501: Prediction of spontaneous preterm delivery based on sonographic cervical length and gestational age at cervical length measurement in asymptomatic women with twin pregnancies

AbstractThe objective of our study was to evaluate the correlation of the cervical length at 20–25 weeks of gestation with the incidence of spontaneous preterm delivery in twins in a country with a high incidence of preterm delivery compared to other European countries. Cervical length was measured in 262 consecutive patients. Previous preterm delivery before 34 weeks of gestation, chorionicity, maternal age, body-mass-index, smoking habit and parity were recorded as risk factors for preterm delivery. Women who were symptomatic at 20–25 weeks and who delivered because of other reasons than spontaneous labour and preterm rupture of membranes or at term were excluded. The primary outcome was incidence of preterm birth before 34 weeks. Two hundred and twenty-three patients were analyzed. Thirty-two (14%) delivered before 34 weeks. There was a significant correlation between cervical length of less than 25 mm and spontaneous delivery before 34 weeks (50% vs. 13%,p= .007). In addition, logistic regression analysis found cervical length to be the only significant predictor of spontaneous delivery before 34 weeks (OR 1.084; 95% CI 1.015; 1.159;p= .017). We conclude that the risk of severe preterm delivery in twins is high. Cervical length at mid-gestation was the only predictor of delivery before 34 weeks.

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OC101: Transvaginal cervical length measurement as a predictor of preterm delivery in IVF patients

Ultrasound in Obstetrics and Gynecology ◽

10.1002/uog.5509 ◽

2008 ◽

Vol 32 (3) ◽

pp. 275-276

Author(s):

M. Wielgos ◽

I. Szymusik ◽

K. Kosinska-Kaczynska ◽

P. Marianowski ◽

W. Dziadecki ◽

...

Keyword(s):

Preterm Delivery ◽

Cervical Length ◽

Length Measurement ◽

Cervical Length Measurement

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Cervical Length Measurement for Prediction of Preterm Delivery

Donald School Textbook of PowerPoint Presentation on Advanced Ultrasound in Obstetrics and Gynecology ◽

10.5005/jp/books/12692_17 ◽

2015 ◽

pp. 157-157

Author(s):

Asim Kurjak ◽

Panos Antsaklis

Keyword(s):

Preterm Delivery ◽

Cervical Length ◽

Length Measurement ◽

Cervical Length Measurement

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Cervical Length as a Predictor of Preterm Delivery in an Unselected Cohort of Women with Twin Pregnancies

American Journal of Perinatology ◽

10.1055/s-0038-1676484 ◽

2018 ◽

Vol 36 (12) ◽

pp. 1288-1294 ◽

Cited By ~ 1

Author(s):

Clifton O. Brock ◽

Leslie A. Moroz ◽

Cynthia Gyamfi-Bannerman

Keyword(s):

Preterm Delivery ◽

Meta Analysis ◽

Area Under The Curve ◽

Positive Likelihood Ratio ◽

Cervical Length ◽

Prospective Data ◽

Spontaneous Preterm Delivery ◽

False Discovery ◽

Twin Pregnancies ◽

Unselected Cohort

Objective To determine the risk of spontaneous preterm delivery (SPTD) associated with transvaginal cervical length (TVCL) in an unselected cohort. Study Design This is a retrospective study of serial TVCLs in unselected twin gestations. Receiver operator curves for SPTD were constructed from TVCLs at 18, 20, 22, and 24 weeks. Prediction thresholds were determined using a false discovery rate of 10%. The risk of SPTD was compared with previously published, prospective data from a meta-analysis. Results A total of 1,228 women were included. SPTD occurred prior to 35 weeks in 232 (18.9%), 126 (10.3%), and 24 (2.0%) women prior to 35, 32, and 28 weeks. TVCL was most predictive at 22 weeks (area under the curve = 0.67). TVCL thresholds for predicting SPTD prior to 35, 32, and 28 weeks were 3.1, 3.0, and 2.9 cm. Compared with a previous meta-analysis, the risk of SPTD < 34, 32, and 28 weeks was lower (positive likelihood ratio 9.0 vs. 5.4, 10.1 vs. 5.9, and 9.6 vs. 4.3). Conclusion TVCL is modestly predictive of SPTD in twin gestations. Compared with previous prospective studies, this cohort has lower risk of SPTD at similar TVCLs.

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