Whole bowel irrigation in dapsone intoxication with persistent methemoglobinemia

2020 ◽  
Vol 38 (10) ◽  
pp. 2246.e1-2246.e2
Author(s):  
Indalecio Carboni Bisso ◽  
Nicolás Gemelli ◽  
Maria Paula Cordero ◽  
Cecilia Barrios ◽  
Daniel Pina
Keyword(s):  
Whole Bowel Irrigation

scholarly journals Lipid therapy for the treatment of a refractory amitriptyline overdose

CJEM ◽  
2012 ◽  
Vol 14 (03) ◽  
pp. 193-197 ◽  
Author(s):  
Mathew B. Kiberd ◽  
Samuel F. Minor
Keyword(s):  
Lipid Emulsion ◽  
Case Reports ◽  
Hemodynamic Instability ◽  
Tricyclic Antidepressant ◽  
Intentional Ingestion ◽  
Wide Complex Tachycardia ◽  
Whole Bowel Irrigation ◽  
Level Of Consciousness ◽  
Amitriptyline Overdose ◽  
Multiple Episodes

ABSTRACT Tricyclic antidepressant (TCA) overdose is a leading cause of death among intentional overdoses. Intravenous lipid emulsion therapy is an emerging antidote for local anesthetic toxicity, and there is animal evidence that lipid therapy may be efficacious in TCA overdose. Furthermore, case reports in humans have described the use of lipid therapy to reverse the toxicity of other lipophilic drugs. Here we report a 25-year-old female presenting with coma and hemodynamic instability following intentional ingestion of amitriptyline. She had multiple episodes of pulseless wide-complex tachycardia despite conventional treatment with chest compressions, cardioversion, lidocaine, epinephrine, norepinephrine, magnesium sulphate, sodium bicarbonate, activated charcoal, and whole bowel irrigation. Twenty percent lipid emulsion was administered intravenously (an initial 150 mL bolus, followed by an infusion at 16 mL/h and a second bolus of 40 mL) over 39 hours (total dose 814 mL) yet resulted in no dramatic changes in hemodynamics or level of consciousness. However, there was a decrease in the frequency of wide-complex tachycardia during the lipid emulsion infusion and a recurrence of wide-complex tachycardia shortly after the infusion was stopped. The patient was discharged from the intensive care unit 11 days later with no lasting physiologic sequelae.

Comparison of three methods of whole bowel irrigation

1980 ◽  
Vol 140 (3) ◽  
pp. 400-402 ◽  
Author(s):  
Stefano Minervini ◽  
John Alexander-Williams ◽  
Ian A. Donovan ◽  
Sandra Bentley ◽  
Michael R.B. Keighley
Keyword(s):  
Whole Bowel Irrigation

Comparison of Fluid Volumes with Whole Bowel Irrigation in a Simulated Overdose of Ibuprofen

1995 ◽  
Vol 29 (3) ◽  
pp. 246-250 ◽  
Author(s):  
Keith M. Olsen ◽  
Bill J. Gurley ◽  
George A. Davis ◽  
Scott R. Archer ◽  
Frank H. Ma ◽  
...  
Keyword(s):  
Whole Bowel Irrigation

Whole bowel irrigation during pregnancy

1989 ◽  
Vol 160 (3) ◽  
pp. 646-647 ◽  
Author(s):  
Kenneth J. Van Ameyde ◽  
Milton Tenenbein
Keyword(s):  
Whole Bowel Irrigation

Successful whole bowel irrigation in self-poisoning with potassium capsules

2008 ◽  
Vol 46 (10) ◽  
pp. 1102-1103 ◽  
Author(s):  
Jonas Höjer ◽  
Sune Forsberg
Keyword(s):  
Whole Bowel Irrigation

Five Days of Whole-Bowel Irrigation in a Case of Pediatric Iron Ingestion

1996 ◽  
Vol 27 (2) ◽  
pp. 258-263 ◽  
Author(s):  
Jeffrey M Kaczorowski ◽  
Paul M Wax
Keyword(s):  
Whole Bowel Irrigation

Whole Bowel Irrigation After Delayed Release Fenfluramine Overdose

1995 ◽  
Vol 33 (2) ◽  
pp. 161-163 ◽  
Author(s):  
Roberto Melandri ◽  
Giuseppe Re ◽  
Aristide Morigi ◽  
Chiara Lanzarini ◽  
Isabella Vaona ◽  
...  
Keyword(s):  
Delayed Release ◽  
Whole Bowel Irrigation
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