Phosphatidylcholine removal from brain lipid extracts expands lipid detection and enhances phosphoinositide quantification by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry

2007 ◽  
Vol 362 (2) ◽  
pp. 155-167 ◽  
Author(s):  
Roy A. Johanson ◽  
Roberto Buccafusca ◽  
Judy N. Quong ◽  
M. Alexander Shaw ◽  
Gerard T. Berry
2015 ◽  
Vol 54 (1) ◽  
pp. 5-6 ◽  
Author(s):  
Neil W. Anderson

An article in this issue of theJournal of Clinical Microbiology(J.-H. Youn, S. K. Drake, R. A. Weingarten, K. M. Frank, J. P. Dekker, and A. F. Lau, J Clin Microbiol 53:35–42, 2015,http://dx.doi.org/10.1128/JCM.01643-15) describes the use of matrix-assisted laser desorption ionization–time of flight (MALDI-TOF) mass spectrometry for the detection of organisms carrying ablaKPC-containing plasmid. This powerful and promising application highlights the challenges of using MALDI-TOF mass spectrometry for purposes other than organism identification.


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