(s):

Akira ENDO ◽

Yoshio TSUJITA ◽

Masao KURODA ◽

Kazuhiko TANZAWA

Keyword(s):

Cholesterol Synthesis ◽

Coenzyme A ◽

Competitive Inhibitors ◽

Coenzyme A Reductase

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Inhibition of cholesterol synthesis ex vivo and in vivo by fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase

Cellular and Molecular Life Sciences ◽

10.1007/bf01931101 ◽

1995 ◽

Vol 51 (3) ◽

pp. 223-226 ◽

Cited By ~ 7

Author(s):

A. Yamamoto ◽

S. Itoh ◽

K. Hoshi ◽

K. Ichihara

Keyword(s):

Cholesterol Synthesis ◽

Coenzyme A ◽

Ex Vivo ◽

Coenzyme A Reductase

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Simvastatin, an HMG–Coenzyme A Reductase Inhibitor, Improves Endothelial Function Within 1 Month

Circulation ◽

10.1161/01.cir.95.5.1126 ◽

1997 ◽

Vol 95 (5) ◽

pp. 1126-1131 ◽

Cited By ~ 646

Author(s):

Gerard O'Driscoll ◽

Danny Green ◽

Roger R. Taylor

Keyword(s):

Endothelial Function ◽

Reductase Inhibitor ◽

Coenzyme A ◽

Coenzyme A Reductase

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Mevalonic acid-dependent degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo and in vitro.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)42396-9 ◽

1994 ◽

Vol 269 (1) ◽

pp. 633-638

Author(s):

C.C. Correll ◽

P.A. Edwards

Keyword(s):

Coenzyme A ◽

Mevalonic Acid ◽

Coenzyme A Reductase

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Regulation of Hepatic 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Synthesis

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)62216-1 ◽

1971 ◽

Vol 246 (10) ◽

pp. 3210-3216 ◽

Cited By ~ 27

Author(s):

David J. Shapiro ◽

Victor W. Rodwell

Keyword(s):

Cholesterol Synthesis ◽

Coenzyme A ◽

Coenzyme A Reductase

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A hydroxymethylglutaryl coenzyme a reductase inhibitor improves endothelial function within 7 days in patients with chronic hemodialysis

International Journal of Cardiology ◽

10.1016/j.ijcard.2009.05.023 ◽

2010 ◽

Vol 145 (1) ◽

pp. 21-26 ◽

Cited By ~ 10

Author(s):

Noriaki Kishimoto ◽

Toshio Hayashi ◽

Ichiro Sakuma ◽

Hatsuyo Kano-Hayashi ◽

Taku Tsunekawa ◽

...

Keyword(s):

Endothelial Function ◽

Reductase Inhibitor ◽

Coenzyme A ◽

Chronic Hemodialysis ◽

Hydroxymethylglutaryl Coenzyme A Reductase ◽

Coenzyme A Reductase

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